个体和生化水平的生物标志物:纯溴氰菊酯和配制溴氰菊酯对 Boana pulchella 蝌蚪(Duméril 和 Bibron,1841 年)的影响。

IF 3.6 4区 环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES Environmental Toxicology and Chemistry Pub Date : 2024-08-02 DOI:10.1002/etc.5961
Evelina Barreto, Jorgelina Villanova, Carolina Parra, Manuel Flores, Carolina Salgado Costa, Cecilia Lascano, Guillermo Natale, Andrés Venturino
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引用次数: 0

摘要

我们比较了纯活性成分高效氯氟氰菊酯和配制产品(Zero®)对自生物种 Boana pulchella 幼虫期的影响。我们评估了生态毒理学终点、行为和发育改变,以及生化解毒、神经毒性和氧化应激反应,涵盖了从环境浓度到高施用水平的广泛浓度范围。两种拟除虫菊酯制剂显示出相似的生态毒性(中位数致死浓度约为 0.5 毫克/升),Zero® 的致死效应比活性成分的致死效应更明显。在浓度低1000倍的情况下,蝌蚪的产卵活动会发生亚致死行为改变,这表明在环境相关浓度下,蝌蚪接触这种拟除虫菊酯会对生态造成危害。B.pulchella幼虫的生化终点显示,在纳克/升的范围内,溴氰菊酯会产生显著的反应;这些反应对于纯产品或配制产品是不同的,并且在浓度较高时是可变的。主成分分析证实,在最低的高效氯氟氰菊酯浓度下,生化反应作为早期终点的普遍性;综合生物标记反应指数随拟除虫菊酯浓度的增加而增加,纯品和配方产品的情况类似。我们得出的结论是,从环境角度来看,高效氯氟氰菊酯值得关注,尤其是对自生无尾类动物的发展而言。我们的研究中包含的一系列生化生物标志物显示出一致的综合生物标志物反应,表明这是一种监测对两栖动物影响的有效工具。环境毒物化学 2024;00:1-11。© 2024 SETAC.
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Biomarkers at the Individual and Biochemical Level: Effects of Pure and Formulated Lambda-Cyhalothrin in Boana pulchella Tadpoles (Duméril and Bibron, 1841)

We compared the effects of lambda-cyhalothrin as the pure active ingredient and as a formulated product (Zero®), on the larval stage of the autochthonous species Boana pulchella. We evaluated ecotoxicological endpoints, behavioral and developmental alterations, and the biochemical detoxifying, neurotoxic, and oxidative stress responses, covering a wide concentration range from environmental to high application levels. Both pyrethroid preparations displayed similar ecotoxicity (median lethal concentration of ~0.5 mg/L), with the lethal effect of Zero® being more pronounced than that of the active ingredient. Sublethal behavioral alterations in natatory activity were observed at 1000 times lower concentrations, indicating the ecological hazard of tadpole exposure to this pyrethroid at environmentally relevant concentrations. Biochemical endpoints in B. pulchella larvae showed significant responses to lambda-cyhalothrin in the ng/L range; these responses were different for the pure or the formulated product, and they were variable at higher concentrations. Principal components analysis confirmed the prevalence of biochemical responses as early endpoints at the lowest lambda-cyhalothrin concentrations; the Integrated Biomarker Response Index proportionally increased with pyrethroid concentration in a similar way for the pure and the formulated products. We conclude that lambda-cyhalothrin is of concern from an environmental perspective, with particular emphasis on autochthonous anuran development. The battery of biochemical biomarkers included in our study showed a consistent integrated biomarker response, indicating that this is a potent tool for monitoring impacts on amphibians. Environ Toxicol Chem 2024;43:2134–2144. © 2024 SETAC

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来源期刊
CiteScore
7.40
自引率
9.80%
发文量
265
审稿时长
3.4 months
期刊介绍: The Society of Environmental Toxicology and Chemistry (SETAC) publishes two journals: Environmental Toxicology and Chemistry (ET&C) and Integrated Environmental Assessment and Management (IEAM). Environmental Toxicology and Chemistry is dedicated to furthering scientific knowledge and disseminating information on environmental toxicology and chemistry, including the application of these sciences to risk assessment.[...] Environmental Toxicology and Chemistry is interdisciplinary in scope and integrates the fields of environmental toxicology; environmental, analytical, and molecular chemistry; ecology; physiology; biochemistry; microbiology; genetics; genomics; environmental engineering; chemical, environmental, and biological modeling; epidemiology; and earth sciences. ET&C seeks to publish papers describing original experimental or theoretical work that significantly advances understanding in the area of environmental toxicology, environmental chemistry and hazard/risk assessment. Emphasis is given to papers that enhance capabilities for the prediction, measurement, and assessment of the fate and effects of chemicals in the environment, rather than simply providing additional data. The scientific impact of papers is judged in terms of the breadth and depth of the findings and the expected influence on existing or future scientific practice. Methodological papers must make clear not only how the work differs from existing practice, but the significance of these differences to the field. Site-based research or monitoring must have regional or global implications beyond the particular site, such as evaluating processes, mechanisms, or theory under a natural environmental setting.
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Correction. Spotlights are papers selected by editors published in peer-reviewed journals that may be more regionally specific or appearing in languages other than English Issue Information - Cover Editorial Board and Table of Contents Detection and Prediction of Toxic Aluminum Concentrations in High-Priority Salmon Rivers in Nova Scotia.
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