抗药性状态:黎巴嫩抗菌药耐药性的病原微生物和环境方法。

IF 1.6 3区 哲学 Q1 HISTORY & PHILOSOPHY OF SCIENCE History and Philosophy of the Life Sciences Pub Date : 2024-08-01 DOI:10.1007/s40656-024-00624-8
Louis-Patrick Haraoui, Anthony Rizk, Hannah Landecker
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引用次数: 0

摘要

本文以黎巴嫩贝鲁特美国大学医疗中心(AUBMC)为具体案例,利用机构历史记录、访谈和学生论文,描绘了医院获得性疾病、抗菌药耐药性(AMR)的出现、武装冲突环境以及更广泛的社会治理问题之间的交叉点。当代科学研究将非临床环境理解为 AMR 历史和发展的一个基本方面,我们借鉴了这种研究方法,将医院视为不仅嵌套在一系列社会和环境背景中,而且经常包含社会和环境历史元素的地方。黎巴嫩的 AMR 与最初制定全球感染控制协议或耐药院内爆发风险因素识别标准的环境有很大不同。虽然这种差异常常被描述为中低收入国家(LMIC)未能保持普遍标准,但我们面前的历史问题却恰恰相反:AMR 和医院感染控制的所谓普遍标准为何未能考虑到社会和环境条件,而这些条件显然对耐药性的演变和传播有着深远影响?战争是一种有组织的混乱状态,社会、环境和临床因素在其中发生了巨大变化,病人转院的社会和政治地形,以及地方和全球环境之间缺失的 "中观 "AMR 监控,这些因素都是我们关注的重点,我们要说明的是,历史上的多部门方法论,尤其是打破了以欧美背景下的 AMR 故事为核心的传统方法论,如何能够丰富针对 AMR 的多部门 "同一健康 "方法。
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States of Resistance: nosocomial and environmental approaches to antimicrobial resistance in Lebanon.

Drawing on institutional historical records, interviews and student theses, this article charts the intersection of hospital acquired illness, the emergence of antimicrobial resistance (AMR), environments of armed conflict, and larger questions of social governance in the specific case of the American University of Beirut Medical Center (AUBMC) in Lebanon. Taking a methodological cue from approaches in contemporary scientific work that understand non-clinical settings as a fundamental aspect of the history and development of AMR, we treat the hospital as not just nested in a set of social and environmental contexts, but frequently housing within itself elements of social and environmental history. AMR in Lebanon differs in important ways from the settings in which global protocols for infection control or rubrics for risk factor identification for resistant nosocomial outbreaks were originally generated. While such differences are all too often depicted as failures of low and middle-income countries (LMIC) to maintain universal standards, the historical question before us is quite the reverse: how have the putatively universal rubrics of AMR and hospital infection control failed to take account of social and environmental conditions that clearly matter deeply in the evolution and spread of resistance? Focusing on conditions of war as an organized chaos in which social, environmental and clinical factors shift dramatically, on the social and political topography of patient transfer, and on a missing "meso" level of AMR surveillance between the local and global settings, we show how a multisectoral One Health approach to AMR could be enriched by an answering multisectoral methodology in history, particularly one that unsettles a canonical focus on the story of AMR in the Euro-American context.

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来源期刊
History and Philosophy of the Life Sciences
History and Philosophy of the Life Sciences 综合性期刊-科学史与科学哲学
CiteScore
2.60
自引率
5.00%
发文量
58
期刊介绍: History and Philosophy of the Life Sciences is an interdisciplinary journal committed to providing an integrative approach to understanding the life sciences. It welcomes submissions from historians, philosophers, biologists, physicians, ethicists and scholars in the social studies of science. Contributors are expected to offer broad and interdisciplinary perspectives on the development of biology, biomedicine and related fields, especially as these perspectives illuminate the foundations, development, and/or implications of scientific practices and related developments. Submissions which are collaborative and feature different disciplinary approaches are especially encouraged, as are submissions written by senior and junior scholars (including graduate students).
期刊最新文献
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