A 型肉毒毒素对咀嚼肌的组织学和功能影响的系统回顾:牙颌面矫形和正颌外科手术中的考虑因素。

IF 2 3区 医学 Q2 ANATOMY & MORPHOLOGY Annals of Anatomy-Anatomischer Anzeiger Pub Date : 2024-07-20 DOI:10.1016/j.aanat.2024.152302
Jean-François Guignardat , Gwénaël Raoul , Joël Ferri , James J. Sciote , Romain Nicot
{"title":"A 型肉毒毒素对咀嚼肌的组织学和功能影响的系统回顾:牙颌面矫形和正颌外科手术中的考虑因素。","authors":"Jean-François Guignardat ,&nbsp;Gwénaël Raoul ,&nbsp;Joël Ferri ,&nbsp;James J. Sciote ,&nbsp;Romain Nicot","doi":"10.1016/j.aanat.2024.152302","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Botulinum toxin type A causes muscle paralysis and is widely used in the masticatory muscle for stomatognathic diseases, such as temporomandibular disorder, bruxism, or masseteric hypertrophy. Nonetheless, its muscular effect remains unclear. Better understanding could aid improved use and perhaps new indications, particularly in dentofacial orthopaedics and orthognathic surgery.</p></div><div><h3>Methods</h3><p>This systematic review explored the histologic and functional effects of botulinum toxin in animal and human masticatory muscles and was conducted in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The MEDLINE, Web of Science, and Cochrane Library electronic databases were searched for relevant articles. The inclusion criteria were human or animal masticatory muscle analysis after botulinum toxin injection(s) AND histological structural/ultrastructural analysis by optical or electronic microscopy OR functional effect analysis by bite force evaluation (occlusal force analyzer) and muscle activity (electromyography).</p></div><div><h3>Results</h3><p>Of an initial 1578 articles, 44 studies were eventually included. Botulinum toxin injection in the masticatory muscle altered its histological structure and functional properties. The human and animal studies revealed ultrastructural change, atrophy, and fiber type modifications of the masticatory muscles after one injection. Botulinum toxin decreased bite force and muscle activity, but recovery was uncertain.</p></div><div><h3>Conclusions</h3><p>Muscle forces applied on the skeleton is a key feature of facial growth. Masticatory muscle paralysis changes mechanical stress on bones, which rebalances the force applied on facial bones. This new balance could benefit dental deformity or surgical relapse. Therefore, botulinum toxin could limit the orthognathic effect of the masticatory muscles in such patients. Given the uncertain recovery, multiple injections should be avoided, and usage should not deviate from established consensus.</p></div>","PeriodicalId":50974,"journal":{"name":"Annals of Anatomy-Anatomischer Anzeiger","volume":"256 ","pages":"Article 152302"},"PeriodicalIF":2.0000,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Systematic review of the histological and functional effects of botulinum toxin A on masticatory muscles: Consideration in dentofacial orthopedics and orthognathic surgery\",\"authors\":\"Jean-François Guignardat ,&nbsp;Gwénaël Raoul ,&nbsp;Joël Ferri ,&nbsp;James J. Sciote ,&nbsp;Romain Nicot\",\"doi\":\"10.1016/j.aanat.2024.152302\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Botulinum toxin type A causes muscle paralysis and is widely used in the masticatory muscle for stomatognathic diseases, such as temporomandibular disorder, bruxism, or masseteric hypertrophy. Nonetheless, its muscular effect remains unclear. Better understanding could aid improved use and perhaps new indications, particularly in dentofacial orthopaedics and orthognathic surgery.</p></div><div><h3>Methods</h3><p>This systematic review explored the histologic and functional effects of botulinum toxin in animal and human masticatory muscles and was conducted in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The MEDLINE, Web of Science, and Cochrane Library electronic databases were searched for relevant articles. The inclusion criteria were human or animal masticatory muscle analysis after botulinum toxin injection(s) AND histological structural/ultrastructural analysis by optical or electronic microscopy OR functional effect analysis by bite force evaluation (occlusal force analyzer) and muscle activity (electromyography).</p></div><div><h3>Results</h3><p>Of an initial 1578 articles, 44 studies were eventually included. Botulinum toxin injection in the masticatory muscle altered its histological structure and functional properties. The human and animal studies revealed ultrastructural change, atrophy, and fiber type modifications of the masticatory muscles after one injection. Botulinum toxin decreased bite force and muscle activity, but recovery was uncertain.</p></div><div><h3>Conclusions</h3><p>Muscle forces applied on the skeleton is a key feature of facial growth. Masticatory muscle paralysis changes mechanical stress on bones, which rebalances the force applied on facial bones. This new balance could benefit dental deformity or surgical relapse. Therefore, botulinum toxin could limit the orthognathic effect of the masticatory muscles in such patients. Given the uncertain recovery, multiple injections should be avoided, and usage should not deviate from established consensus.</p></div>\",\"PeriodicalId\":50974,\"journal\":{\"name\":\"Annals of Anatomy-Anatomischer Anzeiger\",\"volume\":\"256 \",\"pages\":\"Article 152302\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Anatomy-Anatomischer Anzeiger\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0940960224000943\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ANATOMY & MORPHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Anatomy-Anatomischer Anzeiger","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0940960224000943","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ANATOMY & MORPHOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

简介A 型肉毒杆菌毒素可导致肌肉麻痹,被广泛用于咀嚼肌治疗颞下颌关节紊乱、磨牙症或咀嚼肌肥大等口腔疾病。然而,它对肌肉的作用仍不明确。更好地了解这种药物有助于改进其使用,或许还能增加新的适应症,尤其是在牙颌面矫形和正颌外科方面:本系统综述探讨了肉毒毒素对动物和人类咀嚼肌的组织学和功能影响,并根据《系统综述和荟萃分析首选报告项目》声明的建议进行。研究人员在 MEDLINE、Web of Science 和 Cochrane Library 电子数据库中检索了相关文章。纳入标准为肉毒毒素注射后的人类或动物咀嚼肌分析,以及通过光学或电子显微镜进行的组织结构/超微结构分析,或通过咬合力评估(咬合力分析仪)和肌肉活动(肌电图)进行的功能效果分析:在最初的 1578 篇文章中,最终纳入了 44 项研究。在咀嚼肌注射肉毒杆菌会改变其组织学结构和功能特性。人类和动物研究显示,注射一次肉毒杆菌毒素后,咀嚼肌的超微结构会发生变化、萎缩和纤维类型改变。肉毒杆菌毒素降低了咬合力和肌肉活动,但恢复情况并不确定:结论:施加在骨骼上的肌肉力量是面部生长的一个关键特征。咀嚼肌麻痹会改变骨骼上的机械应力,从而重新平衡施加在面部骨骼上的力量。这种新的平衡可能有利于牙齿畸形或手术复发。因此,肉毒杆菌毒素可限制此类患者咀嚼肌的正颌效应。鉴于恢复的不确定性,应避免多次注射,使用方法也不应偏离既定的共识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Systematic review of the histological and functional effects of botulinum toxin A on masticatory muscles: Consideration in dentofacial orthopedics and orthognathic surgery

Introduction

Botulinum toxin type A causes muscle paralysis and is widely used in the masticatory muscle for stomatognathic diseases, such as temporomandibular disorder, bruxism, or masseteric hypertrophy. Nonetheless, its muscular effect remains unclear. Better understanding could aid improved use and perhaps new indications, particularly in dentofacial orthopaedics and orthognathic surgery.

Methods

This systematic review explored the histologic and functional effects of botulinum toxin in animal and human masticatory muscles and was conducted in accordance with the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The MEDLINE, Web of Science, and Cochrane Library electronic databases were searched for relevant articles. The inclusion criteria were human or animal masticatory muscle analysis after botulinum toxin injection(s) AND histological structural/ultrastructural analysis by optical or electronic microscopy OR functional effect analysis by bite force evaluation (occlusal force analyzer) and muscle activity (electromyography).

Results

Of an initial 1578 articles, 44 studies were eventually included. Botulinum toxin injection in the masticatory muscle altered its histological structure and functional properties. The human and animal studies revealed ultrastructural change, atrophy, and fiber type modifications of the masticatory muscles after one injection. Botulinum toxin decreased bite force and muscle activity, but recovery was uncertain.

Conclusions

Muscle forces applied on the skeleton is a key feature of facial growth. Masticatory muscle paralysis changes mechanical stress on bones, which rebalances the force applied on facial bones. This new balance could benefit dental deformity or surgical relapse. Therefore, botulinum toxin could limit the orthognathic effect of the masticatory muscles in such patients. Given the uncertain recovery, multiple injections should be avoided, and usage should not deviate from established consensus.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annals of Anatomy-Anatomischer Anzeiger
Annals of Anatomy-Anatomischer Anzeiger 医学-解剖学与形态学
CiteScore
4.40
自引率
22.70%
发文量
137
审稿时长
33 days
期刊介绍: Annals of Anatomy publish peer reviewed original articles as well as brief review articles. The journal is open to original papers covering a link between anatomy and areas such as •molecular biology, •cell biology •reproductive biology •immunobiology •developmental biology, neurobiology •embryology as well as •neuroanatomy •neuroimmunology •clinical anatomy •comparative anatomy •modern imaging techniques •evolution, and especially also •aging
期刊最新文献
Advances in upper urinary tract anatomy through imaging techniques How to deal with the variability of peripheral nerve lesion patterns after inguinal herniotomy? A descriptive approach for a new terminology in clinical practice CT imaging analysis of the C7 pedicle and lateral mass in children aged 0–14 years The effect of Scheuermann's kyphosis on rib cage morphology: A skeletal study Caspase-12 affects chondrogenesis in mice
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1