用于化妆品和护肤品的微藻小球藻 LCMS 和傅立叶变换红外光谱分析

Yamuna Ganeson , Primilla Paramasivam , Karthick Murugan Palanisamy , Natanamurugaraj Govindan , Gaanty Pragas Maniam
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引用次数: 0

摘要

阳光中的紫外线辐射量极高,会对皮肤造成伤害。应该采取预防措施,比如涂抹一层能够保护皮肤免受紫外线伤害的保护层。因此,保护层应含有抗氧化成分,能够防止自由基的形成。微藻和从微藻中提取的生物活性成分被认为是化妆品和制药业中可行的原材料替代品。本研究利用 LC-QTOF 成功鉴定了小球藻中具有抗氧化特性的类胡萝卜素化合物,如新黄素和隐黄素。同时,通过 LC-QTOF 成功鉴定了小球藻中的酚类化合物,据报道这也是防晒产品中的一种活性化合物。此外,还通过傅立叶变换红外光谱分析对多糖化合物进行了鉴定,并成功确定了其中存在的官能团。据报道,多糖具有很好的抗皱特性。海藻酸化合物是根据所形成的峰值来确定官能团的。海藻酸化合物具有很好的清除自由基的作用。因此,小球藻可用于化妆品和护肤品,因为其抗氧化化合物(如酚类化合物、类胡萝卜素和多糖)已被鉴定出来。
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LCMS and FTIR profiling of microalga Chlorella sp. for cosmetics and skin care applications

People are exposed to extreme levels of UV radiation from the sun which gives a harmful effect on the skin. A prevention step should be taken such as applying a protective layer that able to protect the skin from UV rays. Hence, the protective layer should contain the antioxidant components that are able to prevent the formation of free radicals. Microalgae and the bioactive components that can be derived from them are thought to be viable raw material replacements in the cosmetics and pharmaceutical industries. In this study, carotenoid compounds with antioxidant characteristics such as neoxanthin and cryptoxanthin were successfully identified in Chlorella sp. by LC‑QTOF and the compounds have been reported to give a shield from skin aging. Meanwhile, the phenolic compounds were successfully identified through LC‑QTOF in Chlorella sp. that also been reported to be an active compound in sunscreen products. Besides, the identification of polysaccharide compounds was done by FTIR analysis, and the presence of the functional group was successfully identified. Polysaccharides have been reported to be an excellent anti-wrinkles characteristic. The alginate compound was analyses from the identification of a functional group based on the peaks formed. The alginate compound has been an excellent free radical scavenging. Therefore, Chlorella sp. can be applicable for cosmetics and skincare products as the antioxidant compounds such as phenolics compound, carotenoids, and polysaccharides have been identified.

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