根据使用伽玛刀@ Perfexion™设备治疗强迫症计划中使用的参数,通过TL剂量测定进行剂量评估

IF 1.6 3区 物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Radiation Measurements Pub Date : 2024-07-18 DOI:10.1016/j.radmeas.2024.107251
Juan Valani Marques de Sousa , Crystian Wilian Chagas Saraiva , Odair Dias Gonçalves , Dirceu Dias Pereira , Felipe Lucas Marques de Souza , Simone Coutinho Cardoso , Luiz Antonio Ribeiro da Rosa
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引用次数: 0

摘要

这项工作的目的是评估插入拟人化模型中的 TLD 对强迫症治疗的反应,其中考虑到了伽马刀 Perfexion™ 设备的规划方法、平面等剂量投影尺寸、探测器尺寸、患者定位系统机械运动的不确定性、剂量计算算法和剂量率。对脑干的剂量以及发生脱发的可能性进行了评估。考虑到内囊区域的剂量测定,所看到的差异在方法误差范围之内。由于治疗强迫症,测得的脑干剂量低于相关限值。然而,在头皮区域观察到的剂量值高于确定脱发的理想极限值。结果表明,有可能建立一种方法,利用 TLD 来确定强迫症治疗计划的特征。
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Dose assessment by TL dosimetry according to parameters used in treatment plans for obsessive compulsive disorder using the Gamma Knife@ Perfexion™ device

The objective of this work was to assess the response of TLDs inserted in an anthropomorphic phantom for an OCD treatment considering the planning methodologies, dimensions of an isodose projection in a plan, detector dimensions, uncertainty of mechanical movement of the patient positioning system, dose calculation algorithms and dose rate in Gamma Knife Perfexion™ equipment. The doses to the brainstem were evaluated as well as the possibility of alopecia occurrence. Considering the dosimetry of the internal capsule region, differences seen were within the error of the method. The measured doses to the brainstem, due to the treatment of OCD, were lower than the limits considered relevant. However, for the scalp region, dose values, higher than the desirable limiting ones to determine alopecia were observed. Results showed that it is possible to establish a methodology that allows characterizing a treatment plan of OCD using TLDs.

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来源期刊
Radiation Measurements
Radiation Measurements 工程技术-核科学技术
CiteScore
4.10
自引率
20.00%
发文量
116
审稿时长
48 days
期刊介绍: The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.
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