关于口腔黏膜疾病的热点问题:病例系列与回顾

Durba Roychowdhury, Rudra Prasad Chatterjee, S. Mahmud, Sudeshna Bagchi, Arunit Chatterjee
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摘要

口腔类苔藓样反应(OLR)是口腔黏膜的一种慢性炎症病变,是对某些牙科材料、药物和全身性疾病的过敏反应。据记载,OLR 在普通人群中的发病率非常低。OLR 的临床和组织学特征与口腔扁平苔藓(OLP)非常相似,因此在临床上很难将两者区分开来。与 OLP 相比,OLR 的恶变可能性更高。口腔扁平苔藓的诊断和治疗非常关键,因为误诊可能会对患者的生物物理健康造成不利影响。在此,我们介绍了两名患者的病例系列,他们都有汞合金修复体,并且在进食辛辣食物时出现颊粘膜烧灼感。经免疫组织病理学评估,确诊为口腔扁平苔藓样反应。消除致病因素仍是治疗的主要方法,这明显减轻了患者的痛苦,效果值得称赞。
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A Burning Issue on Oral Mucosal Diseases: Case Series with Review
Oral Lichenoid Reaction (OLR) is a chronic inflammatory lesion of the oral mucosa that occurs as an allergic response to certain dental materials, medications and systemic diseases. The frequency of OLR in the general population has been documented to be very less. The clinical and histological features of OLR closely resemble those of Oral Lichen Planus (OLP), making it challenging to distinguish between the two clinically. OLRs might have a higher malignant potential than OLP. The diagnosis and treatment of OLR is very crucial as misdiagnosis may result in detrimental effects on the biophysical health of the patient. Here, we present case series of two patients who presented with amalgam restorations and burning sensation on the buccal mucosa while consumption of hot and spicy food. An immunohistopathological evaluation confirmed the diagnosis as Oral Lichenoid Reaction. Elimination of causative factors remain the mainstay of treatment which markedly reduces the sufferings of the patient with a commendable result.
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