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Effects of comprehensive medication review on opioid overuse among medicare beneficiaries. 综合药物审查对医疗保险受益人过度使用阿片类药物的影响。
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-02-28 eCollection Date: 2024-03-01 DOI: 10.1093/jphsr/rmae002
Yongbo Sim, Clayton F Hausberger, Junling Wang

Objectives: This study examined the effects of the comprehensive medication review of Medicare medication therapy management programs on opioid overuse among Medicare beneficiaries.

Methods: This retrospective study analyzed Medicare data from 2016 to 2017. The intervention group included Medicare beneficiaries who newly received comprehensive medication review in 2017; the control group referred to patients who met the general eligible criteria for the medication therapy management program but did not enroll in 2016 or 2017. Propensity score matching was performed to increase characteristic compatibility between the intervention and control groups. Three measures of opioid overuse were analyzed: use of opioids at a high dosage, use of opioids from multiple providers, and concurrent use of opioids and benzodiazepines. The effects of comprehensive medication review on opioid overuse were analyzed with a multivariate logistic regression with an interaction term between the receipt of comprehensive medication review and the year 2017.

Key findings: The proportion of concurrent use of opioids and benzodiazepines declined at a greater rate among the recipients (2.21%) than non-recipients (1.55%) of the comprehensive medication review. In the adjusted analysis, the odds ratio of no concurrent use of opioids and benzodiazepines was 5% higher (1.05; 95% confidence interval = 1.02-1.09) among recipients than non-recipients. These significant findings were not found for the other two measures of opioid overuse.

Conclusions: Comprehensive medication review is associated with reduced concurrent use of opioids and benzodiazepines among Medicare beneficiaries. Such service should be incorporated into the current approaches for addressing the opioid epidemic.

目的:本研究探讨了医疗保险药物治疗管理计划的综合药物审查对医疗保险受益人过度使用阿片类药物的影响:本研究探讨了医疗保险药物治疗管理项目的综合药物审查对医疗保险受益人过度使用阿片类药物的影响:这项回顾性研究分析了2016年至2017年的医疗保险数据。干预组包括2017年新接受综合药物审查的医疗保险受益人;对照组指符合药物治疗管理计划一般合格标准但在2016年或2017年未加入的患者。为增加干预组和对照组之间的特征匹配,进行了倾向得分匹配。分析了阿片类药物过度使用的三项指标:高剂量使用阿片类药物、从多个医疗机构使用阿片类药物以及同时使用阿片类药物和苯二氮卓类药物。通过多变量逻辑回归分析了综合用药审查对阿片类药物过度使用的影响,并在接受综合用药审查与2017年之间加入了交互项:与未接受综合用药审查者(1.55%)相比,接受综合用药审查者(2.21%)同时使用阿片类药物和苯二氮卓的比例下降幅度更大。在调整分析中,未同时使用阿片类药物和苯二氮卓类药物的几率比接受者比非接受者高 5%(1.05;95% 置信区间 = 1.02-1.09)。在阿片类药物过量使用的其他两项指标中,没有发现这些重大发现:结论:全面用药审查与减少医疗保险受益人同时使用阿片类药物和苯二氮卓类药物有关。此类服务应纳入当前应对阿片类药物流行的方法中。
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引用次数: 0
Measuring the knowledge and perception of Jordanian health science students towards self-prescribed medications: a descriptive analysis study 衡量约旦健康科学专业学生对自我处方药的认识和看法:一项描述性分析研究
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-11-29 DOI: 10.1093/jphsr/rmad049
R. M. Shudifat, Sultan Mosleh, Suhair Almakhzomi, Mohammad Al Shdifat, Malek Alnajar, Ja’far M Alkhawaldeh, L. Al-Halaseh
To assess the level of perception and awareness of health science students towards using over-the-counter (OTC) medicines and reveal any malpractice. A descriptive cross-sectional correlational study employing an internet-based self-administered questionnaire collected data from 342 participants. The study model comprised four compartments: introductory, socio-demographic, utilizing OTC medications, and estimating the perception level. Descriptive statistics were used to describe participants’ demographics and main study variables. Non-parametric descriptive analysis and chi-squared tests were used to determine significance across the three medical schools. The response rate among students in their first academic year (33.9%) was the highest. Most participants rely on OTC to treat minor conditions like pain and the common cold. Nutraceuticals have been used heavily. The participants showed a positive attitude towards self-treatment; the average perception score was 3.45 (SD = 0.60; 95%CI: 3.38–3.51). Besides, participants on regularly prescribed medications still determined the interaction between their treatments and non-prescribed medications. No significant association between attitude average score and participant age (r = −0.06; P = .273). Likewise, no differences were found in perceived attitude towards OTC based on gender (P = .41), academic level (P = .223), and college (P = .84). This study provides an overview of the level of medical student’s perception towards self-treatment; despite the promising levels of knowledge and perception, it is necessitated to introduce interprofessional medical education to get an integrated knowledge and qualified graduates to provide the best health services.
评估健康科学专业学生对使用非处方药(OTC)的看法和认识水平,并揭示任何不当行为。 这项描述性横断面相关研究采用了基于互联网的自填式问卷,收集了 342 名参与者的数据。研究模型由四个部分组成:入门、社会人口学、使用非处方药和感知水平估计。描述性统计用于描述参与者的人口统计学特征和主要研究变量。非参数描述性分析和卡方检验用于确定三所医学院的显著性。第一学年学生的回复率最高(33.9%)。 大多数参与者依靠非处方药来治疗疼痛和普通感冒等小病。营养保健品的使用率较高。参与者对自我治疗持积极态度,平均认知分数为 3.45(SD = 0.60;95%CI:3.38-3.51)。此外,定期服用处方药的参与者仍然认为他们的治疗与非处方药之间存在相互作用。态度平均得分与参与者年龄无明显关联(r = -0.06;P = .273)。同样,性别(P = .41)、学历(P = .223)和学院(P = .84)对非处方药的认知态度也没有差异。 本研究概述了医学生对自我治疗的认知水平;尽管医学生对自我治疗的认知和感知水平很高,但仍有必要引入跨专业医学教育,以获得综合知识和合格毕业生,从而提供最好的医疗服务。
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引用次数: 0
Community pharmacists’ perception and role in early diagnosis and health promotion of celiac disease 社区药剂师对乳糜泻早期诊断和健康宣传的看法和作用
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-11-29 DOI: 10.1093/jphsr/rmad048
Rawan Al-Suhaimat, L. Al-Halaseh, A. Al-Samydai
The study aims to measure pharmacists’ knowledge and perception of celiac disease. A Google form was used to collect data randomly from 283 pharmacists. The effects of each of the following hypotheses towards early diagnosis of celiac disease and patient compliance were studied: pharmacist’s experience in community pharmacies (H1), pharmacist’s knowledge (H2), pharmacist’s participation in continuing learning programmes (H3), and pharmacist’s attitude and practice (H4). A robust relationship between the variables was confirmed and was expressed by the moderate mean effect of H1, H2, H3, and H4 (2.3332, 2.3386, 2.1731, and 2.5717, respectively, and the correlation coefficient [r] of 0.797). Findings suggest that H1 is moderately correlated with H2 and H3 but weakly correlated with H4 (0.568 and 0.518, 0.183, respectively). Around a third of the participants (33.9%) admit their lack of knowledge regarding the symptoms. A third of the participants would refer the patients with recurrent symptoms to the physician. Three-quarters of the participants (78.4%) have not attended any educational programme, but they show a high desire (84.1%) to participate in such events either in person (50.2%) or through distance learning applications (36.4%). Pharmacists have crucial roles in early diagnosis, monitoring patient compliance, and providing counselling regarding celiac disease. Updating their knowledge should contribute to improving the overall health status of the patients and cutting off the expenses for the health sector.
本研究旨在测量药剂师对乳糜泻的了解和看法。 研究采用谷歌表格随机向 283 名药剂师收集数据。研究了以下假设对乳糜泻早期诊断和患者依从性的影响:药剂师在社区药房的工作经验(H1)、药剂师的知识(H2)、药剂师对继续学习计划的参与(H3)以及药剂师的态度和实践(H4)。 H1、H2、H3 和 H4 的中度平均效应(分别为 2.3332、2.3386、2.1731 和 2.5717,相关系数 [r] 为 0.797)证实了变量之间的稳健关系。研究结果表明,H1 与 H2 和 H3 呈中度相关,但与 H4 呈弱相关(分别为 0.568 和 0.518,0.183)。约有三分之一的参与者(33.9%)承认自己对症状缺乏了解。三分之一的参与者会将症状反复出现的患者转诊给医生。四分之三的参与者(78.4%)没有参加过任何教育课程,但他们(84.1%)非常希望亲自参加(50.2%)或通过远程学习应用参加(36.4%)此类活动。 药剂师在早期诊断、监测患者依从性和提供有关乳糜泻的咨询方面发挥着至关重要的作用。更新他们的知识应有助于改善患者的整体健康状况,并减少卫生部门的开支。
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引用次数: 0
Outcomes of pharmacy facility inspections: implications on pharmaceutical services 药房设施检查结果:对制药服务的影响
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-11-20 DOI: 10.1093/jphsr/rmad047
B. Singu, Priscilla Mutsambiwa, Ester Mvula
Good Pharmacy Practice (GPP) ensures access to quality medicines, a well-trained and adequate workforce of health professionals, and affordable healthcare. The Namibia Medicines Regulatory Council ensures the sale of medicines and the premises in which such sales are carried out comply with the Medicines and Related Substances Control Act of 2003. The purpose of this study was to report facility inspection outcomes. This was a retrospective review of inspection records archived over a period of 5 years (2017–2021) by the Namibia Medicines Regulatory Council. Compliance by facilities to 13 indicators as stipulated in the Namibia Medicines Regulatory Council inspections checklist adopted from international GPP guidelines was the main measure of outcomes. Results were summarized using descriptive statistics such as median, range, and percentages in R. The Mann–Whitney U test was used to compare medians. General compliance by community pharmacies (operated by pharmacists) was statistically higher (P = .0043) than dispensaries at clinics (mostly operated by nurses) with median (range) values of 84% (30.8–100) and 38% (0.0–100), respectively. There was an improvement in compliance over the 5 years for both pharmacies and clinics. The Ministry of Health & Social Services should implement policies that will ensure appropriately trained pharmaceutical cadres are stationed at all levels of the healthcare system to improve the delivery of pharmaceutical services. In addition, more inspectors need to be recruited for more frequent inspections.
良好药房做法(GPP)确保人们能够获得优质药品、训练有素和充足的保健专业人员队伍以及负担得起的保健服务。纳米比亚药品管理委员会确保药品销售和销售场所符合 2003 年《药品及相关物质管制法》。本研究的目的是报告设施检查结果。 这是对纳米比亚药品监管局 5 年(2017-2021 年)内存档的检查记录进行的回顾性审查。纳米比亚药品监管委员会检查清单中规定的 13 项指标(采用国际 GPP 准则)的合规情况是衡量成果的主要标准。采用描述性统计方法(如 R 中的中位数、范围和百分比)对结果进行总结,并使用 Mann-Whitney U 检验对中位数进行比较。 从统计学角度看,社区药房(由药剂师经营)的一般合规率(P = .0043)高于诊所药房(主要由护士经营),中位数(范围)分别为 84% (30.8-100) 和 38% (0.0-100)。5 年来,药房和诊所的达标率都有所提高。 卫生与社会服务部应实施相关政策,确保在各级医疗保健系统派驻经过适当培训的药剂干部,以改善药剂服务的提供。此外,还需要招聘更多的检查员,以进行更频繁的检查。
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引用次数: 0
Development and feasibility of an educational module on medication reconciliation for hospital pharmacists in the United Arab Emirates: a pilot study 阿拉伯联合酋长国医院药剂师药物和解教育模块的开发和可行性:一项试点研究
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-11-09 DOI: 10.1093/jphsr/rmad046
Alaa Farajallah, Hadzliana Zainal, Subish Palaian
Abstract Background The practice of medication reconciliation by pharmacists is minimal in United Arab Emirates hospitals. Objectives To design an educational module for pharmacists on medication reconciliation and assess its feasibility. Methods The study consisted of three parts: A pre-educational module survey using a validated knowledge, perception, practice, and barriers questionnaire (Cronbach’s α = 0.78), delivery of the educational module, and participants’ feedback. An educational module (general introduction to medication reconciliation, what is medication reconciliation, how to do medication reconciliation, and practicing medication reconciliation) was developed based on Miller’s pyramid and validated by three experts and pilot-tested. The knowledge and perceptions of pharmacists were evaluated by comparing pre-post educational module survey results. Results The module influenced the participants’ knowledge and perception of medication reconciliation. All of the participants gave ‘positive’ feedback on the intervention and the methodology applied, and they agreed on the need for training and workshops related to medication reconciliation. In addition, all ‘agreed’ that a lack of knowledge about medication reconciliation is the biggest barrier to medication reconciliation practices. The results further illustrated that all pharmacists had a ‘positive’ experience and ‘agreed strongly’ on understanding the majority of the content. Conclusion This study was successful in answering the research question by enrolling suitable participants, managing the timeline, and possessing resources for completing the study and hence considered feasible. This module can be utilized in continuous professional development programs to improve pharmacists’ knowledge, perceptions, and practice toward the medication reconciliation process aiming to reduce drug therapy-related problems in hospital settings.
背景在阿联酋的医院中,药剂师进行药物调解的实践很少。目的设计药师用药和解教育模块,并对其可行性进行评估。方法采用经验证的知识、感知、实践和障碍问卷(Cronbach ' s α = 0.78)进行学前教育模块调查,进行教育模块的发放,并听取参与者的反馈。以米勒金字塔理论为基础,开发了一个教育模块(药物和解概论、什么是药物和解、如何进行药物和解、实践药物和解),并经过三位专家的验证和试点测试。通过前后教育模块调查结果的比较,评价药师的知识和认知。结果该模块影响了被试对药物和解的认知和感知。所有的参与者都对干预措施和应用的方法给出了“积极”的反馈,他们同意需要进行与药物和解相关的培训和讲习班。此外,所有人都“同意”缺乏关于药物和解的知识是药物和解实践的最大障碍。结果进一步表明,所有药剂师都有一个“积极”的经验,并“强烈同意”理解大部分内容。本研究通过招募合适的参与者,管理时间线,拥有完成研究的资源,成功地回答了研究问题,因此认为是可行的。该模块可用于持续的专业发展计划,以提高药剂师的知识,观念和实践的药物调解过程,旨在减少在医院设置药物治疗相关问题。
{"title":"Development and feasibility of an educational module on medication reconciliation for hospital pharmacists in the United Arab Emirates: a pilot study","authors":"Alaa Farajallah, Hadzliana Zainal, Subish Palaian","doi":"10.1093/jphsr/rmad046","DOIUrl":"https://doi.org/10.1093/jphsr/rmad046","url":null,"abstract":"Abstract Background The practice of medication reconciliation by pharmacists is minimal in United Arab Emirates hospitals. Objectives To design an educational module for pharmacists on medication reconciliation and assess its feasibility. Methods The study consisted of three parts: A pre-educational module survey using a validated knowledge, perception, practice, and barriers questionnaire (Cronbach’s α = 0.78), delivery of the educational module, and participants’ feedback. An educational module (general introduction to medication reconciliation, what is medication reconciliation, how to do medication reconciliation, and practicing medication reconciliation) was developed based on Miller’s pyramid and validated by three experts and pilot-tested. The knowledge and perceptions of pharmacists were evaluated by comparing pre-post educational module survey results. Results The module influenced the participants’ knowledge and perception of medication reconciliation. All of the participants gave ‘positive’ feedback on the intervention and the methodology applied, and they agreed on the need for training and workshops related to medication reconciliation. In addition, all ‘agreed’ that a lack of knowledge about medication reconciliation is the biggest barrier to medication reconciliation practices. The results further illustrated that all pharmacists had a ‘positive’ experience and ‘agreed strongly’ on understanding the majority of the content. Conclusion This study was successful in answering the research question by enrolling suitable participants, managing the timeline, and possessing resources for completing the study and hence considered feasible. This module can be utilized in continuous professional development programs to improve pharmacists’ knowledge, perceptions, and practice toward the medication reconciliation process aiming to reduce drug therapy-related problems in hospital settings.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":" 37","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135291673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Time to treat the climate and nature crisis as one indivisible global health emergency 是时候将气候和自然危机视为一个不可分割的全球卫生紧急事件
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-10-25 DOI: 10.1093/jphsr/rmad045
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
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引用次数: 0
Trends in anti-neuropathic medications turnover in Iraq 伊拉克抗神经病药物周转趋势
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-10-25 DOI: 10.1093/jphsr/rmad042
Zainab M Al-Shammaa, Mohammed I Aladul, Narmin S Essa
Abstract Objectives Neuropathic pain (NP) is a type of chronic pain. Numerous diseases and/or lesions are associated with the development of NP, and diabetes mellitus is the most prevalent cause. Several classes of medications were recommended and/or approved as anti-neuropathic medications. This study aimed to examine the trends in the turnover of anti-neuropathic medications in Iraq. Methods This was a retrospective analysis of the turnover of selected anti-neuropathic medications in the Iraqi market derived from Advanced Marketing Statistics between 2017 and 2021. The sales units were converted to defined daily doses. Regression analysis and correlation analysis were used to compare the turnover of the medications. Key findings The overall volume of turnover of anti-neuropathic medications increased between 2017 and 2021. The anti-neuropathic market domination was shifted from carbamazepine to pregabalin, in which the average increase in pregabalin turnover of 60% [95% CI (confidence interval) 37.6–82.5] quarterly to achieve 42% of the market share (highest sales) by 2021. The overall expenditure on anti-neuropathic medications increased steadily over the study period. Conclusions The market of anti-neuropathic medications’ domination was shifted from the older antiepileptic drug (AED) (carbamazepine) to the newer AED (pregabalin). The availability and affordability of less expensive generic versions of these agents, together with the better safety profiles of the newer agents were the main driver for this shift. This indeed allowed Iraqi physicians to adhere to the latest international guidelines.
摘要目的神经性疼痛是一种慢性疼痛。许多疾病和/或病变与NP的发展有关,糖尿病是最常见的原因。有几类药物被推荐和/或批准为抗神经病变药物。本研究旨在研究伊拉克抗神经病变药物的周转趋势。方法回顾性分析2017年至2021年间伊拉克市场上选定的抗神经病变药物的营业额。销售单位被转换成规定的日剂量。采用回归分析和相关分析比较药品周转情况。2017年至2021年间,抗神经病变药物的总营业额有所增加。抗神经性疾病的市场主导地位从卡马西平转移到普瑞巴林,其中普瑞巴林的营业额平均每季度增长60% [95% CI(置信区间)37.6-82.5],到2021年达到42%的市场份额(最高销售额)。在研究期间,抗神经病变药物的总支出稳步增加。结论抗神经病变药物市场的主导地位由较老的抗癫痫药物(卡马西平)向较新的抗癫痫药物(普瑞巴林)转移。这些药物的廉价仿制药的可获得性和可负担性,以及新药物更好的安全性是这一转变的主要驱动因素。这确实使伊拉克医生能够遵守最新的国际准则。
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引用次数: 0
Awareness and beliefs of community pharmacists on disposal of unused and expired household medications in Indonesia: a cross-sectional study 印度尼西亚社区药剂师对处置未使用和过期家庭药物的认识和信念:一项横断面研究
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-10-19 DOI: 10.1093/jphsr/rmad043
Sofa D Alfian, Qisty A Khoiry, Mochammad A A Pratama, Wawan Wahyudin, Irma M Puspitasari, Ivan S Pradipta, Rizky Abdulah
Abstract Objective To assess the awareness and beliefs of community pharmacists regarding the disposal of expired and unused household medications in Indonesia. Methods A cross-sectional survey was conducted through convenience sampling. All pharmacists participating in a virtual training event were invited to take part in a self-administer voluntary online survey. A translated and validated questionnaire was used to assess awareness about the harm caused by improper disposal and the beliefs of the best location for collecting expired and unused household medications. Subsequently, demographic data such as age, gender, education level, and work experience of pharmacists were obtained through self-reported data. The characteristics of pharmacists and the outcomes were summarized using descriptive analysis. Correlation analysis was carried out to determine the association between sociodemographic variables and outcomes. Key findings A total of 202 pharmacists completed the survey (response rate: 96.2%). The majority were female (83.2%) and the mean work experience was 4.7 years. Approximately 86% of pharmacists were aware of the environmental harm caused by improper disposing of expired and unused household medications, and 98% acknowledged their role in preventing such risks. Approximately 70%–80% of the respondents believed that community pharmacies were the best location for the collection of expired and unused household medications. No significant associations were found among age, gender, education level, and years of experience and the outcomes. Conclusion Almost all pharmacists were aware of the risk of improper disposal of expired and unused household medications and acknowledged their responsibilities to protect the environment. The strong inclination of pharmacists to select pharmacies as collection points for expired and unused medications strongly advocates for the implementation of medication take-back programs in Indonesia.
【摘要】目的了解印尼社区药师对过期和未使用家庭用药处置的认知和信念。方法采用方便抽样的横断面调查方法。所有参加虚拟培训活动的药剂师都被邀请参加一项自我管理的自愿在线调查。使用了一份经过翻译和验证的问卷,以评估人们对不当处置造成的危害的认识,以及对收集过期和未使用的家庭药物的最佳地点的看法。随后,通过自述数据获得药师年龄、性别、受教育程度、工作经验等人口学数据。采用描述性分析方法总结药师的特点及结果。进行相关分析以确定社会人口学变量与结果之间的关联。共202名药师完成调查,回复率为96.2%。大多数是女性(83.2%),平均工作经验为4.7年。大约86%的药剂师意识到不当处理过期和未使用的家用药物会造成环境危害,98%的药剂师承认他们在预防此类风险方面的作用。大约70%-80%的受访者认为,社区药房是收集过期和未使用的家用药物的最佳地点。年龄、性别、受教育程度、工作年限与结果无显著相关性。结论几乎所有的药师都意识到过期和未使用的家庭用药处置不当的风险,并认识到保护环境的责任。药剂师强烈倾向于选择药店作为过期和未使用药物的收集点,这强烈支持在印度尼西亚实施药物回收计划。
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引用次数: 0
Patterns and factors associated with SSRI medication adherence: a retrospective study using pharmacy claims data 与SSRI药物依从性相关的模式和因素:一项使用药房索赔数据的回顾性研究
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-10-13 DOI: 10.1093/jphsr/rmad041
Bayan M Hijazi, Ioana Popovici, Mohammad B Nusair, Goar Alvarez
Abstract Objectives To assess the patterns and risk factors associated with selective serotonin reuptake inhibitor (SSRI) medication adherence among enrollees of a multiple employer welfare beneficiary association operating in Florida. Methods This study used a pharmacy claims database for beneficiaries of the Independent Colleges and Universities Benefits Association. The sample of 2541 patients were enrollees who filled two or more consecutive SSRI prescriptions during the analysis period 2015–20. Adherence was measured as the proportion of days covered by a medication. Multiple logistic regression analysis was used to explore the relationship between sociodemographic, healthcare access, and clinical and medication-related factors and adherence. Key findings Adherence was associated with higher odds of being female [odds ratio (OR): 1.2, 95% confidence interval (CI): 0.995–1.464, P &lt; .10] and higher pill burden (OR: 1.3, CI: 1.021–1.642, P&lt; 0.05). Patients using only retail pharmacies (OR: 0.356, CI: 0.196–0.645, P &lt; .01), having any out-of-pocket costs (OR: 0.552, CI: 0.348–0.875, P &lt; .50), changing the prescriber over the duration of the treatment (OR: 0.708, CI: 0.589–0.851, P &lt; .01), taking antihypertensive (OR: 0.708, CI: 0.5077–0.988, P &lt; 0.50), and asthma (OR: 0.609, CI: 0.450–0.826, P &lt; .01) medications were less likely to be adherent. Prescriber specialty was not found to be associated with adherence. Conclusion These findings can inform policymakers and healthcare insurance companies on barriers to medication access and recommend strategies to eliminate these barriers and design interventions to improve the adherence of groups at risk for nonadherence. Healthcare providers can identify patients who are less likely to be adherent and customize counseling interventions for these patients.
【摘要】目的评估佛罗里达州一家多雇主福利受益人协会参保人员选择性血清素再摄取抑制剂(SSRI)药物依从性的模式和危险因素。方法本研究使用独立学院和大学福利协会受益人的药房索赔数据库。2541例患者是在2015 - 2020年分析期间连续服用两次或两次以上SSRI处方的入组患者。依从性以服药天数的比例来衡量。采用多元logistic回归分析探讨社会人口学、医疗保健可及性、临床和药物相关因素与依从性之间的关系。依从性与女性的高几率相关[优势比(OR): 1.2, 95%可信区间(CI): 0.995-1.464, P <[10.10]和较高的药丸负担(OR: 1.3, CI: 1.021-1.642, p&p;0.05)。仅使用零售药店的患者(OR: 0.356, CI: 0.196-0.645, P <0.01),有任何自付费用(OR: 0.552, CI: 0.348-0.875, P <0.50),在治疗期间改变处方者(OR: 0.708, CI: 0.589-0.851, P <0.01),服用抗高血压药物(OR: 0.708, CI: 0.5077 ~ 0.988, P <0.50),哮喘(OR: 0.609, CI: 0.450-0.826, P <.01)药物的依从性较低。未发现处方医师专业与依从性相关。结论这些发现可以为政策制定者和医疗保险公司提供药物获取障碍的信息,并建议消除这些障碍的策略和设计干预措施,以提高有不依从风险群体的依从性。医疗保健提供者可以识别不太可能坚持的患者,并为这些患者定制咨询干预措施。
{"title":"Patterns and factors associated with SSRI medication adherence: a retrospective study using pharmacy claims data","authors":"Bayan M Hijazi, Ioana Popovici, Mohammad B Nusair, Goar Alvarez","doi":"10.1093/jphsr/rmad041","DOIUrl":"https://doi.org/10.1093/jphsr/rmad041","url":null,"abstract":"Abstract Objectives To assess the patterns and risk factors associated with selective serotonin reuptake inhibitor (SSRI) medication adherence among enrollees of a multiple employer welfare beneficiary association operating in Florida. Methods This study used a pharmacy claims database for beneficiaries of the Independent Colleges and Universities Benefits Association. The sample of 2541 patients were enrollees who filled two or more consecutive SSRI prescriptions during the analysis period 2015–20. Adherence was measured as the proportion of days covered by a medication. Multiple logistic regression analysis was used to explore the relationship between sociodemographic, healthcare access, and clinical and medication-related factors and adherence. Key findings Adherence was associated with higher odds of being female [odds ratio (OR): 1.2, 95% confidence interval (CI): 0.995–1.464, P &amp;lt; .10] and higher pill burden (OR: 1.3, CI: 1.021–1.642, P&amp;lt; 0.05). Patients using only retail pharmacies (OR: 0.356, CI: 0.196–0.645, P &amp;lt; .01), having any out-of-pocket costs (OR: 0.552, CI: 0.348–0.875, P &amp;lt; .50), changing the prescriber over the duration of the treatment (OR: 0.708, CI: 0.589–0.851, P &amp;lt; .01), taking antihypertensive (OR: 0.708, CI: 0.5077–0.988, P &amp;lt; 0.50), and asthma (OR: 0.609, CI: 0.450–0.826, P &amp;lt; .01) medications were less likely to be adherent. Prescriber specialty was not found to be associated with adherence. Conclusion These findings can inform policymakers and healthcare insurance companies on barriers to medication access and recommend strategies to eliminate these barriers and design interventions to improve the adherence of groups at risk for nonadherence. Healthcare providers can identify patients who are less likely to be adherent and customize counseling interventions for these patients.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135855353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Instruments to measure patient satisfaction with comprehensive medication management (CMM) services: a scoping review 测量患者对综合用药管理(CMM)服务满意度的工具:范围审查
Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-10-10 DOI: 10.1093/jphsr/rmad044
Lorayne Caroline Resende, Mariana Michel Barbosa, Cristiane de Paula Rezende, Laís Lessa Neiva Pantuza, Edna Afonso Reis, Mariana Martins Gonzaga Nascimento
Abstract Objectives To map the instruments to measure patient satisfaction with comprehensive medication management (CMM) services and to compare them according to their development characteristics and applicability of patient-reported outcome measures (PRO) measures. Methods A scoping review was conducted using the methodology proposed by the Joanna Briggs Institute and the PRISMA Extension for Scoping Reviews (PRISMA-ScR). Studies that developed or applied a patient satisfaction measurement instrument in CMM services, published from 1990 onwards were selected. The critical appraisal of the instruments identified was carried out using an 18 item checklist developed to systematically evaluate PRO measures. Key findings A total of 28 studies were selected; in most (17), the applied instruments had been developed by the authors. Nine of them were validated, most of which used open-ended and closed questions in self-administered printed instruments. The best-qualified instrument reached 11 out of the 18 evaluated items, highlighting the difficulty in the definition of the satisfaction construct. Conclusions The review made it possible to identify the instruments available to measure patient satisfaction with CMM services and to comparatively highlight their characteristics and psychometric properties. It also pointed out the need to improve or develop a patient satisfaction instrument for CMM services. However, improvement is needed in many of the evaluated domains of the instruments to meet the desirable requirements for a PRO measure. These gaps should be taken into consideration in future research, aiming to build a robust and standardized instrument for the CMM service.
【摘要】目的绘制综合用药管理(CMM)服务满意度测评工具图谱,比较其发展特点和患者报告结果测量(PRO)指标的适用性。方法采用乔安娜布里格斯研究所和PRISMA范围审查扩展(PRISMA- scr)提出的方法进行范围审查。研究开发或应用的病人满意度测量工具在CMM服务,从1990年以来发表的选择。对所确定的仪器进行了批判性评估,使用了一份18项清单来系统地评估PRO措施。本研究共纳入28项研究;在大多数(17)中,应用的仪器是由作者开发的。其中9项已得到验证,其中大多数在自行管理的印刷文书中使用开放式和封闭式问题。在18个评估项目中,最合格的工具达到了11个,突出了满意度结构定义的难度。结论本综述确定了可用的测量CMM服务患者满意度的工具,并比较突出了它们的特点和心理测量学性质。报告还指出,有必要改进或开发一种患者满意度测量工具。然而,仪器的许多评估领域需要改进,以满足PRO测量的理想要求。这些差距应该在未来的研究中加以考虑,旨在为CMM服务建立一个健壮和标准化的仪器。
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Journal of Pharmaceutical Health Services Research
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