3,6-Disubstituted derivatives of 1,2,4,5-tetrazine with pyridinyl amidine moieties and condensed systems on their basis: synthesis, docking, and antibacterial activity

New 3,6-disubstituted 1,2,4,5-tetrazine derivatives with pyridyl-substituted amidine moieties, as well as [1,2,4]triazolo[1,5-b][1,2,4,5-tetrazines and bis[1,2,4]triazolo-[1,5-b:1,5-f][1,2,4,5]tetrazines on their basis were synthesized. The obtained compounds were screened for activity against Neisseria gonorrhoeae and Mycobacterium tuberculosis. Compounds with pronounced antibacterial activity were detected. Docking was performed to determine a possible antibacterial effect of the compounds.