骨盆圆周加压装置治疗下半身创伤的效果:日本创伤数据库回顾性研究的启示。

IF 1.5 Q2 MEDICINE, GENERAL & INTERNAL Acute Medicine & Surgery Pub Date : 2024-07-23 DOI:10.1002/ams2.983
Shohei Ono, Satoshi Miyata, Hiroaki Suzuki, Keiki Shimizu
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引用次数: 0

摘要

目的:高能量创伤导致的骨盆环形骨折(PRF)通常会导致严重出血和高死亡率。骨盆环形加压装置(PCCD)被广泛用于稳定骨盆环骨折并减少出血。然而,支持其有效性的证据仍无定论:我们利用日本创伤数据库(JTDB)在 2019 年至 2021 年期间开展了一项观察性研究。研究纳入了 15 岁或以上的下半身钝性创伤患者。我们使用倾向得分匹配(PSM)和逆概率治疗加权(IPTW)来评估 PCCD 与死亡率的关系:在数据库中的 74,393 名患者中,分析了 235 名 PCCD 组患者和 23,429 名对照组患者。在 PSM 之后,两组中均有 231 名患者入选。粗略分析显示,PCCD 组的院内死亡率明显更高(几率比 (OR) = 3.8 [95% CI = 2.51-5.75])。然而,PSM 和 IPTW 分析表明,PCCD 与院内死亡率下降相关(PSM:OR = 0.79 [0.43-1.42];IPTW:OR = 0.73 [0.62-0.86])。在 IPTW 分析的亚组分析中,PCCD 装配导致无 PRF 组的院内死亡率增加(OR = 2.08 [1.91-2.27]),稳定 PRF 下降(OR = 0.74 [0.6-0.91]),不稳定 PRF 进一步下降(OR = 0.18 [0.12-0.27])。其他因素,如从高处摔下、从楼下摔下、院前放置PCCD等,也会影响治疗效果:本项大型登记研究发现,PCCD 可降低下半身受伤患者的死亡率,尤其是 PRF 不稳定的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Effectiveness of pelvic circumferential compression device for lower body trauma: Insights from a Japan Trauma Data Bank retrospective study

Aim

Pelvic ring fractures (PRFs) due to high-energy trauma often result in severe bleeding and high mortality. Pelvic circumferential compression devices (PCCD) are widely used to stabilize PRF and decrease bleeding. However, evidence supporting their effectiveness is still inconclusive.

Methods

We conducted an observational study using the Japan Trauma Data Bank (JTDB) from 2019 to 2021. Patients with blunt lower body trauma aged 15 years or older were included. We used propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) to evaluate the association of PCCD and mortality.

Results

Of the 74,393 patients in the database, 235 PCCD group and 23,429 control group were analyzed. After PSM, 231 patients in both groups were enrolled. Crude analysis indicated significantly higher in-hospital mortality in the PCCD group (odds ratio (OR) = 3.8 [95% CI = 2.51–5.75]). However, PSM and IPTW analysis indicated that PCCD was associated with decreased in-hospital mortality (PSM: OR = 0.79 [0.43–1.42]; IPTW: OR = 0.73 [0.62–0.86]). In a subgroup analysis of the IPTW analysis, PCCD fitting resulted in increased in-hospital mortality in the group without PRF (OR = 2.08 [1.91–2.27]), a decrease in stable PRF (OR = 0.74 [0.6–0.91]), and a further decrease in unstable PRF (OR = 0.18 [0.12–0.27]). Additional factors, such as a fall from a height, a fall downstairs, and pre-hospital PCCD placement also influenced the treatment effect.

Conclusion

The present, large, registry-based study found that PCCD reduced mortality in patients with a lower body injury, especially those with an unstable PRF.

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来源期刊
Acute Medicine & Surgery
Acute Medicine & Surgery MEDICINE, GENERAL & INTERNAL-
自引率
12.50%
发文量
87
审稿时长
53 weeks
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