Piceatannol, a comprehensive review of health perspectives and pharmacological aspects

Piceatannol, a natural polyphenolic stilbenoid found in numerous fruits and vegetables such as grapes, passionate fruit, blueberries, and white tea, is well recognized for its diverse pharmacological effects. Numerous previous research studies demonstrated the intriguing bioactivity of piceatannol, including its antioxidant, anti-inflammatory, and cancer preventive and neuroprotective properties. It has also shown potential benefits in managing hypercholesterolemia, atherosclerosis, angiogenesis, and cardiovascular diseases. Accordingly, this comprehensive review aims to provide an updated overview and covers the recent literature dealing with the chemistry of piceatannol, its bioavailability, pharmacological activities, and potential health benefits. In addition, the review will focus on the medicinal and traditional significance of piceatannol in combating various diseases and ailments.