2023 年中国儿童 SARS-CoV-2 和流感的感染率和症状比例。

IF 7.2 2区 医学 Q1 IMMUNOLOGY Emerging Infectious Diseases Pub Date : 2024-09-01 Epub Date: 2024-08-06 DOI:10.3201/eid3009.240065
Chao Shi, Yuhe Zhang, Sheng Ye, Jiyang Zhou, Fuyu Zhu, Yumeng Gao, Yan Wang, Bingbing Cong, Shuyu Deng, You Li, Bing Lu, Xin Wang
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引用次数: 0

摘要

我们在中国无锡的托儿所和学校开展了一项关于 SARS-CoV-2 和流感发病率的纵向队列研究,在 2023 年 2 月至 6 月期间每周收集 1,760 份环境样本和 9,214 份来自 593 名学生(无论有无症状)的咽拭子。我们估计,SARS-CoV-2 的累计感染率为 124.8(74 次)/1,000 人,流感的累计感染率为 128.2(76 次)/1,000 人。18 岁人群的 SARS-CoV-2 感染率最高,4 岁儿童的流感感染率最高。无症状的 SARS-CoV-2 感染者比例为 59.6%,流感感染者比例为 66.7%;16-18 岁儿童出现 SARS-CoV-2 症状的比例低于 4-6 岁儿童。只有从经常接触的物体表面采集的样本对 SARS-CoV-2 (4/1,052)和流感(1/1,052)检测呈阳性。我们发现,SARS-CoV-2 和流感的流行模式不同步,这与全国哨点监测的趋势相似。这些结果支持在儿科人群中接种疫苗和采取其他干预措施,如在教育场所进行环境消毒。
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Infection Rates and Symptomatic Proportion of SARS-CoV-2 and Influenza in Pediatric Population, China, 2023.

We conducted a longitudinal cohort study of SARS-CoV-2 and influenza rates in childcare centers and schools in Wuxi, China, collecting 1,760 environmental samples and 9,214 throat swabs from 593 students (regardless of symptoms) in weekly collections during February-June 2023. We estimated a cumulative infection rate of 124.8 (74 episodes)/1,000 persons for SARS-CoV-2 and 128.2 (76 episodes)/1,000 persons for influenza. The highest SARS-CoV-2 infection rate was in persons 18 years of age, and for influenza, in children 4 years of age. The asymptomatic proportion of SARS-CoV-2 was 59.6% and 66.7% for influenza; SARS-CoV-2 symptomatic proportion was lower in 16-18-year-olds than in 4-6-year-olds. Only samples from frequently touched surface tested positive for SARS-CoV-2 (4/1,052) and influenza (1/1,052). We found asynchronous circulation patterns of SARS-CoV-2 and influenza, similar to trends in national sentinel surveillance. The results support vaccination among pediatric populations and other interventions, such as environmental disinfection in educational settings.

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来源期刊
Emerging Infectious Diseases
Emerging Infectious Diseases 医学-传染病学
CiteScore
17.30
自引率
1.70%
发文量
505
审稿时长
1 months
期刊介绍: Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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