健康认知老龄化的生活方式医学:叙述性综述

Matthew Halma , Paul Marik , Suzanne Gazda , Jack Tuszynski
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摘要

全球许多国家都在经历人口老龄化,这使人们对这些人口的体质和能力产生了怀疑。全球神经退行性疾病的发病率正在上升,即使在对寿命延长进行调整后也是如此。这一令人担忧的趋势促使人们采取措施预防痴呆症。本综述总结了以生活方式医学为基础,采用多种方式和干预措施预防痴呆症和认知能力下降的工作。我们的研究结果为那些希望通过饮食、运动和正念等干预措施保持晚年认知健康的人们带来了希望。利用廉价且可扩展的干预措施是缓解神经退行性疾病预期趋势的重要策略。本综述涵盖了可减轻阿尔茨海默病负担的潜在生活方式和饮食干预措施,为神经退行性疾病的人群预防方法铺平了道路。
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Lifestyle medicine for healthy cognitive aging: A narrative review

Many countries across the globe are experiencing aging populations, which brings into question the fitness and capacity of these populations. Rates of neurodegenerative diseases worldwide are increasing, even after adjusting for increasing lifespans. This worrying trend motivates taking steps in the population to prevent dementia. This review summarizes the work on lifestyle medicine based prevention of dementia and cognitive decline using multiple modalities and interventions. Our results bring hope to those seeking to stay cognitively healthy in advanced age through combinations of diet, exercise, and mindfulness based interventions. Leveraging cheap and scalable interventions is an important strategy for alleviating the expected tide of neurodegenerative illnesses. This review covers the potential lifestyle and dietary interventions which can alleviate Alzheimer’s disease burden, paving the way for population level preventative approaches for neurodegenerative disease.

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