幽门螺杆菌:针对老对手的最新疗法简评。

IF 3.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Cleveland Clinic Journal of Medicine Pub Date : 2024-08-01 DOI:10.3949/ccjm.91a.24031
Wafa A Aldhaleei, Michael B Wallace, Dana M Harris, Yan Bi
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引用次数: 0

摘要

幽门螺杆菌是一个重大的公共卫生问题,因为它的发病率高、抗生素耐药性和致癌作用不断增加,所有这些都给内科医生、消化科医生和其他专科医生的管理带来了挑战。全球近一半的人口都携带幽门螺杆菌,其致癌后遗症是许多从业人员关注的问题。最新指南建议使用非侵入性或侵入性方法对幽门螺杆菌高危人群进行检测。根除幽门螺杆菌的治疗方案是根据是否存在有效的经验疗法(特定治疗方案的局部治愈率≥90%)或抗菌药物敏感性检测来定制的。当经验疗法治愈率不理想时,指南建议进行抗菌药物药敏试验,以提高根除率,减少抗生素耐药性的产生。
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Helicobacter pylori: A concise review of the latest treatments against an old foe.

Helicobacter pylori is a significant public health concern given its high prevalence, growing rates of antibiotic resistance, and carcinogenic effect, all of which create management challenges for internists, gastroenterologists, and other specialty physicians. With almost half of the world's human population harboring H pylori, carcinogenic sequelae are a concern to many practitioners. Recent guidelines recommend testing high-risk populations for H pylori using noninvasive or invasive methods. H pylori eradication regimens are tailored based on the presence of effective empiric therapy (local cure rates ≥ 90% for a given regimen) or antimicrobial susceptibility testing. When empiric therapy cure rates are not optimal, guidelines recommend antimicrobial susceptibility testing to improve eradication rates and reduce the progression of antibiotic resistance.

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来源期刊
Cleveland Clinic Journal of Medicine
Cleveland Clinic Journal of Medicine 医学-医学:内科
CiteScore
3.80
自引率
0.00%
发文量
109
审稿时长
6-12 weeks
期刊介绍: The mission of Cleveland Clinic Journal of Medicine (CCJM) is to provide its readers with up-to-date, practical, clinical information relevant to internal medicine, cardiology, and related fields. Consistent with this mission, CCJM focuses on timely review articles and other content that has a continuing-education orientation rather than on original research or case reports. CCJM authors, drawn from Cleveland Clinic and other top medical institutions throughout the world, are asked to identify new findings that are changing the practice of medicine and to advise readers how to apply them in daily patient care. Authors are chosen for their experience, acquired through caring for patients, teaching other physicians, and researching clinical questions.
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