手术后光电生物调节疗法可改善狗选择性胃切除术后的效果。

IF 2.1 4区 医学 Q3 ENGINEERING, BIOMEDICAL Lasers in Medical Science Pub Date : 2024-08-08 DOI:10.1007/s10103-024-04164-2
J C Alves, Ana Filipe, Ana Santos
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引用次数: 0

摘要

目的:评估狗手术后光生物调节疗法的效果:选取 20 只进行选择性胃切除术的狗,随机分为对照组(CG,n = 10)和 PBMT 组(PBMTG,n = 10)。术前用药包括美托咪定和丁吗啡诺。手术前使用美洛昔康。使用异丙酚进行诱导,并用七氟醚维持。使用利多卡因进行局部阻滞。所有动物都进行了切胃手术。PBMTG 在术后立即接受了 PBMT。在气管插管后1、2、4、6、8、12、16、20和24小时,使用格拉斯哥综合疼痛量表-简表(CMPS-SF)收集动物术后是否需要镇痛、评估时是否进食以及疼痛评分。用 Mann-Whitney 检验比较 CMPS-SF 评分,用 χ2 检验比较需要镇痛抢救和进食的动物比例。P 为结果:没有任何动物需要镇痛抢救。尽管如此,在拔管后 1 至 4 小时内,CG 和 PBMTG 的 CMPS-SF 评分仍存在明显差异。在拔管后8小时的评估中,PBMTG动物进食的比例明显更高:结论:与单独使用标准方案相比,在标准麻醉和镇痛方案中加入术后光生物调节可降低CMPS-SF评分,提高动物恢复进食的比例。
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Post-surgical photobiomodulation therapy improves outcomes following elective gastropexy in dogs.

Purpose: To evaluate the effect of post-surgical photobiomodulation therapy in dogs.

Methods: Twenty dogs were selected for elective gastropexy and randomly divided into a control (CG, n = 10) and a PBMT group (PBMTG, n = 10). Pre‑medication consisted of medetomidine and butorphanol. Meloxicam was administered before the procedure. Induction was performed with propofol and maintained with sevoflurane. Local blocks with lidocaine were used. Incisional gastropexy was performed in all animals. PBMTG received PBMT immediately after surgery. The need for postoperative rescue analgesia, if the animal had eaten by the evaluation momen, and pain scores were collected using the Glasgow Composite Measure Pain Scale - Short Form (CMPS‑SF) at 1, 2, 4, 6, 8, 12, 16, 20, and 24 h post‑endotracheal extubation. CMPS‑SF scores were compared with the Mann-Whitney Test and proportions of animals that required rescue analgesia and had eaten with a χ2 test. P was set at < 0.05.

Results: No rescue analgesia was needed for any animal. Still, significant differences were observed in CMPS-SF scores between CG and PBMTG between 1 and 4 h post-extubation. PBMTG had a significantly higher proportion of animals eating up to the 8 h post-extubation evaluation moment.

Conclusion: Adding post-surgical photobiomodulation to a standard anesthesia and analgesia protocol reduced CMPS-SF scores and increased the proportion of animals that resumed eating compared to the standard protocol alone.

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来源期刊
Lasers in Medical Science
Lasers in Medical Science 医学-工程:生物医学
CiteScore
4.50
自引率
4.80%
发文量
192
审稿时长
3-8 weeks
期刊介绍: Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.
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