管理自身免疫性疾病患者的心血管风险:从营养角度看问题。

IF 4.6 3区 医学 Q1 NUTRITION & DIETETICS Current Nutrition Reports Pub Date : 2024-12-01 Epub Date: 2024-07-30 DOI:10.1007/s13668-024-00563-7
Huimin Chen, Lu Liu, Yi Wang, Liqiong Hong, Jiahui Pan, Xiongkai Yu, Haijiang Dai
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引用次数: 0

摘要

综述的目的:自身免疫性疾病表现为针对内源性抗原的免疫系统反应,对相当一部分人群产生重大影响。值得注意的是,心血管疾病(CVD)是导致发病率和死亡率的主要因素。耐人寻味的是,与普通人群相比,自身免疫性疾病患者的心血管疾病发病率更高。由于目前还没有解决这一难题的标准化方案,因此对心血管疾病风险因素进行细致的管理就显得尤为重要。本综述试图从营养学的角度来应对这一挑战:新的证据表明,炎症是自身免疫性疾病的一个共同点,在心血管疾病的发病机制中也起着关键作用。旨在减少炎症的营养干预措施在降低心血管风险方面已初见成效。将营养策略纳入自身免疫性疾病患者的治疗计划为降低心血管风险提供了一种综合方法。虽然传统的药物治疗仍然是基础,但增加有针对性的饮食干预措施可以为改善心血管预后提供补充途径。
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Managing Cardiovascular Risk in Patients with Autoimmune Diseases: Insights from a Nutritional Perspective.

Purpose of review: Autoimmune diseases manifest as an immune system response directed against endogenous antigens, exerting a significant influence on a substantial portion of the population. Notably, a leading contributor to morbidity and mortality in this context is cardiovascular disease (CVD). Intriguingly, individuals with autoimmune disorders exhibit a heightened prevalence of CVD compared to the general population. The meticulous management of CV risk factors assumes paramount importance, given the current absence of a standardized solution to this perplexity. This review endeavors to address this challenge from a nutritional perspective.

Recent findings: Emerging evidence suggests that inflammation, a common thread in autoimmune diseases, also plays a pivotal role in the pathogenesis of CVD. Nutritional interventions aimed at reducing inflammation have shown promise in mitigating cardiovascular risk. The integration of nutritional strategies into the management plans for patients with autoimmune diseases offers a holistic approach to reducing cardiovascular risk. While conventional pharmacological treatments remain foundational, the addition of targeted dietary interventions can provide a complementary pathway to improve cardiovascular outcomes.

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来源期刊
Current Nutrition Reports
Current Nutrition Reports Agricultural and Biological Sciences-Food Science
CiteScore
7.70
自引率
2.00%
发文量
59
期刊介绍: This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.
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