{"title":"铅暴露对呼吸系统健康的影响：系统回顾与荟萃分析","authors":"Tao Chen, Kexin Dai, Huihui Wu","doi":"10.1007/s11869-024-01619-x","DOIUrl":null,"url":null,"abstract":"<div><p>In recent years, the incidence of respiratory diseases such as asthma and pneumonia has increased significantly. However, the effect of lead (Pb) pollution on the respiratory system remains unclear. The aim of this study was to evaluate the effects of exposure to environmental and occupational Pb on respiratory health. Articles published in PubMed and Web of Science before September 2023 were systematically searched. The overall adjusted odds ratio (OR) and 95% confidence intervals (CIs) for the association between Pb exposure and respiratory diseases were extracted from each relevant article. The random effects model was applied to analyze the overall pooled effect estimates. Among the 36,373 search results, 36 related articles were screened for meta-analysis. The results of the meta-analysis suggested that Pb exposure increased the risk of respiratory diseases: OR = 1.12 (95% CIs: 1.05, 1.18). The funnel plot, Egger’s and Begg’s tests showed no publication bias. Sensitivity analysis confirmed that the meta-analysis was statistically reliable and stable. Environmental and occupational Pb exposure is associated with an increased risk of respiratory diseases including asthma. The study highlights the importance of further research on the harmful effects of Pb and the urgency of mitigating air pollution.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":49109,"journal":{"name":"Air Quality Atmosphere and Health","volume":"17 12","pages":"3031 - 3044"},"PeriodicalIF":2.9000,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of lead exposure on respiratory health: a systematic review and meta-analysis\",\"authors\":\"Tao Chen, Kexin Dai, Huihui Wu\",\"doi\":\"10.1007/s11869-024-01619-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In recent years, the incidence of respiratory diseases such as asthma and pneumonia has increased significantly. However, the effect of lead (Pb) pollution on the respiratory system remains unclear. The aim of this study was to evaluate the effects of exposure to environmental and occupational Pb on respiratory health. Articles published in PubMed and Web of Science before September 2023 were systematically searched. The overall adjusted odds ratio (OR) and 95% confidence intervals (CIs) for the association between Pb exposure and respiratory diseases were extracted from each relevant article. The random effects model was applied to analyze the overall pooled effect estimates. Among the 36,373 search results, 36 related articles were screened for meta-analysis. The results of the meta-analysis suggested that Pb exposure increased the risk of respiratory diseases: OR = 1.12 (95% CIs: 1.05, 1.18). The funnel plot, Egger’s and Begg’s tests showed no publication bias. Sensitivity analysis confirmed that the meta-analysis was statistically reliable and stable. Environmental and occupational Pb exposure is associated with an increased risk of respiratory diseases including asthma. The study highlights the importance of further research on the harmful effects of Pb and the urgency of mitigating air pollution.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":49109,\"journal\":{\"name\":\"Air Quality Atmosphere and Health\",\"volume\":\"17 12\",\"pages\":\"3031 - 3044\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Air Quality Atmosphere and Health\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11869-024-01619-x\",\"RegionNum\":4,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Air Quality Atmosphere and Health","FirstCategoryId":"93","ListUrlMain":"https://link.springer.com/article/10.1007/s11869-024-01619-x","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
Effect of lead exposure on respiratory health: a systematic review and meta-analysis
In recent years, the incidence of respiratory diseases such as asthma and pneumonia has increased significantly. However, the effect of lead (Pb) pollution on the respiratory system remains unclear. The aim of this study was to evaluate the effects of exposure to environmental and occupational Pb on respiratory health. Articles published in PubMed and Web of Science before September 2023 were systematically searched. The overall adjusted odds ratio (OR) and 95% confidence intervals (CIs) for the association between Pb exposure and respiratory diseases were extracted from each relevant article. The random effects model was applied to analyze the overall pooled effect estimates. Among the 36,373 search results, 36 related articles were screened for meta-analysis. The results of the meta-analysis suggested that Pb exposure increased the risk of respiratory diseases: OR = 1.12 (95% CIs: 1.05, 1.18). The funnel plot, Egger’s and Begg’s tests showed no publication bias. Sensitivity analysis confirmed that the meta-analysis was statistically reliable and stable. Environmental and occupational Pb exposure is associated with an increased risk of respiratory diseases including asthma. The study highlights the importance of further research on the harmful effects of Pb and the urgency of mitigating air pollution.
期刊介绍：
Air Quality, Atmosphere, and Health is a multidisciplinary journal which, by its very name, illustrates the broad range of work it publishes and which focuses on atmospheric consequences of human activities and their implications for human and ecological health.
It offers research papers, critical literature reviews and commentaries, as well as special issues devoted to topical subjects or themes.
International in scope, the journal presents papers that inform and stimulate a global readership, as the topic addressed are global in their import. Consequently, we do not encourage submission of papers involving local data that relate to local problems. Unless they demonstrate wide applicability, these are better submitted to national or regional journals.
Air Quality, Atmosphere & Health addresses such topics as acid precipitation; airborne particulate matter; air quality monitoring and management; exposure assessment; risk assessment; indoor air quality; atmospheric chemistry; atmospheric modeling and prediction; air pollution climatology; climate change and air quality; air pollution measurement; atmospheric impact assessment; forest-fire emissions; atmospheric science; greenhouse gases; health and ecological effects; clean air technology; regional and global change and satellite measurements.
This journal benefits a diverse audience of researchers, public health officials and policy makers addressing problems that call for solutions based in evidence from atmospheric and exposure assessment scientists, epidemiologists, and risk assessors. Publication in the journal affords the opportunity to reach beyond defined disciplinary niches to this broader readership.
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