骨软骨异体移植(OCA)和自体软骨细胞植入(ACI)都是治疗髌股关节软骨缺损的重要方法。

Andreas H Gomoll, Sabrina M Strickland
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引用次数: 0

摘要

髌骨股骨(PF)是软骨修复的难点。虽然骨软骨同种异体移植(OCA)和自体软骨细胞植入(ACI)都已被确定为软骨修复的标准疗法,但大多数治疗算法仍倾向于对髌股关节进行ACI,因为ACI的成功率很高。但如今,OCA已成为修复先前失败的PF软骨修复术的首选疗法。在这种情况下取得的积极疗效鼓励将OCA用于特定的初次软骨修复患者,即缺损未愈合或骨软骨缺损的患者。与 ACI 相比,OCA 的优势在于组织更坚固,可能不需要通过截骨来减轻 PF 关节的负荷。即使是 ACI,TTO 也只适用于髌骨跟踪异常和/或髌骨高度异常的患者。就重返运动场而言,需要有现实的期望。据报道,NFL 球员的恢复率为 67%,平均年龄为 32 岁的普通人群的恢复率为 54%。ACI 和 OCA 都是治疗膝关节软骨缺损的重要方法。
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Editorial Commentary: Both Osteochondral Allograft Transplantation and Autologous Chondrocyte Implantation Are Valuable Treatment Options for Patellofemoral Joint Cartilage Defects.

The patellofemoral (PF) joint is a challenging location to repair cartilage. Although both osteochondral allograft transplantation (OCA) and autologous chondrocyte implantation (ACI) are established as standard therapies for cartilage repair, most treatment algorithms continue to favor ACI for the PF joint, which shows a high rate of success. Today, however, OCA is a treatment of choice to revise prior failed PF cartilage repair. The positive outcomes in this setting encourage indicating OCA for select primary cartilage repair patients, namely those with defects that are uncontained or osteochondral. An advantage of OCA over ACI is that the tissue is more robust and there may be less need for osteotomy to unload the PF joint. Even for ACI, tibial tubercle osteotomy is reserved for patients with abnormal patellar tracking and/or patellar height. In terms of return to sports, realistic expectations are required. Both ACI and OCA are valuable treatment options for PF cartilage defects.

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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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