二十亿人感染:测量潜伏弓形虫病及其经济后果的低成本方法

Anja Achtziger, ‡. CarlosAl´os-Ferrer, §. MicheleGaragnani
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引用次数: 0

摘要

全世界有 20 多亿人感染了影响人类行为和认知的弓形虫。标准的诊断方法需要进行昂贵的医学检测,这阻碍了检测的普及,也阻碍了对感染影响的研究。我们提出并验证了一种利用响应时间和有限混合物模型对潜伏弓形虫感染进行诊断的廉价且易于使用的方法。一项临床研究表明,该方法灵敏而准确。英国一项具有代表性的大型研究表明,弓形虫感染在经济(年收入和就业率下降)和行为(危险行为、压力和抑郁增加)两方面都会造成相关和普遍的后果。
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Two Billion Infected: An Inexpensive Method to Measure Latent Toxoplasmosis and its Economic Consequences
Over two billion people worldwide are infected with the protozoan Toxoplasma gondii, which influences human behavior and cognition. Standard diagnosis methods involve costly medical tests, which prevents widespread testing and hinders the study of the infection's effects. We propose and validate an inexpensive and easy-to deploy diagnostic method for latent Toxoplasmosis infections using response times and finite-mixture models. A clinical study showed that the method is sensitive and accurate. A large, representative UK study showed that the infection's consequences are relevant and pervasive, both economically (decrease in yearly income and employment) and behaviorally (increase in risky behaviors, stress, and depression).
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