诺卡氏菌角膜炎:临床诊断与成功结果

Q3 Medicine Oman Journal of Ophthalmology Pub Date : 2024-06-27 eCollection Date: 2024-05-01 DOI:10.4103/ojo.ojo_175_23
Dubbaka Srujana, Sandeep Shankar, Kavita Bala Anand, Mohini Agrawal, Aanchal Singhal, Ashok Kumar, Divya Kochhar
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引用次数: 0

摘要

诺卡氏角膜炎多见于酗酒、营养不良或感染艾滋病毒的患者。该病的病程呈慢性徘徊状态,因此很难诊断。一名 53 岁的男性患者在过去 3 周内出现右眼疼痛和发红。角膜中央旁有溃疡,基质浸润,多个卫星病变呈花环状,提示为诺卡菌感染。角膜刮除后,开始使用强化阿米卡星、莫西沙星和环磷酰胺。革兰氏染色显示为丝状、分支革兰氏阳性菌,Ziehl-Neelsen 染色显示为耐酸菌,证实了我们的临床诊断。溃疡在 6 周内完全消退。由此可见,高度的临床怀疑和微生物学证实有助于快速处理,确保了患者的成功。
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Nocardia keratitis: A clinical diagnosis with successful outcome.

Nocardia keratitis is mostly seen in patients with alcoholism, malnutrition, or HIV. Its chronic waxing-and-waning course makes it difficult to diagnose. A 53-year-old male presented with pain and redness in his right eye for the past 3 weeks. The cornea had paracentral ulcer with stromal infiltrates and multiple satellite lesions giving wreath-like appearance suggestive of Nocardia. After corneal scraping, fortified amikacin, moxifloxacin, and cycloplegics were started. Gram stain revealed filamentous, branching Gram-positive bacteria and acid-fast on Ziehl-Neelsen stain confirming our clinical diagnosis. Ulcer completely resolved over 6 weeks. Thus, a high index of clinical suspicion which was further backed by microbiological confirmation aided in expedient management ensuring a successful outcome.

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来源期刊
Oman Journal of Ophthalmology
Oman Journal of Ophthalmology Medicine-Ophthalmology
CiteScore
0.50
自引率
0.00%
发文量
68
审稿时长
50 weeks
期刊介绍: To provide a platform for scientific expression of the Oman Ophthalmic Society and the international Ophthalmic community and to provide opportunities for free exchange of ideas and information. To serve as a valuable resource for ophthalmologists, eye-care providers including optometrists, orthoptists, other health care professionals and research workers in all aspects of the field of visual science.
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