SK Umeraazmi, B. Krishna Reddy, K. Raja Sekhar Reddy, R. Ramesh, S. Jayasree, S. Sandeep, B. Thangabalan
{"title":"用紫外法测定合成果冻并验证雷米普利","authors":"SK Umeraazmi, B. Krishna Reddy, K. Raja Sekhar Reddy, R. Ramesh, S. Jayasree, S. Sandeep, B. Thangabalan","doi":"10.18231/j.ijpca.2024.024","DOIUrl":null,"url":null,"abstract":"Chalcone is an α,β- unsaturated ketone and central core for a variety of important biological compounds extracted from natural products and the experiment is conducted by performing identification tests to identify the chemical components in the compounds such as and are the main components used in this procedure. The synthesized jelly is developed and validated by ramipril and its linearity is found to be 10-50 µg/ml, precision % RSD of in intraday 35.7142 and in inter day 35.7277, Accuracy and recovery studies 80 %, 100%,120% are found to be 82,95,103,. Specificity % RSD is 29.43, Robustness wavelengths are taken as 210 nm, 211nm,212 nm found to be 3.345,26.182,21.038, LOD – 0.8µg/ml, LOQ - 2.5 µg/ml. The amount present in chalcone jelly in given sample of ramipril was 81µg/ml.","PeriodicalId":14182,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":" 17","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Determination of the synthesised jelly by UV method development and validation of ramipril\",\"authors\":\"SK Umeraazmi, B. Krishna Reddy, K. Raja Sekhar Reddy, R. Ramesh, S. Jayasree, S. Sandeep, B. Thangabalan\",\"doi\":\"10.18231/j.ijpca.2024.024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chalcone is an α,β- unsaturated ketone and central core for a variety of important biological compounds extracted from natural products and the experiment is conducted by performing identification tests to identify the chemical components in the compounds such as and are the main components used in this procedure. The synthesized jelly is developed and validated by ramipril and its linearity is found to be 10-50 µg/ml, precision % RSD of in intraday 35.7142 and in inter day 35.7277, Accuracy and recovery studies 80 %, 100%,120% are found to be 82,95,103,. Specificity % RSD is 29.43, Robustness wavelengths are taken as 210 nm, 211nm,212 nm found to be 3.345,26.182,21.038, LOD – 0.8µg/ml, LOQ - 2.5 µg/ml. The amount present in chalcone jelly in given sample of ramipril was 81µg/ml.\",\"PeriodicalId\":14182,\"journal\":{\"name\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"volume\":\" 17\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmaceutical Chemistry and Analysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijpca.2024.024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry and Analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijpca.2024.024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Determination of the synthesised jelly by UV method development and validation of ramipril
Chalcone is an α,β- unsaturated ketone and central core for a variety of important biological compounds extracted from natural products and the experiment is conducted by performing identification tests to identify the chemical components in the compounds such as and are the main components used in this procedure. The synthesized jelly is developed and validated by ramipril and its linearity is found to be 10-50 µg/ml, precision % RSD of in intraday 35.7142 and in inter day 35.7277, Accuracy and recovery studies 80 %, 100%,120% are found to be 82,95,103,. Specificity % RSD is 29.43, Robustness wavelengths are taken as 210 nm, 211nm,212 nm found to be 3.345,26.182,21.038, LOD – 0.8µg/ml, LOQ - 2.5 µg/ml. The amount present in chalcone jelly in given sample of ramipril was 81µg/ml.