埃塞俄比亚东北部南沃洛区公立医院收治的 6 至 59 个月大儿童患社区获得性重症肺炎后的康复时间及其预测因素:一项前瞻性随访研究。

IF 8.5 Q1 RESPIRATORY SYSTEM Pneumonia Pub Date : 2024-08-05 DOI:10.1186/s41479-024-00135-x
Mekonnen Teferi, Elsabeth Addisu, Shambel Wodajo, Amare Muche, Abel Endawekie, Bezawit Adane, Tilahun Dessie, Natnael Kebede
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引用次数: 0

摘要

导言:埃塞俄比亚是社区获得性肺炎发病率较高的国家之一,五岁以下儿童是肺炎尤其是严重社区获得性肺炎的高发人群。然而,有关五岁以下儿童康复时间及其预测因素的研究却很有限,而且大多数研究都是回顾性的,未能解决影响康复时间的重要变量。因此,本研究旨在估算埃塞俄比亚东北部南沃洛区公立医院收治的五岁以下儿童康复时间的中位数及其预测因素:方法:2021 年 3 月 10 日至 5 月 10 日,对 270 名研究对象进行了一项基于医院的前瞻性队列研究。研究采用了系统随机抽样技术。通过访谈和病历审查收集数据。数据分别使用 Epi Data 3.1 版和 STATA 14.0 版进行输入和分析。采用 Kaplan-Meier 和 Cox 回归模型检验重症社区获得性肺炎康复的时间和预测因素:结果:重症社区获得性肺炎的总康复率(95% 置信区间)为每 100 个观察日 20.45(17.84-23.46)例,中位(IQR)康复时间为 [3, 5] 天。重症社区获得性肺炎康复时间的预测因素为入院时有合并症[AHR = 0.49 (95%CI: 0.32,0.75)]、发病 5 天后到达医院[AHR = 0.35 (95%CI: 0.20,0.60)]、臂中上臂围 结论和建议:总体而言,研究地区严重社区获得性肺炎患儿的康复时间符合推荐的国家标准。在治疗过程中,应适当关注存在已确定预测因素的儿童。
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Time to recovery from severe community-acquired pneumonia and its predictors among 6 to 59 months of age children admitted to South Wollo zone public hospitals, North East Ethiopia: a prospective follow-up study.

Introduction: Ethiopia is one of those countries with higher burden of community acquired pneumonia among its people, under five children are the members of society that are highly affected by pneumonia particularly Severe Community Acquired Pneumonia. However, there are limited studies on time to recovery and its predictors in under-five children and most of them are retrospective which fails to address important variables that affect the time to recovery. Therefore, the aim of this study was to estimate the median time to recovery and its predictors among under five children admitted to South Wollo zone public hospitals, North East Ethiopia.

Methods: An institution-based prospective cohort study was conducted from March 10 to May 10, 2021, with 270 study subjects. A systematic random sampling technique was used. Data was collected by interview and chart review. The data were entered and analyzed using Epi Data version 3.1 and STATA version 14.0, respectively. Kaplan-Meier and Cox regression models were used to test the time and predictors of recovery from severe community-acquired pneumonia.

Results: The overall incidence of recovery rate (95% confidence interval) from Severe Community-Acquired Pneumonia was 20.45(17.84-23.46) per 100 person days observation with median (IQR) time to recovery of [3, 5] days. The predictors of time to recovery from Severe Community-Acquired Pneumonia were having comorbidities on admission [AHR = 0.49 (95%CI: 0.32,0.75)], reaching hospitals after 5 days of onset of symptoms [AHR = 0.35 (95%CI: 0.20,0.60)], having Middle Upper Arm Circumference < = 12.5 cm [AHR = 0.21 (95%CI: 0.12,0.37)], the presence of smoker in the house [AHR = 0.21 (95%CI: 0.10,0.42)] and being not fully immunized for age [AHR = 0.35 (95%CI: 0.24,0.53)].

Conclusion and recommendations: Generally the recovery time of children with Severe Community Acquired Pneumonia in the study area was within the recommended national standards. Due attention should be given to children with the identified predictors while treating them.

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Pneumonia
Pneumonia RESPIRATORY SYSTEM-
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1.50%
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11 weeks
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