1999-2018 年丹麦脑震荡发病率和流行率:全国队列研究》。

IF 3.9 2区 医学 Q1 CLINICAL NEUROLOGY Journal of neurotrauma Pub Date : 2024-09-05 DOI:10.1089/neu.2024.0217
Peter Preben Eggertsen, Pia Cordsen, Jens Lauritsen, Søren Paaske Johnsen, Jørgen Feldbæk Nielsen
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引用次数: 0

摘要

脑震荡是急诊室的常见诊断,但当代的发病率和流行率估计却很少,而且依赖于自我报告的数据。为了提供最新信息,我们开展了一项全国范围的队列研究,涵盖了1999年至2018年期间的所有丹麦人口。研究人员从丹麦国家患者登记处(DNPR)检索到了诊断为脑震荡的医院接触者,包括急诊就诊、入院和门诊接触者,并对发病率进行了年龄标准化和分层。20年发病率定义为自1999年以来经历过脑震荡的2018年在世丹麦人的百分比。使用的诊断代码为ICD-10代码S06.0和丹麦当地的 "脑震荡观察 "代码(DZ033D)。有关脑震荡伤害活动的其他数据是通过 DNPR 从欧登塞大学医院事故分析小组获得的。研究结果表明,在 1999-2018 年期间,年龄标准化脑震荡总发病率增加了 10%,达到每 10 万人年 308 例(95% 置信区间 (CI):304-313)。值得注意的时间趋势包括:1)性别差异从 40% 降至 6%(95% 置信区间:3%-9%);2)0-1 岁儿童和 80 岁以上老年人的发病率翻了一番;3)除儿童外,所有年龄组的头部成像利用率均有所上升;4)交通相关脑震荡的比例有所下降;5)2018 年脑震荡患病率为 4.9%(95% 置信区间:4.89% - 4.93%)。鉴于人口老龄化,老年人脑震荡发病率的增加令人担忧,值得进一步调查,因为已有针对跌倒的循证预防干预措施。此外,除儿童外,所有年龄组的头部成像使用率均有所上升,这需要注意避免不必要的辐射暴露。尽管与交通有关的病例有所减少,但脑震荡的发病率仍然很高。总之,这些研究结果表明,脑震荡是一个重要的公共卫生问题,有必要进行持续监测、研究和有针对性的资源分配,以有效解决脑震荡管理和预防问题。
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Incidence and Prevalence of Concussion in Denmark from 1999 to 2018: A Nationwide Cohort Study.

Concussion is a common diagnosis in emergency rooms, yet contemporary incidence and prevalence estimates are sparse and rely on self-reported data. A nationwide cohort study was conducted to provide up-to-date information, covering the entire Danish population from 1999 to 2018. Hospital contacts with a concussion diagnosis, including emergency room visits, hospital admissions, and outpatient contacts, were retrieved from the Danish National Patient Registry (DNPR), and incidence rates were age-standardized and stratified. The 20-year prevalence was defined as the percentage of Danes alive in 2018 who had experienced a concussion since 1999. The diagnostic codes used were the ICD-10 code S06.0 and a local Danish code for 'observation for concussion' (DZ033D). Additional data on activities related to concussion injuries were obtained from the Accident Analysis Group at Odense University Hospital through DNPR. Findings from the study showed that during the period 1999-2018, the total age-standardized concussion incidence rate increased by 10% to 308 per 100,000 person-years (95% confidence interval [CI]: 304-313). Notable time trends included (1) a reduced sex difference from 40% to 6% (95% CI: 3%-9%), (2) a doubled incidence rate in children aged 0-1 and in seniors aged over 80, (3) an increased utilization of head imaging across all age groups, except children, (4) a decline in the proportion of traffic-related concussions, and (5) a prevalence of concussion of 4.9% (95% CI: 4.89%-4.93%) in 2018. The increasing incidence of concussions among the elderly is concerning in light of an aging population and warrants further investigation, as evidence-based preventive interventions for falls exist. In addition, the increased utilization of head imaging across all age groups except children calls for attention toward avoidance of unnecessary radiation exposure. Despite a drop in traffic-related cases, concussions remain highly prevalent. In conclusion, these findings indicate that concussions are an important public health concern, necessitating ongoing surveillance, research, and targeted resource allocation to address concussion management and prevention effectively.

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来源期刊
Journal of neurotrauma
Journal of neurotrauma 医学-临床神经学
CiteScore
9.20
自引率
7.10%
发文量
233
审稿时长
3 months
期刊介绍: Journal of Neurotrauma is the flagship, peer-reviewed publication for reporting on the latest advances in both the clinical and laboratory investigation of traumatic brain and spinal cord injury. The Journal focuses on the basic pathobiology of injury to the central nervous system, while considering preclinical and clinical trials targeted at improving both the early management and long-term care and recovery of traumatically injured patients. This is the essential journal publishing cutting-edge basic and translational research in traumatically injured human and animal studies, with emphasis on neurodegenerative disease research linked to CNS trauma.
期刊最新文献
Intravenous Immunomodulatory Nanoparticles Prevent Secondary Damage after Traumatic Brain Injury. Altered Dynamic Brain Functional Network Connectivity Related to Visual Network in Spinal Cord Injury. Genetic Differences Modify Anesthetic Preconditioning of Traumatic Brain Injury in Drosophila. Measuring Self-Efficacy for Concussion Recovery: Psychometric Characteristics of the Progressive Activities of Controlled Exertion-Self-Efficacy Scale. Correction to: Impact of Low-Level Blast Exposure on Brain Function after a One-Day Tactile Training and the Ameliorating Effect of a Jugular Vein Compression Neck Collar Device; DOI: 10.1089/neu.2018.5737.
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