模拟生物环境中的光子迁移过程

V. Pavlov, J. R. Rovira, N. Zabolotna, V. V. Kholin, L. Nykyforova, O. Komarova
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引用次数: 0

摘要

在对表皮样本各向异性参数的二维分布进行分析后得出的文章中,只发现了线性双折射,其值会根据组织纤维的厚度和密度在切片平面上发生变化。相应地,沿着相同的纤维方向,双折射轴的方向也会发生平滑变化(在没有病变的组织区域)。对于受影响的组织区域,横截面上的双折射值更加均匀,而在可见严重损伤的区域,双折射值则很小。在病变较小且清晰可见的区域,双折射的方向变化是混乱的。因此,黑色素瘤会严重破坏表皮细胞,使其变得几乎各向同性。健康的组织样本具有自然的方向顺序。
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Simulation of photon migration process in the biological environment
In the article developed as a result of the analysis of the obtained 2D distributions of the anisotropy parameters of the epidermis samples, only linear birefringence was found, the value of which changes in the plane of the section according to the thickness and density of the tissue fibers. Correspondingly, along the same fiber directions, the orientation of the birefringence axis changes smoothly (in the area of ​​the tissue without pathology). For the affected areas of the tissue, the birefringence value is more homogeneous in the cross-section, and in the areas with visible severe damage it is minimal. The change in the orientation of in areas with a small and clearly visible lesion is chaotic. Thus, melanoma destroys epidermal cells so much that they become practically isotropic. Healthy tissue samples have a natural orientational order.
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