加拿大魁北克省 10-24 岁青少年因滥用镇静剂住院的变化模式

Nathalie Auger , Jessica Healy-Profitós , Gabriel Côté-Corriveau
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引用次数: 0

摘要

目的评估青少年滥用镇静剂住院治疗的趋势。方法我们采用序列横断面设计,计算了加拿大魁北克省 5-24 岁人群中与镇静剂相关的自杀未遂、镇静剂使用障碍和其他镇静剂中毒的住院率。我们计算了 2006-2011 年、2012-2017 年和 2018-2023 年与镇静剂相关的住院率,并使用比率比 (RR) 和 95 % 置信区间 (CI) 比较了最后一个时间段与第一个时间段之间的差异,研究了不同年龄、性别、多种药物使用、精神健康合并症和社会脆弱性的差异。使用镇静剂自杀未遂的比例从2006-2011年的每10万名青少年50.5例增加到2012-2017年的82.2例和2018-2023年的114.4例(RR为2.26,95 % CI为1.63-3.15),而在同一时期,镇静剂使用障碍的比例从每10万名青少年13.1例增加到21.8例和60.5例(RR为4.62,95 % CI为2.54-8.40)。在 10-24 岁的青少年中,男女发病率都有所上升,尤其是在使用多种药物、患有焦虑症和注意力障碍以及社会脆弱性的青少年中。讨论需要住院治疗的镇静剂滥用似乎是青少年中一个日益严重的问题。
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Changing patterns of hospitalization for sedative misuse among youth aged 10–24 years in Quebec, Canada

Purpose

To assess trends in hospitalization for sedative misuse among youth.

Methods

Using a serial cross-sectional design, we computed hospitalization rates for sedative-related suicide attempts, sedative use disorders, and other sedative poisonings within individuals aged 5–24 years in Quebec, Canada. We computed sedative-related hospitalization rates in 2006–2011, 2012–2017, and 2018–2023, and examined differences according to age, sex, polysubstance use, mental health comorbidity, and social vulnerability using rate ratios (RR) and 95 % confidence intervals (CI) comparing the last time period relative to the first.

Results

Sedative-related hospitalization rates more than doubled during the study. Suicide attempts using sedatives increased from 50.5 per 100,000 youth in 2006–2011, to 82.2 in 2012–2017 and 114.4 in 2018–2023 (RR 2.26, 95 % CI 1.63–3.15), while sedative use disorders increased from 13.1 to 21.8 and 60.5 per 100,000 in these same time periods (RR 4.62, 95 % CI 2.54–8.40). Rates increased for 10–24 year-olds and in both sexes, particularly among youth with polysubstance use, anxiety and attention disorders, and social vulnerability.

Discussion

Sedative misuse requiring hospitalization appears to be a growing issue among youth.

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来源期刊
Drug and alcohol dependence reports
Drug and alcohol dependence reports Psychiatry and Mental Health
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审稿时长
100 days
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