佐贺叶提取物(Abrus precatorius Linn)作为根管灌注替代材料对抑制粪肠球菌生长的影响

Pitri Ayu Puspita Sari, V. Sugiaman, Rudy Djuanda
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引用次数: 0

摘要

目的 本研究旨在探讨佐贺叶提取物对导致根管治疗失败的粪肠球菌的抗菌效果。材料与方法 本研究采用实验室实验法,使用浓度分别为 3.125、6.25、12.5、25、50 和 100%的萨迦叶提取物。2%的洗必泰作为阳性对照,100%的二甲亚砜作为阴性对照。抑制区的直径采用井扩散试验法进行测量。通过正态性检验(Shapiro-Wilk)、同质性检验(Levene)、参数检验(单因素方差分析)和进一步检验(事后检验)获得抑菌区直径测量数据并进行统计检验。结果 本研究观察到的最大抑菌区直径为 9.46 毫米(浓度为 100%),但并不比阳性对照的 16.55 毫米大。研究数据根据戴维斯和斯托特抑菌区分类法进行分析。结论 本研究得出结论,沙加叶提取物对粪大肠杆菌的生长具有抗菌作用。
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Effect of Saga Leaf Extract (Abrus precatorius Linn) in Inhibiting Enterococcus faecalis Bacteria Growth as an Alternative Root Canal Irrigation Material
Objective This study aims to examine the antibacterial effect of saga leaf extract on Enterococcus faecalis bacteria, which causes root canal treatment failure. Materials and Methods This research was conducted using a laboratory experimental method with saga leaf extract at 3.125, 6.25, 12.5, 25, 50, and 100% concentrations. Two percent chlorhexidine acts as the positive control, and 100% dimethyl sulfoxide as the negative control. The diameter of the inhibition zones was measured using the well diffusion test method. Statistical Analysis Data from the measurement of inhibition zone diameter were obtained and tested statistically using the normality test (Shapiro–Wilk), homogeneity test (Levene), parametric test (one-way analysis of variance), and further test (post hoc test). Results The largest inhibition zone diameter observed in this study was 9.46 mm at 100% concentration; however, it was not bigger than the positive control, which was measured at 16.55 mm. The research data were analyzed based on the classification of Davis and Stout inhibition zones. Conclusion This study concludes that saga leaf extract has an antibacterial effect on the growth of E. faecalis bacteria.
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来源期刊
European Journal of General Dentistry
European Journal of General Dentistry Dentistry-Dentistry (all)
CiteScore
1.00
自引率
0.00%
发文量
21
期刊介绍: European Journal of General Dentistry (EJGD) is one of the leading open-access international dental journal within the field of Dentistry. The aim of EJGD is publishing novel and high-quality research papers, as well as to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. EJGD publishes articles on all disciplines of dentistry including the cariology, orthodontics, oral surgery, preventive dentistry, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research.Moreover, EJGD also publish the scientific researches evaluating the use of new biomaterials, new drugs and new methods for treatment of patients with different kinds of oral and maxillofacial diseases or defects, the diagnosis of oral and maxillofacial diseases with new methods, etc. Moreover, researches on the quality of life, psychological interventions, improving disease treatment outcomes, the prevention, diagnosis and management of cancer therapeutic complications, rehabilitation, palliative and end of life care, and support teamwork for cancer care and oral health care for old patients are also welcome. EJGD publishes research articles, case reports, reviews and comparison studies evaluating materials and methods in the all fields of related to dentistry.
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