嗅沟巨型单发纤维瘤。不寻常位置的不寻常模拟器。

Fernando García Pérez , Ascensión Contreras Jiménez , Beatriz Agredano Ávila , José Masegosa González
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摘要

孤立性纤维瘤是一种罕见的间叶肿瘤,可发生在身体的任何部位,颅内的孤立性纤维瘤通常会与脑膜瘤相混淆。本病例是一名 57 岁的男性,因双额叶头痛、嗅觉障碍和行为改变而转诊至我院,病程长达 6 个月。放射学检查显示,患者颅前窝存在一个轴外外观的巨大肿瘤肿块,初步诊断为嗅沟巨大脑膜瘤。医生对肿块进行了全切。病理诊断出乎意料:单发纤维瘤(世卫组织 1 级,2021 年)。鉴于此类病变具有侵袭性,容易复发、恶变甚至转移,因此应首先选择大体上完全切除的手术治疗。术后应进行密切的临床和放射学随访。
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Giant solitary fibrous tumor of the olfactory groove. An unusual simulator in an unusual location
Solitary fibrous tumors are rare mesenchymal neoplasms that can develop in any part of the body, with those that settle intracranially being confused with meningiomas as a general rule. We present the case of a 57-year-old man referred to our hospital due to bifrontal headache, anosmia, and behavioral alterations of 6 months' duration. Radiological studies revealed the existence of a large tumor mass with an extra-axial appearance and location in the anterior cranial fossa, initially compatible with a giant meningioma of the olfactory groove. Gross total resection of the mass was carried out. The pathological diagnosis was unexpected: a solitary fibrous tumor (WHO grade 1, 2021). Given the aggressive nature of these lesions, with a tendency to recurrence, malignant transformation and even metastasis, surgery with macroscopically complete resection intention should constitute the first therapeutic option. Close clinical-radiological follow-up after the procedure is justified.
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