Adam bin Husein, Sana Mhd. Fouad Seoudi, H. M. El-Damanhoury, Ibrahim Mahmood Aziz, E. A. Abou Neel
Objectives The aim of the study was to explore the potential effects of incorporating 5 and 10 wt% of TiO2-doped phosphate glass powder as fillers into the universal adhesive system. Materials and Methods Human permanent premolars and molars were used in the study. Five and 10 wt% of TiO2-doped phosphate glass powder as fillers were added into the universal adhesive system. Unmodified universal adhesive was used as control. The effects of the added filler in the universal adhesive were examined on hybrid layer formation at the resin composite and dentine interface (mesio-occlusal-distal [MOD] cavities) under scanning electron microscope (SEM), shear bond strength (SBS) of resin composite to dentine using shear bond testing machine, and the patterns of fracture at the resin composite–dentin interface, which were examined under stereomicroscope. The SBS analyses were performed with (8 samples per group, n = 24) and without (8 samples per group, n = 24) 5,000 cycles of thermocycling. Statistical Analysis One-way analysis of variance (ANOVA) was used to analyze the data of the SBS. For bond strength, the effects of adding fillers into the universal adhesive were analyzed. Results The SEM images showed that the hybrid layers were similar in all the groups of unmodified and modified adhesives. An ANOVA test revealed that the SBSs of control and modified adhesives were not significantly different before (p = 0.15) or after (p = 0.39) thermocycling for all the groups. The patterns of fracture revealed various types of fracture in all adhesive groups including composite resin, adhesive, and dentine failure. Composite resin fractures are the most encountered pattern of fracture. Conclusion Adding 5 and 10 wt% of TiO2 into universal adhesive did not adversely affect the hybrid layer, SBS, or mode of failure of composite resin to dentine. The pattern of fracture at the resin composite and dentine interface showed a favorable bonding with more cohesive than adhesive failure, particularly with the 5 wt% glass-modified adhesive group.
{"title":"Hybrid Layer, Shear Bond Strength, and Fracture Patterns of Titanium Dioxide–Doped Phosphate Glass–Filled Universal Dental Adhesives","authors":"Adam bin Husein, Sana Mhd. Fouad Seoudi, H. M. El-Damanhoury, Ibrahim Mahmood Aziz, E. A. Abou Neel","doi":"10.1055/s-0044-1787789","DOIUrl":"https://doi.org/10.1055/s-0044-1787789","url":null,"abstract":"\u0000 Objectives The aim of the study was to explore the potential effects of incorporating 5 and 10 wt% of TiO2-doped phosphate glass powder as fillers into the universal adhesive system.\u0000 Materials and Methods Human permanent premolars and molars were used in the study. Five and 10 wt% of TiO2-doped phosphate glass powder as fillers were added into the universal adhesive system. Unmodified universal adhesive was used as control. The effects of the added filler in the universal adhesive were examined on hybrid layer formation at the resin composite and dentine interface (mesio-occlusal-distal [MOD] cavities) under scanning electron microscope (SEM), shear bond strength (SBS) of resin composite to dentine using shear bond testing machine, and the patterns of fracture at the resin composite–dentin interface, which were examined under stereomicroscope. The SBS analyses were performed with (8 samples per group, n = 24) and without (8 samples per group, n = 24) 5,000 cycles of thermocycling.\u0000 Statistical Analysis One-way analysis of variance (ANOVA) was used to analyze the data of the SBS. For bond strength, the effects of adding fillers into the universal adhesive were analyzed.\u0000 Results The SEM images showed that the hybrid layers were similar in all the groups of unmodified and modified adhesives. An ANOVA test revealed that the SBSs of control and modified adhesives were not significantly different before (p = 0.15) or after (p = 0.39) thermocycling for all the groups. The patterns of fracture revealed various types of fracture in all adhesive groups including composite resin, adhesive, and dentine failure. Composite resin fractures are the most encountered pattern of fracture.\u0000 Conclusion Adding 5 and 10 wt% of TiO2 into universal adhesive did not adversely affect the hybrid layer, SBS, or mode of failure of composite resin to dentine. The pattern of fracture at the resin composite and dentine interface showed a favorable bonding with more cohesive than adhesive failure, particularly with the 5 wt% glass-modified adhesive group.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"16 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141808939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dini Asrianti Bagio, Ibramanto Warganegara, I. Maharti, A. Margono, C. Kusumasari, S. Alinda, Valeria Widita Wairooy
Objective The American Association of Endodontists recommends the use of calcium hydroxide (Ca(OH)2) or triple antibiotic paste (TAP) as preferred medicaments in regenerative endodontic treatment. Although both medicaments showed an excellent antibacterial property, their impact on the viability of human dental pulp stem cells (hDPSCs) when used in combination remains uncertain. Previous studies have indicated that at certain concentrations, both Ca(OH)2 and TAP can be harmful to cells. Therefore, it is aimed to assess the effects of Ca(OH)2, TAP, and their combined application on the viability of hDPSCs in this study. Materials and Methods Primary cultured hDPSCs, reaching 80% confluency and at passages 3rd to 4th, were subjected to 24-hour starvation. Subsequently, they were cultured in media supplemented with Ca(OH)2, TAP at 0.1 and 1 mg/mL concentrations, and a combination of Ca(OH)2 and TAP at equivalent concentrations, with Dulbecco's modified eagle medium serving as the control group. The viability and morphology of hDPSCs were assessed using both the quantitative 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and qualitative 4',6-diamidino-2-phenylindole staining. Statistical Analysis First, the data were analyzed by one-way analysis of variance, followed by Bonferroni post hoc to compare between groups. All the tests were conducted at a significance level of 95% (p < 0.05). Results In this study, a notable variation in hDPSCs viability was observed among all groups, with the lowest viability recorded in the combination of Ca(OH)2 + TAP at 1 mg/mL (p < 0.05). Conclusion Ca(OH)2, TAP, and their combination are not toxic to hDPSCs and the use of their combination was superior in hDPSCs viability on Ca(OH)2 + TAP in the 0.1 mg/mL group.
目的 美国牙髓病学家协会推荐在牙髓再生治疗中使用氢氧化钙（Ca（OH）2）或三联抗生素糊剂（TAP）作为首选药物。虽然这两种药物都具有出色的抗菌性能，但它们联合使用时对人牙髓干细胞（hDPSCs）活力的影响仍不确定。以往的研究表明，在一定浓度下，Ca（OH）2 和 TAP 都会对细胞造成伤害。因此，本研究旨在评估 Ca（OH）2、TAP 及其联合应用对 hDPSCs 活力的影响。材料和方法 对原代培养的 hDPSCs（达到 80% 汇合度，第 3 至第 4 代）进行 24 小时饥饿。然后，将其置于添加了 Ca（OH）2、0.1 和 1 mg/mL 浓度的 TAP 以及同等浓度的 Ca（OH）2 和 TAP 组合的培养基中培养，并以杜氏改良鹰培养基作为对照组。采用 3-（4,5-二甲基噻唑-2-基）-2,5-二苯基溴化四氮唑定量检测法和 4',6-二脒基-2-苯基吲哚定性染色法评估 hDPSCs 的活力和形态。统计分析 首先，对数据进行单因素方差分析，然后用 Bonferroni post hoc 方法进行组间比较。所有检验的显著性水平均为 95%（P < 0.05）。结果 在这项研究中，所有组间的 hDPSCs 存活率都有显著差异，其中 Ca(OH)2 + TAP 组合（浓度为 1 mg/mL）的存活率最低（p < 0.05）。结论 Ca（OH）2、TAP 及其组合对 hDPSCs 没有毒性，在 0.1 mg/mL 组中，使用 Ca（OH）2 + TAP 组合对 hDPSCs 的存活率更有利。
{"title":"Assessing Cell Viability: Comparative Analysis of Calcium Hydroxide, Triple Antibiotic Paste, and Their Synergistic Impact on human Dental Pulp Stem Cells","authors":"Dini Asrianti Bagio, Ibramanto Warganegara, I. Maharti, A. Margono, C. Kusumasari, S. Alinda, Valeria Widita Wairooy","doi":"10.1055/s-0044-1788041","DOIUrl":"https://doi.org/10.1055/s-0044-1788041","url":null,"abstract":"\u0000 Objective The American Association of Endodontists recommends the use of calcium hydroxide (Ca(OH)2) or triple antibiotic paste (TAP) as preferred medicaments in regenerative endodontic treatment. Although both medicaments showed an excellent antibacterial property, their impact on the viability of human dental pulp stem cells (hDPSCs) when used in combination remains uncertain. Previous studies have indicated that at certain concentrations, both Ca(OH)2 and TAP can be harmful to cells. Therefore, it is aimed to assess the effects of Ca(OH)2, TAP, and their combined application on the viability of hDPSCs in this study.\u0000 Materials and Methods Primary cultured hDPSCs, reaching 80% confluency and at passages 3rd to 4th, were subjected to 24-hour starvation. Subsequently, they were cultured in media supplemented with Ca(OH)2, TAP at 0.1 and 1 mg/mL concentrations, and a combination of Ca(OH)2 and TAP at equivalent concentrations, with Dulbecco's modified eagle medium serving as the control group. The viability and morphology of hDPSCs were assessed using both the quantitative 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and qualitative 4',6-diamidino-2-phenylindole staining.\u0000 Statistical Analysis First, the data were analyzed by one-way analysis of variance, followed by Bonferroni post hoc to compare between groups. All the tests were conducted at a significance level of 95% (p < 0.05).\u0000 Results In this study, a notable variation in hDPSCs viability was observed among all groups, with the lowest viability recorded in the combination of Ca(OH)2 + TAP at 1 mg/mL (p < 0.05).\u0000 Conclusion Ca(OH)2, TAP, and their combination are not toxic to hDPSCs and the use of their combination was superior in hDPSCs viability on Ca(OH)2 + TAP in the 0.1 mg/mL group.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"38 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective This study aims to examine the antibacterial effect of saga leaf extract on Enterococcus faecalis bacteria, which causes root canal treatment failure. Materials and Methods This research was conducted using a laboratory experimental method with saga leaf extract at 3.125, 6.25, 12.5, 25, 50, and 100% concentrations. Two percent chlorhexidine acts as the positive control, and 100% dimethyl sulfoxide as the negative control. The diameter of the inhibition zones was measured using the well diffusion test method. Statistical Analysis Data from the measurement of inhibition zone diameter were obtained and tested statistically using the normality test (Shapiro–Wilk), homogeneity test (Levene), parametric test (one-way analysis of variance), and further test (post hoc test). Results The largest inhibition zone diameter observed in this study was 9.46 mm at 100% concentration; however, it was not bigger than the positive control, which was measured at 16.55 mm. The research data were analyzed based on the classification of Davis and Stout inhibition zones. Conclusion This study concludes that saga leaf extract has an antibacterial effect on the growth of E. faecalis bacteria.
{"title":"Effect of Saga Leaf Extract (Abrus precatorius Linn) in Inhibiting Enterococcus faecalis Bacteria Growth as an Alternative Root Canal Irrigation Material","authors":"Pitri Ayu Puspita Sari, V. Sugiaman, Rudy Djuanda","doi":"10.1055/s-0044-1788258","DOIUrl":"https://doi.org/10.1055/s-0044-1788258","url":null,"abstract":"\u0000 Objective This study aims to examine the antibacterial effect of saga leaf extract on Enterococcus faecalis bacteria, which causes root canal treatment failure.\u0000 Materials and Methods This research was conducted using a laboratory experimental method with saga leaf extract at 3.125, 6.25, 12.5, 25, 50, and 100% concentrations. Two percent chlorhexidine acts as the positive control, and 100% dimethyl sulfoxide as the negative control. The diameter of the inhibition zones was measured using the well diffusion test method.\u0000 Statistical Analysis Data from the measurement of inhibition zone diameter were obtained and tested statistically using the normality test (Shapiro–Wilk), homogeneity test (Levene), parametric test (one-way analysis of variance), and further test (post hoc test).\u0000 Results The largest inhibition zone diameter observed in this study was 9.46 mm at 100% concentration; however, it was not bigger than the positive control, which was measured at 16.55 mm. The research data were analyzed based on the classification of Davis and Stout inhibition zones.\u0000 Conclusion This study concludes that saga leaf extract has an antibacterial effect on the growth of E. faecalis bacteria.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"51 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141807043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. K. Yadalam, R. V. Anegundi, Ramya Ramadoss, Deepti Shrivastava, Awsaf Murdhi Alruwaili, Muhammad Faheemuddin, K. Srivastava
Objective Natural wingless-related integration site (Wnt) pathway antagonist sclerostin (SOST) has attracted much attention because unusual bone illnesses characterized by the increased bone mass result from its absence of action. The Wnt ligand is prevented from attaching to the Frizzled family receptor when SOST is present. In the active destruction complex, -catenin is phosphorylated. -Catenin molecules do not enter the nucleus and are broken down by a proteasome. As a result, Wnt-responsive genes are not activated, which lowers bone formation and raises bone resorption. A humanized monoclonal antibody called romosozumab binds to and inhibits SOST with significant cardiac side effects. As a result, the current study's objective is to find and screen Food and Drug Administration (FDA) medications that target SOST. Materials and Methods SOST's structure was retrieved from Protein Data Bank (PDB) (ID: 6l6r). Pharmacophore modeling and molecular operating environment-based virtual testing of FDA-approved medicines. Using the Desmond program, docking and molecular dynamics simulations were performed. Results Our findings revealed medications with FDA approval (ZINC000253387843) Amphotericin B. The stability and receptor–ligand interactions are pretty substantial, as demonstrated by the findings of docking and Molecular dynamics simulations, which have a docking score of −7.3 k/mol and root mean square deviation stability at 40 nanoseconds, respectively. Conclusion The suggested pharmacological therapy shows promise since it uses the Wnt pathway to target the primary bone formation mechanism. However, additional prospective studies are required to apply the available data to clinical practice.
目的 天然无翼鸟相关整合位点（Wnt）通路拮抗剂硬骨素（SOST）引起了人们的广泛关注，因为如果没有它的作用，就会导致以骨量增加为特征的不寻常骨病。当 SOST 存在时，Wnt 配体无法附着到 Frizzled 家族受体上。在活性破坏复合物中，-catenin 被磷酸化。-catenin分子不会进入细胞核，而是被蛋白酶体分解。因此，Wnt 反应基因不会被激活，从而降低了骨形成，增加了骨吸收。一种名为romosozumab的人源化单克隆抗体能与SOST结合并对其产生抑制作用，但会对心脏产生明显的副作用。因此，本研究的目的是寻找和筛选针对 SOST 的食品药品管理局（FDA）药物。材料与方法 从蛋白质数据库（PDB）检索到 SOST 的结构（ID：6l6r）。药理模型和基于分子操作环境的 FDA 批准药物虚拟测试。使用 Desmond 程序进行了对接和分子动力学模拟。结果 我们的研究结果表明，获得 FDA 批准的药物（ZINC000253387843）两性霉素 B 的稳定性和受体配体之间的相互作用相当可观，对接和分子动力学模拟的结果也证明了这一点，其对接得分分别为 -7.3 k/mol，均方根偏差稳定性为 40 纳秒。结论 建议的药理疗法利用 Wnt 通路针对主要的骨形成机制，因此前景看好。然而，要将现有数据应用于临床实践，还需要进行更多的前瞻性研究。
{"title":"Identification of Repurposed FDA Drugs by Targeting Sclerostin via the Wnt Pathway for Alveolar Bone Formation","authors":"P. K. Yadalam, R. V. Anegundi, Ramya Ramadoss, Deepti Shrivastava, Awsaf Murdhi Alruwaili, Muhammad Faheemuddin, K. Srivastava","doi":"10.1055/s-0043-1777841","DOIUrl":"https://doi.org/10.1055/s-0043-1777841","url":null,"abstract":"\u0000 Objective Natural wingless-related integration site (Wnt) pathway antagonist sclerostin (SOST) has attracted much attention because unusual bone illnesses characterized by the increased bone mass result from its absence of action. The Wnt ligand is prevented from attaching to the Frizzled family receptor when SOST is present. In the active destruction complex, -catenin is phosphorylated. -Catenin molecules do not enter the nucleus and are broken down by a proteasome. As a result, Wnt-responsive genes are not activated, which lowers bone formation and raises bone resorption. A humanized monoclonal antibody called romosozumab binds to and inhibits SOST with significant cardiac side effects. As a result, the current study's objective is to find and screen Food and Drug Administration (FDA) medications that target SOST.\u0000 Materials and Methods SOST's structure was retrieved from Protein Data Bank (PDB) (ID: 6l6r). Pharmacophore modeling and molecular operating environment-based virtual testing of FDA-approved medicines. Using the Desmond program, docking and molecular dynamics simulations were performed.\u0000 Results Our findings revealed medications with FDA approval (ZINC000253387843) Amphotericin B. The stability and receptor–ligand interactions are pretty substantial, as demonstrated by the findings of docking and Molecular dynamics simulations, which have a docking score of −7.3 k/mol and root mean square deviation stability at 40 nanoseconds, respectively.\u0000 Conclusion The suggested pharmacological therapy shows promise since it uses the Wnt pathway to target the primary bone formation mechanism. However, additional prospective studies are required to apply the available data to clinical practice.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"15 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. S. Bharadwaj, S. Kalgeri, A. Shivakumar, V. Doddawad, P. M. Shankar, Sunil Kumar B. B.
The present scenario caused by the coronavirus disease 2019 pandemic—and the recession in the dental industry—a newer approach modality is on every dentist's mind. As the future is always questionable in the present situation, we can expect remarkable changes in the dental field, which will revolutionize dental health care facilities worldwide. Several upcoming trends are introduced every year. Recent studies demonstrate that in the future dental field will be presented with exciting new technologies, improved business practices, and novel ways to optimize patient experience, and even nanorobotic dentistry will be in practice.Future dentistry is expected to have more innovation as it is adopting the latest technologies and facilitating the growth of global dentistry. This is because the increasing frequency of the treatment of dental disorders and related risk factors, combined with the introduction of advanced technology will be some of the major factors driving technological growth over the next few years.This article communicates the newer changes taking place in dentistry which will have an impact on the future dental field.
{"title":"Revolutionizing Dental Health Care: An In-Depth Exploration of Technological Advancements","authors":"R. S. Bharadwaj, S. Kalgeri, A. Shivakumar, V. Doddawad, P. M. Shankar, Sunil Kumar B. B.","doi":"10.1055/s-0043-1776321","DOIUrl":"https://doi.org/10.1055/s-0043-1776321","url":null,"abstract":"The present scenario caused by the coronavirus disease 2019 pandemic—and the recession in the dental industry—a newer approach modality is on every dentist's mind. As the future is always questionable in the present situation, we can expect remarkable changes in the dental field, which will revolutionize dental health care facilities worldwide. Several upcoming trends are introduced every year. Recent studies demonstrate that in the future dental field will be presented with exciting new technologies, improved business practices, and novel ways to optimize patient experience, and even nanorobotic dentistry will be in practice.Future dentistry is expected to have more innovation as it is adopting the latest technologies and facilitating the growth of global dentistry. This is because the increasing frequency of the treatment of dental disorders and related risk factors, combined with the introduction of advanced technology will be some of the major factors driving technological growth over the next few years.This article communicates the newer changes taking place in dentistry which will have an impact on the future dental field.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"398 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139834368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. S. Bharadwaj, S. Kalgeri, A. Shivakumar, V. Doddawad, P. M. Shankar, Sunil Kumar B. B.
The present scenario caused by the coronavirus disease 2019 pandemic—and the recession in the dental industry—a newer approach modality is on every dentist's mind. As the future is always questionable in the present situation, we can expect remarkable changes in the dental field, which will revolutionize dental health care facilities worldwide. Several upcoming trends are introduced every year. Recent studies demonstrate that in the future dental field will be presented with exciting new technologies, improved business practices, and novel ways to optimize patient experience, and even nanorobotic dentistry will be in practice.Future dentistry is expected to have more innovation as it is adopting the latest technologies and facilitating the growth of global dentistry. This is because the increasing frequency of the treatment of dental disorders and related risk factors, combined with the introduction of advanced technology will be some of the major factors driving technological growth over the next few years.This article communicates the newer changes taking place in dentistry which will have an impact on the future dental field.
{"title":"Revolutionizing Dental Health Care: An In-Depth Exploration of Technological Advancements","authors":"R. S. Bharadwaj, S. Kalgeri, A. Shivakumar, V. Doddawad, P. M. Shankar, Sunil Kumar B. B.","doi":"10.1055/s-0043-1776321","DOIUrl":"https://doi.org/10.1055/s-0043-1776321","url":null,"abstract":"The present scenario caused by the coronavirus disease 2019 pandemic—and the recession in the dental industry—a newer approach modality is on every dentist's mind. As the future is always questionable in the present situation, we can expect remarkable changes in the dental field, which will revolutionize dental health care facilities worldwide. Several upcoming trends are introduced every year. Recent studies demonstrate that in the future dental field will be presented with exciting new technologies, improved business practices, and novel ways to optimize patient experience, and even nanorobotic dentistry will be in practice.Future dentistry is expected to have more innovation as it is adopting the latest technologies and facilitating the growth of global dentistry. This is because the increasing frequency of the treatment of dental disorders and related risk factors, combined with the introduction of advanced technology will be some of the major factors driving technological growth over the next few years.This article communicates the newer changes taking place in dentistry which will have an impact on the future dental field.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"8 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139774620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Abdel-Halim Abdel-Azim Hassan, A. Sindi, Abeer Mohamed Atout, Mohamed S. M. Morsy, K. Mattoo, Vishnu Teja Obulareddy, Ankita Mathur, Vini Mehta
Objectives A comparable performance between bulk-fill composites (BFCs) and progressively inserted conventional resin composite (CRC) has been observed in previous studies. However, a significant number of dental institutions in India continue to employ incremental techniques for RC restorations during preclinical studies. But as BFCs are gaining popularity, they may soon be a part of the curriculum for dental students. The aim of this study was to assess the microhardness and the polymerization efficiency of bulk-fill composites versus CRC in class II slot preparations restored by second-year dental students on ivorine mandibular first molar teeth with high-intensity (HI) and low-intensity (LI) light-curing units using the standard mesial slot preparation technique. Material and Methods Fifty preclinical dental students of second year of a dental college were recruited for the study on a voluntary basis. During their preclinical instructions, all participants were taught and made to practice the handling and curing techniques for two-surface RC restorations for 4 months. Each student was asked to perform four RC restorations: CRC-HI, CRC-LI, BFC-HI, and BFC LI. Assessment of microhardness was done using the Vickers microhardness (VMH) test. Statistical analysis One-way and multivariate analysis of variance and Bonferroni 's post hoc test tests were used for data analysis. Results The results showed a significant decrease in the VMH readings in the horizontal axis, progressing from the uppermost to the lowermost positions (p > 0.05). In all the examined groups, the VMH values at the deepest reading locations were found to be higher than 80% of the values observed at the occlusal surface reading locations. Statistically significant associations were seen between the RC type and the light source used in the VMH readings conducted (p > 0.05). However, no significant correlation was identified between the type of light source and the vertical VMH readings (p > 0.05). Conclusion Instructing dental students to place RC restorations using CRC or BFC materials together with both HI and LI light-curing protocols is safe and can be considered for preclinical studies.
{"title":"Assessment of Microhardness of Bulk-Fill Class II Resin Composite Restorations Performed by Preclinical Students: An In Vitro Study","authors":"Ali Abdel-Halim Abdel-Azim Hassan, A. Sindi, Abeer Mohamed Atout, Mohamed S. M. Morsy, K. Mattoo, Vishnu Teja Obulareddy, Ankita Mathur, Vini Mehta","doi":"10.1055/s-0043-1778675","DOIUrl":"https://doi.org/10.1055/s-0043-1778675","url":null,"abstract":"\u0000 Objectives A comparable performance between bulk-fill composites (BFCs) and progressively inserted conventional resin composite (CRC) has been observed in previous studies. However, a significant number of dental institutions in India continue to employ incremental techniques for RC restorations during preclinical studies. But as BFCs are gaining popularity, they may soon be a part of the curriculum for dental students. The aim of this study was to assess the microhardness and the polymerization efficiency of bulk-fill composites versus CRC in class II slot preparations restored by second-year dental students on ivorine mandibular first molar teeth with high-intensity (HI) and low-intensity (LI) light-curing units using the standard mesial slot preparation technique.\u0000 Material and Methods Fifty preclinical dental students of second year of a dental college were recruited for the study on a voluntary basis. During their preclinical instructions, all participants were taught and made to practice the handling and curing techniques for two-surface RC restorations for 4 months. Each student was asked to perform four RC restorations: CRC-HI, CRC-LI, BFC-HI, and BFC LI. Assessment of microhardness was done using the Vickers microhardness (VMH) test.\u0000 Statistical analysis One-way and multivariate analysis of variance and Bonferroni 's post hoc test tests were used for data analysis.\u0000 Results The results showed a significant decrease in the VMH readings in the horizontal axis, progressing from the uppermost to the lowermost positions (p > 0.05). In all the examined groups, the VMH values at the deepest reading locations were found to be higher than 80% of the values observed at the occlusal surface reading locations. Statistically significant associations were seen between the RC type and the light source used in the VMH readings conducted (p > 0.05). However, no significant correlation was identified between the type of light source and the vertical VMH readings (p > 0.05).\u0000 Conclusion Instructing dental students to place RC restorations using CRC or BFC materials together with both HI and LI light-curing protocols is safe and can be considered for preclinical studies.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"56 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139810978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nirupama Narayanan, Jennifer Sabour, Brian Chiswell, Mitch Weiland
Objective The purpose of our study was to evaluate plant-derived essential oils (EOs) as natural alternatives to commercial alcohol-based mouthwashes in the prevention of dental caries since several recent studies have linked high incidence of oral cancer among users with a history of prolonged use of alcohol-based mouthwashes. Materials and Methods Lemongrass, Citronella Java, Gingergrass, and Caraway seed EOs were tested against commonly occurring multidrug-resistant (MDR) oral bacteria namely Micrococcus luteus, Enterococcus faecalis, Streptococcus oralis, and Streptococcus salivarius. Agar well diffusion method was used to determine the antibacterial effectiveness of these EOs. Samples of Citronella Java and Lemongrass EO were also analyzed by gas chromatography (GC). Results Lemongrass and Citronella Java exhibited the highest antibacterial activity against all four bacterial strains. Inhibition zones of Lemongrass were 12, 21.3, 28.3, and 32 mm in diameter against E. faecalis, M. luteus, S. oralis, and S. salivarius, respectively. In comparison, inhibition zones of Citronella Java were 11.5, 17, 20.7, and 20.2 mm in diameter against E. faecalis, M. luteus, S. oralis, and S. salivarius, respectively. A significant finding in our study was that antibacterial activity of Lemongrass was much higher than that of tetracycline, a broad-spectrum antibiotic, against S. oralis and S. salivarius, while the inhibitory effects of Citronella Java against these two oral streptococci were comparable to tetracycline. The major components of Citronella Java identified by GC were citronellal, citronellol, and geraniol, whereas Lemongrass was primarily composed of cis and trans forms of citral. Conclusion Our results suggest that Lemongrass and Citronella Java could be promising natural alternatives to alcohol-based mouthwashes against MDR oral bacteria in the prevention of dental caries.
{"title":"Evaluation of Plant Essential Oils as Natural Alternatives for Alcohol-based Mouthwashes: Spotlight—Lemongrass and Citronella Java","authors":"Nirupama Narayanan, Jennifer Sabour, Brian Chiswell, Mitch Weiland","doi":"10.1055/s-0043-1777768","DOIUrl":"https://doi.org/10.1055/s-0043-1777768","url":null,"abstract":"\u0000 Objective The purpose of our study was to evaluate plant-derived essential oils (EOs) as natural alternatives to commercial alcohol-based mouthwashes in the prevention of dental caries since several recent studies have linked high incidence of oral cancer among users with a history of prolonged use of alcohol-based mouthwashes.\u0000 Materials and Methods Lemongrass, Citronella Java, Gingergrass, and Caraway seed EOs were tested against commonly occurring multidrug-resistant (MDR) oral bacteria namely Micrococcus luteus, Enterococcus faecalis, Streptococcus oralis, and Streptococcus salivarius. Agar well diffusion method was used to determine the antibacterial effectiveness of these EOs. Samples of Citronella Java and Lemongrass EO were also analyzed by gas chromatography (GC).\u0000 Results Lemongrass and Citronella Java exhibited the highest antibacterial activity against all four bacterial strains. Inhibition zones of Lemongrass were 12, 21.3, 28.3, and 32 mm in diameter against E. faecalis, M. luteus, S. oralis, and S. salivarius, respectively. In comparison, inhibition zones of Citronella Java were 11.5, 17, 20.7, and 20.2 mm in diameter against E. faecalis, M. luteus, S. oralis, and S. salivarius, respectively. A significant finding in our study was that antibacterial activity of Lemongrass was much higher than that of tetracycline, a broad-spectrum antibiotic, against S. oralis and S. salivarius, while the inhibitory effects of Citronella Java against these two oral streptococci were comparable to tetracycline. The major components of Citronella Java identified by GC were citronellal, citronellol, and geraniol, whereas Lemongrass was primarily composed of cis and trans forms of citral.\u0000 Conclusion Our results suggest that Lemongrass and Citronella Java could be promising natural alternatives to alcohol-based mouthwashes against MDR oral bacteria in the prevention of dental caries.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"41 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139871763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Abdel-Halim Abdel-Azim Hassan, A. Sindi, Abeer Mohamed Atout, Mohamed S. M. Morsy, K. Mattoo, Vishnu Teja Obulareddy, Ankita Mathur, Vini Mehta
Objectives A comparable performance between bulk-fill composites (BFCs) and progressively inserted conventional resin composite (CRC) has been observed in previous studies. However, a significant number of dental institutions in India continue to employ incremental techniques for RC restorations during preclinical studies. But as BFCs are gaining popularity, they may soon be a part of the curriculum for dental students. The aim of this study was to assess the microhardness and the polymerization efficiency of bulk-fill composites versus CRC in class II slot preparations restored by second-year dental students on ivorine mandibular first molar teeth with high-intensity (HI) and low-intensity (LI) light-curing units using the standard mesial slot preparation technique. Material and Methods Fifty preclinical dental students of second year of a dental college were recruited for the study on a voluntary basis. During their preclinical instructions, all participants were taught and made to practice the handling and curing techniques for two-surface RC restorations for 4 months. Each student was asked to perform four RC restorations: CRC-HI, CRC-LI, BFC-HI, and BFC LI. Assessment of microhardness was done using the Vickers microhardness (VMH) test. Statistical analysis One-way and multivariate analysis of variance and Bonferroni 's post hoc test tests were used for data analysis. Results The results showed a significant decrease in the VMH readings in the horizontal axis, progressing from the uppermost to the lowermost positions (p > 0.05). In all the examined groups, the VMH values at the deepest reading locations were found to be higher than 80% of the values observed at the occlusal surface reading locations. Statistically significant associations were seen between the RC type and the light source used in the VMH readings conducted (p > 0.05). However, no significant correlation was identified between the type of light source and the vertical VMH readings (p > 0.05). Conclusion Instructing dental students to place RC restorations using CRC or BFC materials together with both HI and LI light-curing protocols is safe and can be considered for preclinical studies.
{"title":"Assessment of Microhardness of Bulk-Fill Class II Resin Composite Restorations Performed by Preclinical Students: An In Vitro Study","authors":"Ali Abdel-Halim Abdel-Azim Hassan, A. Sindi, Abeer Mohamed Atout, Mohamed S. M. Morsy, K. Mattoo, Vishnu Teja Obulareddy, Ankita Mathur, Vini Mehta","doi":"10.1055/s-0043-1778675","DOIUrl":"https://doi.org/10.1055/s-0043-1778675","url":null,"abstract":"\u0000 Objectives A comparable performance between bulk-fill composites (BFCs) and progressively inserted conventional resin composite (CRC) has been observed in previous studies. However, a significant number of dental institutions in India continue to employ incremental techniques for RC restorations during preclinical studies. But as BFCs are gaining popularity, they may soon be a part of the curriculum for dental students. The aim of this study was to assess the microhardness and the polymerization efficiency of bulk-fill composites versus CRC in class II slot preparations restored by second-year dental students on ivorine mandibular first molar teeth with high-intensity (HI) and low-intensity (LI) light-curing units using the standard mesial slot preparation technique.\u0000 Material and Methods Fifty preclinical dental students of second year of a dental college were recruited for the study on a voluntary basis. During their preclinical instructions, all participants were taught and made to practice the handling and curing techniques for two-surface RC restorations for 4 months. Each student was asked to perform four RC restorations: CRC-HI, CRC-LI, BFC-HI, and BFC LI. Assessment of microhardness was done using the Vickers microhardness (VMH) test.\u0000 Statistical analysis One-way and multivariate analysis of variance and Bonferroni 's post hoc test tests were used for data analysis.\u0000 Results The results showed a significant decrease in the VMH readings in the horizontal axis, progressing from the uppermost to the lowermost positions (p > 0.05). In all the examined groups, the VMH values at the deepest reading locations were found to be higher than 80% of the values observed at the occlusal surface reading locations. Statistically significant associations were seen between the RC type and the light source used in the VMH readings conducted (p > 0.05). However, no significant correlation was identified between the type of light source and the vertical VMH readings (p > 0.05).\u0000 Conclusion Instructing dental students to place RC restorations using CRC or BFC materials together with both HI and LI light-curing protocols is safe and can be considered for preclinical studies.","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139870745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective The aim of this study was to measure the internal, marginal fitness, and trueness of a three-unit fixed zirconium bridge fabricated using two types of zirconia and different marginal cement space thicknesses. Methods and Materials Thirty-two aluminum master models, constructed by computer numerical control (CNC) milling machines using aluminum rod, representing two prepared aluminum abutments (the upper first premolar and the first molar) were chosen due to differences in shape and dimensions, which may affect adaptation. It may also be considered one of the most common cases in clinical practice and a missing second premolars were used to fabricate a three-unit fixed partial zirconium bridge. A master model was scanned with an intraoral scanner. Fixed dental prostheses (FDPs) were fabricated with two designs (single-layer high-translucent [HT] Katana and ultra-translucent multilayer (UTML] zirconia Katana) and two marginal cement space thicknesses (0 and 25μm for HT and ML). These specimens are divided according to marginal cement space and type of zirconia into four groups, each containing eight samples. Group A: 25-μm marginal cement space with single-layer HT zirconia. Group B: 25-μm marginal gap with UTML zirconia. Group C: 0 μm marginal gap single-layer HT zirconia. Group D: 0 μm marginal gap with UTML zirconia. Fitness and trueness of the fabricated three-unit FDPs were evaluated by scanning the silicone replica of the cement space and analyzing the thickness of the silicone replica in the three-dimensional inspection software (Geomagic Control X, Morrisville, North Carolina, USA). Results Highest mean value of internal gap was recorded at the molar abutment of group D (95.05, ± 3.42 μm), while the lowest was recorded at the premolar abutment of group A (57.12, ± 2.43μm). For marginal gap, the lowest marginal gap was also recorded at the premolar abutment of group A (36.14, ± 3.94μm), and the highest was at the molar abutment of group D (84.74, ± 2.98 μm).For trueness, group A showed the lowest root mean square (RMS) of mean with both abutments compared with group D, which recorded the highest RMS of mean for trueness. Conclusion The marginal cement space thickness affects the FPD internal, marginal fitness, and trueness; single-layer HT (Katana) zirconia shows better fitness and trueness than UTML (Katana).
{"title":"Digital Evaluation of the Trueness and Fitting Accuracy of a Three-Unit Fixed Zirconium Bridge Fabricated from Different Types of Zirconia and Different Marginal Cement Space Thickness","authors":"Mutaz Omran Mosa, Adel F. Ibraheem, H. Hussein","doi":"10.1055/s-0043-1777010","DOIUrl":"https://doi.org/10.1055/s-0043-1777010","url":null,"abstract":"\u0000 Objective The aim of this study was to measure the internal, marginal fitness, and trueness of a three-unit fixed zirconium bridge fabricated using two types of zirconia and different marginal cement space thicknesses.\u0000 Methods and Materials Thirty-two aluminum master models, constructed by computer numerical control (CNC) milling machines using aluminum rod, representing two prepared aluminum abutments (the upper first premolar and the first molar) were chosen due to differences in shape and dimensions, which may affect adaptation. It may also be considered one of the most common cases in clinical practice and a missing second premolars were used to fabricate a three-unit fixed partial zirconium bridge. A master model was scanned with an intraoral scanner. Fixed dental prostheses (FDPs) were fabricated with two designs (single-layer high-translucent [HT] Katana and ultra-translucent multilayer (UTML] zirconia Katana) and two marginal cement space thicknesses (0 and 25μm for HT and ML). These specimens are divided according to marginal cement space and type of zirconia into four groups, each containing eight samples. Group A: 25-μm marginal cement space with single-layer HT zirconia. Group B: 25-μm marginal gap with UTML zirconia. Group C: 0 μm marginal gap single-layer HT zirconia. Group D: 0 μm marginal gap with UTML zirconia. Fitness and trueness of the fabricated three-unit FDPs were evaluated by scanning the silicone replica of the cement space and analyzing the thickness of the silicone replica in the three-dimensional inspection software (Geomagic Control X, Morrisville, North Carolina, USA).\u0000 Results Highest mean value of internal gap was recorded at the molar abutment of group D (95.05, ± 3.42 μm), while the lowest was recorded at the premolar abutment of group A (57.12, ± 2.43μm). For marginal gap, the lowest marginal gap was also recorded at the premolar abutment of group A (36.14, ± 3.94μm), and the highest was at the molar abutment of group D (84.74, ± 2.98 μm).For trueness, group A showed the lowest root mean square (RMS) of mean with both abutments compared with group D, which recorded the highest RMS of mean for trueness.\u0000 Conclusion The marginal cement space thickness affects the FPD internal, marginal fitness, and trueness; single-layer HT (Katana) zirconia shows better fitness and trueness than UTML (Katana).","PeriodicalId":37771,"journal":{"name":"European Journal of General Dentistry","volume":"12 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140525011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：