Aqsa Kamal , Maryam Kamal , Alina Hasnat , Abeera Mohsin , A.R. Samsudin
{"title":"拔牙创口的愈合，我们目前了解多少？","authors":"Aqsa Kamal , Maryam Kamal , Alina Hasnat , Abeera Mohsin , A.R. Samsudin","doi":"10.1016/j.ajoms.2024.07.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This review paper aims to provide an up to date understanding on tooth socket healing signifying the impact of osteoimmunology, cellular and molecular events, role of nerves, growth factors, signaling pathways, oxygen, endocrine and obesity in healing and regeneration.</div></div><div><h3><strong>Methods</strong></h3><div>A thorough literature search was conducted using up to date software and electronic databases including Python 3.9.7 and latent Dirichlet allocation (LDA).</div></div><div><h3><strong>Results</strong></h3><div>70 relevant articles were included. Tooth socket healing is different from other types of bone healing.</div></div><div><h3><strong>Conclusion</strong></h3><div>Role of osteoimmunology, macrophages, mesenchymal stem cells, growth factors, hormones and nerves in tooth socket healing have been ignored for long. These factors can result in impaired wound healing or disruption the healing process. Understanding the mechanisms involved in tooth socket healing can contribute to the development of targeted strategies for promoting optimal healing outcomes.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 8-22"},"PeriodicalIF":0.4000,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Healing of tooth extraction wound socket, do we have current understanding?\",\"authors\":\"Aqsa Kamal , Maryam Kamal , Alina Hasnat , Abeera Mohsin , A.R. Samsudin\",\"doi\":\"10.1016/j.ajoms.2024.07.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>This review paper aims to provide an up to date understanding on tooth socket healing signifying the impact of osteoimmunology, cellular and molecular events, role of nerves, growth factors, signaling pathways, oxygen, endocrine and obesity in healing and regeneration.</div></div><div><h3><strong>Methods</strong></h3><div>A thorough literature search was conducted using up to date software and electronic databases including Python 3.9.7 and latent Dirichlet allocation (LDA).</div></div><div><h3><strong>Results</strong></h3><div>70 relevant articles were included. Tooth socket healing is different from other types of bone healing.</div></div><div><h3><strong>Conclusion</strong></h3><div>Role of osteoimmunology, macrophages, mesenchymal stem cells, growth factors, hormones and nerves in tooth socket healing have been ignored for long. These factors can result in impaired wound healing or disruption the healing process. Understanding the mechanisms involved in tooth socket healing can contribute to the development of targeted strategies for promoting optimal healing outcomes.</div></div>\",\"PeriodicalId\":45034,\"journal\":{\"name\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"volume\":\"37 1\",\"pages\":\"Pages 8-22\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212555824001248\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212555824001248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Healing of tooth extraction wound socket, do we have current understanding?
Objective
This review paper aims to provide an up to date understanding on tooth socket healing signifying the impact of osteoimmunology, cellular and molecular events, role of nerves, growth factors, signaling pathways, oxygen, endocrine and obesity in healing and regeneration.
Methods
A thorough literature search was conducted using up to date software and electronic databases including Python 3.9.7 and latent Dirichlet allocation (LDA).
Results
70 relevant articles were included. Tooth socket healing is different from other types of bone healing.
Conclusion
Role of osteoimmunology, macrophages, mesenchymal stem cells, growth factors, hormones and nerves in tooth socket healing have been ignored for long. These factors can result in impaired wound healing or disruption the healing process. Understanding the mechanisms involved in tooth socket healing can contribute to the development of targeted strategies for promoting optimal healing outcomes.
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