用乌达帕替尼和 NB-UVB 治疗儿童难治性节段型白癜风和斑秃：病例报告。

IF 1.9 4区医学 Q3 DERMATOLOGY Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-08-06 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S467026

Yuzhu Mu, Ting Pan, Lingling Chen

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引用次数: 0

摘要

白癜风和斑秃都是自身免疫性皮肤病，同时发病的几率非常低。传统的治疗方法通常包括糖皮质激素，但长期使用糖皮质激素会产生许多不良反应，而且很难达到满意的效果。由于致病途径部分重叠，乌达替尼对白癜风和斑秃均有疗效。我们报告了乌达替尼联合紫外线成功治疗一名九岁儿童白癜风合并斑秃的病例。白癜风和斑秃的面积明显缩小，取得了令人满意的疗效。这为治疗儿童白癜风合并斑秃提供了一个新思路。

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Treatment of Refractory Segmental Vitiligo and Alopecia Areata in a Child with Upadacitinib and NB-UVB: A Case Report.

Vitiligo and alopecia areata are both autoimmune skin diseases, and the chances of co-occurrence are very low. Conventional treatments often include glucocorticoids, which have many adverse reactions with long-term use and are difficult to achieve satisfactory results. Upadacitinib has been found to be effective in both vitiligo and alopecia areata due to partial overlap in pathogenic pathways. We report the successful treatment of vitiligo combined with alopecia areata in a nine-year-old child with upadacitinib in combination with UVB. The area of vitiligo and alopecia areata decreased significantly, and satisfactory results were obtained. It provides a new idea for the treatment of vitiligo complicated with alopecia areata in children.

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.