{"title":"经修订的患者对取消处方的态度(rPATD)问卷:利用大型匿名数据库进行的调查","authors":"Marjorie Weiss, Rhian Deslandes, Louise Hughes","doi":"10.1093/jphsr/rmae014","DOIUrl":null,"url":null,"abstract":"\n \n \n Stopping or “deprescribing” one or more of a patient’s medications is a growing focus for clinical practice and health service research. A deprescribing questionnaire survey, the revised Patient’s Attitudes Towards Deprescribing (rPATD), has been developed and validated in Australia. The aim of this study was to explore the use of the rPATD in a large Welsh population.\n \n \n \n The rPATD was made available through HealthWise Wales, a platform that enables people in Wales to volunteer to participate in research. Questionnaire data were explored descriptively and using a confirmatory factor analysis (CFA) on the original four factors in the rPATD (Burden, Appropriateness, Concern, and Involvement).\n \n \n \n A total of 1759 patients completed questionnaires. The mean age was 58.6, each prescribed on average 3.69 medicines (range 1–34). In total 75.1% (1303/1735) agreed or strongly agreed that they would be willing to have a medicine deprescribed, if suggested by a doctor, and 19.0% (333/1749) would like to try stopping a medicine. A CFA was performed using maximum likelihood and showed a mediocre fit (RMSEA = 0.083). A Mann–Whitney U test revealed an association between feeling the burden of medicine taking or expressing a belief in the inappropriateness of their medication and a greater willingness to stop medicine if suggested by a doctor (BURDEN Z = −5.6, P≤.0001; appropriateness Z = −9.6, P≤.0001).\n \n \n \n Willingness to have a medicine deprescribed was lower than in previous research, likely due to a range of reported factors. The potential value of rPATD has been demonstrated for future UK-wide applications.\n","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The revised patient attitudes to deprescribing (rPATD) questionnaire: an investigation using a large anonymized database\",\"authors\":\"Marjorie Weiss, Rhian Deslandes, Louise Hughes\",\"doi\":\"10.1093/jphsr/rmae014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n \\n Stopping or “deprescribing” one or more of a patient’s medications is a growing focus for clinical practice and health service research. A deprescribing questionnaire survey, the revised Patient’s Attitudes Towards Deprescribing (rPATD), has been developed and validated in Australia. 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A Mann–Whitney U test revealed an association between feeling the burden of medicine taking or expressing a belief in the inappropriateness of their medication and a greater willingness to stop medicine if suggested by a doctor (BURDEN Z = −5.6, P≤.0001; appropriateness Z = −9.6, P≤.0001).\\n \\n \\n \\n Willingness to have a medicine deprescribed was lower than in previous research, likely due to a range of reported factors. 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引用次数: 0
摘要
停止或 "取消 "患者的一种或多种药物治疗是临床实践和医疗服务研究中日益关注的问题。澳大利亚开发并验证了一种停药问卷调查,即 "修订版患者对停药的态度"(rPATD)。本研究旨在探讨 rPATD 在大量威尔士人口中的使用情况。 rPATD 可通过威尔士健康智库(HealthWise Wales)获得,威尔士健康智库是一个让威尔士人自愿参与研究的平台。我们对问卷数据进行了描述性分析,并对 rPATD 的四个原始因子(负担、适当性、关注和参与)进行了确证因子分析 (CFA)。 共有 1759 名患者填写了问卷。平均年龄为 58.6 岁,每人平均处方 3.69 种药物(1-34 种不等)。总计有 75.1%(1303/1735)的患者同意或非常同意如果医生建议他们停药,他们愿意停药,19.0%(333/1749)的患者愿意尝试停药。使用最大似然法进行了 CFA 分析,结果显示拟合度一般(RMSEA = 0.083)。Mann-Whitney U 检验显示,感觉服药负担重或认为药物不合适与更愿意在医生建议下停药之间存在关联(负担 Z = -5.6,P≤.0001;合适 Z = -9.6,P≤.0001)。 与之前的研究相比,患者对处方药的意愿较低,这可能是由一系列报告因素造成的。rPATD 的潜在价值已在未来英国范围内的应用中得到证实。
The revised patient attitudes to deprescribing (rPATD) questionnaire: an investigation using a large anonymized database
Stopping or “deprescribing” one or more of a patient’s medications is a growing focus for clinical practice and health service research. A deprescribing questionnaire survey, the revised Patient’s Attitudes Towards Deprescribing (rPATD), has been developed and validated in Australia. The aim of this study was to explore the use of the rPATD in a large Welsh population.
The rPATD was made available through HealthWise Wales, a platform that enables people in Wales to volunteer to participate in research. Questionnaire data were explored descriptively and using a confirmatory factor analysis (CFA) on the original four factors in the rPATD (Burden, Appropriateness, Concern, and Involvement).
A total of 1759 patients completed questionnaires. The mean age was 58.6, each prescribed on average 3.69 medicines (range 1–34). In total 75.1% (1303/1735) agreed or strongly agreed that they would be willing to have a medicine deprescribed, if suggested by a doctor, and 19.0% (333/1749) would like to try stopping a medicine. A CFA was performed using maximum likelihood and showed a mediocre fit (RMSEA = 0.083). A Mann–Whitney U test revealed an association between feeling the burden of medicine taking or expressing a belief in the inappropriateness of their medication and a greater willingness to stop medicine if suggested by a doctor (BURDEN Z = −5.6, P≤.0001; appropriateness Z = −9.6, P≤.0001).
Willingness to have a medicine deprescribed was lower than in previous research, likely due to a range of reported factors. The potential value of rPATD has been demonstrated for future UK-wide applications.