原发性高血压的首选利尿疗法：氯塞酮还是氢氯噻嗪？

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL Jaapa-Journal of the American Academy of Physician Assistants Pub Date : 2024-08-01 Epub Date: 2024-07-25 DOI:10.1097/01.JAA.0000000000000057

Trevor D Young

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引用次数: 0

摘要

摘要：由于氯塞酮能更有效地减少主要不良心血管事件（MACE），因此建议将其作为原发性高血压患者的首选利尿剂，而不是氢氯噻嗪。然而，与氯塞酮相比，氢氯噻嗪更常用于治疗原发性高血压。本文回顾了近期有关氯塞酮和氢氯噻嗪在降低MACE方面有效性的研究，以帮助临床医生在循证的基础上做出明智的决定，确定应处方哪种利尿剂。

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Preferred diuretic therapy for primary hypertension: Chlorthalidone or hydrochlorothiazide?

Abstract: Because of its greater reduction of major adverse cardiovascular events (MACE), chlorthalidone is recommended over hydrochlorothiazide as the preferred diuretic for patients with primary hypertension. However, hydrochlorothiazide is more commonly prescribed than chlorthalidone for this condition. This article reviews recent studies investigating the effectiveness of chlorthalidone and hydrochlorothiazide in reducing MACE, to help clinicians make an evidence-based informed decision on which diuretic to prescribe.

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来源期刊

Jaapa-Journal of the American Academy of Physician Assistants MEDICINE, GENERAL & INTERNAL-

CiteScore

1.20

自引率

9.10%

发文量

310

期刊介绍： JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues. Published monthly, JAAPA''s award-winning editorial includes: -Clinical review articles (with AAPA-approved Category I CME in each issue)- Case reports- Clinical departments- Original health services research- Articles on issues of professional interest to PAs

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