透皮丁丙诺啡贴片与透皮双氯芬酸贴片用于脐下择期手术术后镇痛的比较研究

Farha Deeba Rajasab, Sherley S. Cherian, Rakesh Kalappa, Haripriya Ramachandran
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引用次数: 0

摘要

目的:有效的术后疼痛管理对患者的康复和满意度至关重要。本研究比较了经皮丁丙诺啡(一种阿片类镇痛药)和双氯芬酸(一种非甾体抗炎药)在择期脐下手术中缓解术后疼痛的有效性和安全性。方法:100 名接受择期脐下手术的患者被随机分为两组,分别接受经皮丁丙诺啡贴片或双氯芬酸贴片。分别在基线、贴敷后1周、2周和4周测量使用数字评分量表(NRS)的疼痛评分、使用WOMAC指数评估的功能恢复情况以及患者满意度:结果:随着时间的推移,两组患者的疼痛均有明显减轻。结果:随着时间的推移,两组患者的疼痛均有明显减轻,但在用药后 1 W 和 2 W,双氯芬酸组的疼痛缓解程度更大(p<0.001),患者满意度更高。使用 4 W 后,两组的疼痛评分和 WOMAC 指数差异无统计学意义,这表明两组的长期疗效相似:结论:虽然透皮丁丙诺啡和双氯芬酸贴片都能有效控制术后疼痛,但双氯芬酸贴片的短期缓解效果和患者满意度更好。根据患者的不同需求和恢复阶段调整疼痛治疗策略对于优化术后护理至关重要。
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A COMPARATIVE STUDY OF TRANSDERMAL BUPRENORPHINE PATCH VERSUS TRANSDERMAL DICLOFENAC PATCH FOR POST-OPERATIVE ANALGESIA IN ELECTIVE BELOW UMBILICAL SURGERIES
Objective: Effective postoperative pain management is crucial for recovery and patient satisfaction. This study compares the efficacy and safety of transdermal buprenorphine, an opioid analgesic, with diclofenac, a non-steroidal anti-inflammatory drug (NSAID), for postoperative pain relief in elective below umbilical surgeries. Methods: Hundred patients undergoing elective below-umbilical surgeries were randomized into two groups to receive either a transdermal buprenorphine patch or a diclofenac patch. Pain scores using the Numeric Rating Scale (NRS), functional recovery assessed by the WOMAC Index, and patient satisfaction were measured at baseline, 1 w, 2 w, and 4 w post-application. Results: Both groups showed significant pain reduction over time. However, at 1 and 2 W post-application, the diclofenac group exhibited greater pain relief (p<0.001) and higher patient satisfaction. By the 4 w, differences in pain scores and WOMAC Index between the groups were not statistically significant, indicating similar long-term efficacy. Conclusion: While both transdermal buprenorphine and diclofenac patches are effective for postoperative pain management, diclofenac patches offer superior short-term relief and patient satisfaction. Tailoring pain management strategies to individual patient needs and recovery phases is essential for optimizing postoperative care.
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