作为高灵敏度无标记生物传感器的 P+ 袋掺杂 4H-SiC 肖特基势垒场效应晶体管

IF 2.7 Q2 PHYSICS, CONDENSED MATTER Micro and Nanostructures Pub Date : 2024-07-19 DOI:10.1016/j.micrna.2024.207931
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摘要

本文提出了一种基于介电调制效应、带有 P+ 掺杂袋的 4H-SiC 肖特基势垒场效应晶体管,用于无标记生物分子检测。通过优化 P+掺杂袋的长度和位置,当 P+掺杂袋位于距离肖特基触点 1 nm、长度为 5 nm 的沟道内时,生物传感器的灵敏度达到最大。我们利用 Sentaurus TCAD 对不同介电常数和不同电荷密度的生物分子进行了模拟。结果表明,对于 K = 12 的中性生物分子,新结构的导通电流灵敏度为 1.03 × 108,最大跨导灵敏度为 6.24 × 107,阈值电压灵敏度为 65 mV,离子/关断比灵敏度为 1.8 × 104。此外,本文还考虑了空腔的填充因子和拟议结构的线性度。此外,本文还将拟议结构的导通电流灵敏度与现有技术进行了比较,结果表明我们提出的生物传感器具有很高的灵敏度。本文提出的生物传感器具有体积小、灵敏度高的特点,因此被广泛应用于要求高集成度和高效检测的生物医学检测领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A P+ pocket doped 4H–SiC Schottky barrier FET as highly sensitive label-free biosensor

In this paper, a 4H–SiC Schottky barrier field-effect transistor with a P+ doping Pocket based on dielectric modulation effect for label-free detection of biomolecules has been proposed. Upon optimization of the length and position of P+ doping pocket, the sensitivity of the biosensor achieves the maximum when it is located within the channel 1 nm away from the Schottky contact with a length of 5 nm. Simulations have been performed for different dielectric constants and biomolecules with different charge densities by Sentaurus TCAD. The results show that the new structure has an on-current sensitivity of 1.03 × 108, a maximum transconductance sensitivity of 6.24 × 107, a threshold voltage sensitivity of 65 mV, and an Ion/Ioff ratio sensitivity of 1.8 × 104 for neutral biomolecules with K = 12. In addition, the fill factor of the cavity and linearity of the proposed structure are considered in this paper. Further, the on-current sensitivity of our proposed structure is gauged against state of the art, which demonstrate a high sensitivity of our proposed biosensors. The smaller size and prominent sensitivity characteristics of the biosensor proposed in this paper have made it widely used in the field of biomedical detection that requires high integration and efficient detection.

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