[人类乳头瘤病毒 18 型--悼念]。

Lakartidningen Pub Date : 2024-08-06
Joakim Dillner
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引用次数: 0

摘要

在瑞典,19% 的宫颈癌病例是由 HPV 18 引起的,尤其是腺癌。要消灭致癌性最强的 HPV 类型,如 HPV 16 和 HPV 18,需要较高的疫苗接种覆盖率,而中等致癌性的病毒,如 HPV 31、33、45、52 和 58,由于繁殖数量较少,则更容易消灭。1994-1998 年出生的女性在 13-18 岁时可接种 HPV 16 和 HPV 18 的补种疫苗,但只有约 55% 的人接种,不足以消灭这些病毒。如果为 1994-1998 年出生的女性提供 HPV 16、18、31、33、45、52 和 58 疫苗接种,并达到约 70% 的参与率,那么就能消灭中等致癌病毒,并实现对 HPV 16/18 的群体免疫。自 2021 年起,一个针对这些 HPV 类型提供免费疫苗和筛查的国家项目正在进行中。在项目开始时,疫苗接种覆盖率高的年龄组中只有一例人乳头瘤病毒 18,这意味着这种病毒即将灭绝。
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[Human papillomavirus type 18 - In memoriam].

HPV 18 caused 19  percent of all cervical cancer cases in Sweden, in particular adenocarcinomas. High vaccination coverages are required to eliminate the most oncogenic HPV types like HPV 16 and HPV 18, while medium-oncogenic viruses such as HPV 31, 33, 45, 52, and 58 are easier to eliminate due to their lower reproduction number. Women born 1994-1998 were offered catch-up vaccination against HPV 16 and HPV 18 at ages 13-18, but only about 55 percent participated, which is insufficient to eliminate these viruses. Offering vaccination against HPV 16, 18, 31, 33, 45, 52, and 58 to women born in 1994-1998 and achieving around 70 percent participation should eliminate the medium-oncogenic viruses and achieve population immunity also for HPV 16/18. A national project offering free vaccines and screening against these HPV types is ongoing since 2021. Already at the start of the project, there was only a single case of HPV 18 in age groups with high vaccination coverage, implying that extinction of this virus is imminent.

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来源期刊
Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
134
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