脉冲振荡测量法在识别退伍军人队列中限制性肺缺陷方面的性能。

Q3 Medicine Open Respiratory Medicine Journal Pub Date : 2024-07-19 eCollection Date: 2024-01-01 DOI:10.2174/0118743064304109240611054726
Danielle R Glick, Clayton H Brown, Lan Li, Patricia Gucer, Joanna M Gaitens, Melissa A McDiarmid, Stella E Hines
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引用次数: 0

摘要

背景:脉冲振荡测量法(IOs)是一种用于评估肺功能的技术,它利用声波在潮式呼吸中的强加作用来描述气道和肺实质的特征。IOs 在识别阻塞性肺缺陷方面特别有用。本分析报告旨在探讨 IOs 在一组暴露于贫铀(DU)的第一次海湾战争退伍军人中限制性肺生理学鉴定中的应用:方法:在一个动态的 85 名退伍军人队列中,共有 36 人参加了 2019 年的亲自监测访问,并完成了 IOs 和 PFTs。在对该组总体情况进行横断面分析时,对 IOs 的表现进行了评估,并评估了根据肺活量测定(FEV1/FVC ≥ LLN 和 FVC < LLN)或肺容积测定(TLC < LLN)确定的限制性肺缺陷患者的 IOs 表现:共有 6 人被确定为肺功能受限(其中 4 人仅根据肺活量测定,另外 2 人根据肺活量测定)。当存在肺功能受限时,阻力和反应的 IOs 值明显异常:结论:在肺功能评估中,肺活量检查可能比肺功能检查更有优势,因为肺活量检查操作更快,而且不需要费力气。尽管人们对 IOs 在识别限制性肺生理学方面的效用知之甚少,但我们的研究结果支持使用 IOs。
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Performance of Impulse Oscillometry in Identifying Restrictive Lung Defects in a Veteran Cohort.

Background: Impulse oscillometry (IOs) is a technique used to evaluate lung function that uses sound waves imposed over tidal breathing to characterize the airways and lung parenchyma. IOs has been particularly useful in the identification of obstructive lung defects. The present analysis seeks to explore the use of IOs in the identification of restrictive lung physiology among a group of Gulf War I veterans exposed to depleted uranium (DU).

Methods: A total of 36 out of a dynamic 85-veteran cohort attended in-person surveillance visits in 2019 and completed both IOs and PFTs. Performance on IOs was evaluated in a cross-sectional analysis of the group overall and in those identified as having restrictive lung defects defined by either spirometry (FEV1/FVC ≥ LLN and FVC < LLN) or lung volumes (TLC < LLN).

Results: A total of 6 individuals were identified as having restriction (4 based on spirometry alone and an additional 2 by lung volumes). When restriction was present, IOs values of both resistance and reactance were significantly more abnormal.

Conclusion: In the assessment of lung function, IOs may be advantageous over PFTs because it is faster to perform and effort-independent. Although little is known about the utility of IOs in identifying restrictive lung physiology, our results support its use.

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来源期刊
Open Respiratory Medicine Journal
Open Respiratory Medicine Journal Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.70
自引率
0.00%
发文量
17
期刊介绍: The Open Respiratory Medicine Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in respiratory medicine. Topics covered include: -COPD- Occupational disorders, and the role of allergens and pollutants- Asthma- Allergy- Non-invasive ventilation- Therapeutic intervention- Lung cancer- Lung infections respiratory diseases- Therapeutic interventions- Adult and paediatric medicine- Cell biology. The Open Respiratory Medicine Journal, a peer reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available worldwide.
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