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Brittle cornea syndrome: Integrating unique presentations and novel management options. 脆角膜综合征:整合独特的表现和新的管理方案。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_260_24
Jyothi Balakrishnan, Aafreen Bari, Prafulla Kumar Maharana, Tushar Agarwal, Tanuj Dada, Namrata Sharma

Brittle cornea syndrome (BCS) is a connective tissue disorder with a vast majority of clinical presentations and prognostic outcomes. This case series highlights various ocular presentations, their responses to treatment strategies, and final visual outcomes. It was an observational case series at a tertiary eye care center. Three patients with BCS and different corneal pathologies were managed and studied. The first case presented with wound dehiscence, a shallow anterior chamber, and a disenclaved iris claw lens. He underwent intraocular lens (IOL) explantation and wound closure using cyanoacrylate glue and a bandage contact lens. The second case involved corneal ectasia with rupture and an intumescent cataract, along with lens-endothelial touch. He underwent lens aspiration with posterior chamber IOL implantation and epi-keratoplasty with a biosynthetic cornea. However, the biosynthetic cornea had to be removed due to a severe inflammatory reaction following the procedure. The patient was later rehabilitated with deep anterior lamellar keratoplasty. The third patient presented with bilateral tractional descemet membrane detachment resulting from multiple minor injuries. Refraction with prescription glasses was used for visual rehabilitation. In conclusion, the management of BCS requires individualized treatment strategies tailored to each patient's presentation and response.

角膜脆性综合征(BCS)是一种结缔组织疾病,具有绝大多数的临床表现和预后结果。这个病例系列强调了各种眼部表现,他们对治疗策略的反应,以及最终的视力结果。这是一个三级眼科保健中心的观察性病例系列。对3例不同角膜病理的BCS患者进行治疗和研究。第一例患者表现为伤口裂开,前房浅,虹膜爪状晶状体脱落。他接受了人工晶状体(IOL)植入术,并使用氰基丙烯酸酯胶和绷带隐形眼镜缝合伤口。第二个病例涉及角膜扩张并破裂和膨胀性白内障,并伴有晶状体内皮接触。他接受了晶状体吸出和后房型人工晶状体植入术以及生物合成角膜角膜移植手术。然而,由于手术后严重的炎症反应,生物合成角膜不得不被移除。患者后来接受了深前板层角膜移植术。第三例患者表现为双侧牵引性下网膜脱离,造成多处轻伤。使用处方眼镜屈光进行视力康复。总之,BCS的管理需要针对每个患者的表现和反应量身定制个性化的治疗策略。
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引用次数: 0
Comment on: Knowledge, attitude, and practice among kindergarten teachers regarding vision and eye screening of preschool children. 点评:幼儿园教师对学龄前儿童视力和眼睛筛查的知识、态度和实践。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_33_25
Vishal Biswas, Roshni Majumder, Supriya Awasthi
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引用次数: 0
Macular edema after pars plana vitrectomy for primary rhegmatogenous retinal detachment: Incidence, morphology, and risk factors. 原发孔源性视网膜脱离的玻璃体切除后黄斑水肿:发生率、形态和危险因素。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_347_24
D S Hamsa, Jacob Chacko, Hegde Sharat Shivaramaiah, Krishnaprasad Kudlu

Purpose: To study the incidence, morphology, and factors affecting macular edema after pars plana vitrectomy (PPV) for primary rhegmatogenous retinal detachment (RRD).

Study design: Retrospective study.

Materials and methods: The study was conducted at a single institution over a period of 1 year. Adults who underwent PPV and silicone oil injection for the repair of primary RRD were included in the study. The main outcome measure was the incidence of macular edema at 3 months post surgery.

Results: A total of 45 eyes were included. The incidence of macular edema was found to be 26.66% (12 out of 45), with the most common type being spongiform. Patients with advanced proliferative vitreoretinopathy (PVR) changes at presentation were significantly more prone to develop macular edema (P = 0.007). However, internal limiting membrane peel, duration of RRD, pseudophakia, and macula status were not found to be significant risk factors. Five patients with increased central retinal thickness on optical coherence tomography were given posterior subtenon triamcinolone injections.

Conclusion: Macular edema is a relatively common complication after PPV, with an incidence of 26.66% in our study, which can result in suboptimal visual gain. Severe PVR was found to be a significant risk factor for macular edema.

目的:探讨原发性孔源性视网膜脱离(RRD)术后黄斑水肿的发生率、形态及影响因素。研究设计:回顾性研究。材料和方法:本研究在单一机构进行,为期1年。接受PPV和硅油注射修复原发性RRD的成年人被纳入研究。主要观察指标是术后3个月黄斑水肿的发生率。结果:共纳入45只眼。黄斑水肿发生率为26.66%(12 / 45),以海绵状水肿最为常见。晚期增殖性玻璃体视网膜病变(PVR)患者在就诊时更容易发生黄斑水肿(P = 0.007)。然而,内部限制膜剥离、RRD持续时间、假晶态和黄斑状态并不是显著的危险因素。5例视网膜中央厚度增加的患者在光学相干断层扫描上给予曲安奈德后静脉注射。结论:黄斑水肿是PPV术后较为常见的并发症,本研究发生率为26.66%,可导致视力不佳。重度PVR是黄斑水肿的重要危险因素。
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引用次数: 0
Full-thickness macular hole after uneventful phacoemulsification cataract surgery: Case report and review of literature. 白内障超声乳化手术后全层黄斑裂孔:病例报告及文献复习。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_47_25
Ahmed Omer Kenawy, Mohammed Al-Abri

A 61-year-old healthy female patient underwent an uneventful left phacoemulsification procedure under local anesthesia for a left visually significant senile cataract. One month postoperatively, her decimal visual acuity improved from 0.06 preoperatively to 0.5. However, 3 months postoperatively, the best-corrected visual acuity (BCVA) had decreased to 0.3. Fundus examination revealed the development of a full-thickness macular hole (FTMH). Diagnosis was confirmed by optical coherence tomography of the macula, which demonstrated FTMH. The patient subsequently underwent pars plana vitrectomy with internal limiting membrane peeling using an inverted flap technique, and injection of gas (C3F8 12%) as an endotamponade. Six months postoperatively, she showed a favorable anatomical closure with restoration of the macular contour and visual improvement to 0.63. Timely detection and management of FTMH following phacoemulsification is crucial for optimizing postoperative visual outcome, as this is a rare but serious complication of cataract surgery. The underlying pathophysiology of this condition remains unclear and is believed to be multifactorial. Prompt recognition and appropriate surgical intervention are essential to achieve the best possible visual outcomes in such cases.

一位61岁的健康女性患者在局部麻醉下接受了左侧明显的老年性白内障超声乳化术。术后1个月,患者的十进制视力由术前的0.06提高到0.5。然而,术后3个月,最佳矫正视力(BCVA)下降到0.3。眼底检查发现全层黄斑孔(FTMH)。通过黄斑光学相干断层扫描证实诊断为FTMH。随后,患者接受了玻璃体切割手术,采用倒瓣技术进行内限制膜剥离,并注射气体(C3F8 12%)作为内填塞。术后6个月,患者解剖闭合良好,黄斑轮廓恢复,视力改善至0.63。由于FTMH是白内障手术中一种罕见但严重的并发症,因此及时发现和处理超声乳化术后FTMH对于优化术后视力至关重要。这种情况的潜在病理生理学尚不清楚,被认为是多因素的。在这种情况下,及时识别和适当的手术干预是实现最佳视力结果的必要条件。
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引用次数: 0
Impact of face mask usage on physiological and histological ocular surface features of hydrogel and silicone hydrogel contact lens wearers. 使用口罩对水凝胶和硅酮水凝胶隐形眼镜佩戴者眼表生理和组织学特征的影响。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_34_25
Lavanya Kalikivayi, Anjana Mohandas, Venkataramana Kalikivayi

Background: To assess the impact of prolonged face mask use on the physiological and histological features of the ocular surface in hydrogel and silicone hydrogel contact lens wearers.

Materials and methods: A single-blind cohort study was conducted among neophyte contact lens wearers aged 18-25 years, divided into hydrogel and silicone hydrogel groups. Tear film parameters were evaluated using noninvasive tear breakup time (NITBUT), tear meniscus height (TMH), meibomian gland loss (MGL), ocular redness (OR), and Ocular Surface Disease Index (OSDI) scores. Impression cytology samples from the nasal bulbar conjunctiva were collected using 0.22 μm micropore, 5 mm × 3 mm cellulose acetate filter paper to assess goblet cell count (GCC). Multivariate analyses of variance with Tukey post hoc analysis was used to compare the outcomes between face mask wear and nonwear conditions.

Results: A significant decrease in NITBUT and Schirmer's test, along with increased MGL, was observed in hydrogel contact lens wearers when comparing face mask use to nonuse. No statistically significant changes were noted in TMH, GCC, OSDI, or ocular redness. Similarly, significant reductions in NITBUT and Schirmer's test were found in silicone hydrogel contact lens wearers with face mask wear compared to nonwear. Logistic regression analysis showed no significant association between face mask wear and ocular redness.

Conclusion: Prolonged face mask use may affect ocular surface health, particularly in hydrogel contact lens wearers. Further research is needed to explore interventions to mitigate adverse effects and optimize ocular comfort for individuals wearing face masks for extended periods.

背景:评估长期使用口罩对水凝胶和硅酮水凝胶隐形眼镜配戴者眼表生理和组织学特征的影响。材料与方法:采用单盲队列研究,将18-25岁的隐形眼镜新手分为水凝胶组和硅胶水凝胶组。通过无创撕裂破裂时间(NITBUT)、撕裂半月板高度(TMH)、睑板腺损失(MGL)、眼红肿(OR)和眼表疾病指数(OSDI)评分来评估泪膜参数。采用0.22 μm微孔、5 mm × 3 mm醋酸纤维素滤纸采集鼻球结膜印迹细胞学样本,测定杯状细胞计数(GCC)。采用多变量方差分析和Tukey事后分析来比较戴口罩和不戴口罩的结果。结果:在水凝胶隐形眼镜佩戴者中,NITBUT和Schirmer’s测试显著下降,同时MGL增加,当比较使用面罩和不使用面罩时。TMH、GCC、OSDI或眼部红肿均无统计学意义的变化。同样,与不戴口罩的人相比,戴硅胶水凝胶隐形眼镜的人NITBUT和Schirmer的测试结果也显著降低。Logistic回归分析显示,佩戴口罩与眼部红肿无显著相关性。结论:长期使用口罩可能会影响眼表健康,特别是水凝胶隐形眼镜佩戴者。需要进一步的研究来探索干预措施,以减轻长时间佩戴口罩的不良影响,并优化眼部舒适度。
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引用次数: 0
Reply to comment on "Examining the Competence of Artificial Intelligence Programs in Neuro-ophthalmological Disorders and Analyzing Their Comparative Superiority". 回复“检验人工智能程序在神经眼科疾病中的能力并分析其比较优势”的评论。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_306_25
Eyupcan Sensoy, Mehmet Citirik
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引用次数: 0
Design and validation of the Arabic LogMAR chart, University of Buraimi (UoB) version. 阿拉伯语LogMAR图表的设计与验证,布赖米大学(UoB)版本。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_67_24
Galal Mohamed Ismail, Zoelfigar Mohamed, Babu Noushad, Ahmed Kandil, Badour Ali Al-Shahi

Background: The background of the study was to design and validate an Arabic logMAR (UOB) version chart for testing distance visual acuity based on the constructed principle conceived by Bailey and Lovie chart.

Methods: Selected Arabic alphabets were designed on a 5 × 5 grid to test the visual acuity at 4 m distance. Out of the 28 Arabic alphabets, 10 optotypes with comparable legibility elements were chosen experimentally to construct the chart. The validity and repeatability were examined of the designed against a standard logMAR chart and existing Arabic logMAR (Al Mufarrej) version using the paired t-test.

Results: A total of 14 rows (1.0 to-0.3 logMAR) with five letters in each line were designed with the range of legibility between 1.07913 and 0.993822. The visual acuity score of UOB Arabic logMAR ranged between -0.02 and 0.24 (mean 0.045 ± 0.061. The chart demonstrated no significant difference compared with the standard logMAR (P = 0.248) and Al Mufarrej logMAR version (P = 0.318).

Conclusion: The newly constructed Arabic logMAR UOB version chart has demonstrated good validity and repeatability when compared to the standard logMAR. The statistical differences in visual acuity measurements between the newly Arabic logMAR UOB version chart, and the standard logMAR chart was within the acceptable limits. Likewise, it can be registered, listed, and used to test visual acuity clinically among the literate Arabic population.

背景:本研究的背景是基于Bailey和Lovie表的构造原理,设计并验证阿拉伯语logMAR (UOB)版本的距离视力测试表。方法:将选定的阿拉伯字母设计在5 × 5网格上,测试4 m距离的视敏度。从28个阿拉伯文字母中,实验选取了10个易读元素具有可比性的视型来构建图表。采用配对t检验对设计的标准logMAR图和现有阿拉伯logMAR (Al Mufarrej)版本进行有效性和可重复性检验。结果:共设计14行(1.0 ~ 0.3 logMAR),每行5个字母,易读范围为1.07913 ~ 0.993822。UOB阿拉伯文logMAR视力评分范围为-0.02 ~ 0.24(平均0.045±0.061)。与标准logMAR版本(P = 0.248)和Al Mufarrej logMAR版本(P = 0.318)相比,图表显示无显著差异。结论:新建立的阿拉伯文logMAR UOB版本图与标准logMAR相比具有良好的效度和可重复性。新阿拉伯文logMAR UOB版图与标准logMAR图的视力测量统计差异在可接受范围内。同样,它可以被登记、列出,并用于在识字的阿拉伯人口中临床测试视力。
{"title":"Design and validation of the Arabic LogMAR chart, University of Buraimi (UoB) version.","authors":"Galal Mohamed Ismail, Zoelfigar Mohamed, Babu Noushad, Ahmed Kandil, Badour Ali Al-Shahi","doi":"10.4103/ojo.ojo_67_24","DOIUrl":"10.4103/ojo.ojo_67_24","url":null,"abstract":"<p><strong>Background: </strong>The background of the study was to design and validate an Arabic logMAR (UOB) version chart for testing distance visual acuity based on the constructed principle conceived by Bailey and Lovie chart.</p><p><strong>Methods: </strong>Selected Arabic alphabets were designed on a 5 × 5 grid to test the visual acuity at 4 m distance. Out of the 28 Arabic alphabets, 10 optotypes with comparable legibility elements were chosen experimentally to construct the chart. The validity and repeatability were examined of the designed against a standard logMAR chart and existing Arabic logMAR (Al Mufarrej) version using the paired <i>t</i>-test.</p><p><strong>Results: </strong>A total of 14 rows (1.0 to-0.3 logMAR) with five letters in each line were designed with the range of legibility between 1.07913 and 0.993822. The visual acuity score of UOB Arabic logMAR ranged between -0.02 and 0.24 (mean 0.045 ± 0.061. The chart demonstrated no significant difference compared with the standard logMAR (<i>P</i> = 0.248) and Al Mufarrej logMAR version (<i>P</i> = 0.318).</p><p><strong>Conclusion: </strong>The newly constructed Arabic logMAR UOB version chart has demonstrated good validity and repeatability when compared to the standard logMAR. The statistical differences in visual acuity measurements between the newly Arabic logMAR UOB version chart, and the standard logMAR chart was within the acceptable limits. Likewise, it can be registered, listed, and used to test visual acuity clinically among the literate Arabic population.</p>","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 3","pages":"291-295"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145505759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large subfoveal pigment epithelial detachment causing macular hole formation: Surgical approach. 大的中央凹下色素上皮脱离引起黄斑孔形成:手术入路。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_184_24
Vikas Ambiya, Gaurav Kapoor, Vijay Kumar Sharma

Subfoveal pigment epithelial detachments (PEDs) have been reported to develop full-thickness macular hole (FTMH). The response to treatment has been varied in different reports, with most cases having persistent PED even after successful surgical closure of the macular hole. Here, we report an unusual case of nonneovascular age-related macular degeneration, having a large subfoveal serous PED, leading to the formation of a large FTMH, which showed complete flattening of the PED with a successful closure of the macular hole with the surgical approach.

有报道称,中央凹下色素上皮脱落(PEDs)可发展为全层黄斑孔(FTMH)。对治疗的反应在不同的报告中有所不同,大多数病例即使在成功的手术关闭黄斑孔后仍持续存在PED。在这里,我们报告了一个不寻常的非新生血管性年龄相关性黄斑变性病例,有一个大的中央凹下浆液性PED,导致形成一个大的FTMH,显示PED完全平坦,通过手术成功关闭黄斑孔。
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引用次数: 0
Awareness, knowledge, and attitude toward ocular prosthesis among undergraduate allied health sciences, medical and nursing students in Goa. 果阿邦医科和护理专业本科学生对眼假体的认知、知识和态度。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_79_24
Purva P Korgaonkar, Ugam P S Usgaonkar, Harshada N Narvekar

Background: For patients who have apparent disfigurement of the eye, ocular prostheses are an essential kind of treatment. Students from medical colleges can play a major role in sensitizing needy patients to the availability of prosthetic devices for the correction of eye disfiguration. To do this, they must be reasonably aware and knowledgeable about the availability, functioning and general aspects of ocular prosthetics. The purpose of the study was to assess the awareness, knowledge, and attitude regarding ocular prosthetics in students studying allied health sciences (AHS), medicine, and nursing.

Materials and methods: A cross-sectional descriptive study was carried out using a self-administered, closed-ended, structured questionnaire to gather information on awareness, knowledge and attitude towards ocular prosthetics from AHS, medical and nursing students of Goa.

Results: A total of 322 pupils took part in the study. The primary source of information included classroom lectures, workshops and conferences (46.0%), followed by internet resources and social media (33.5%). The knowledge and attitude differed significantly between AHS, medical, and nursing students. Overall, 3rd-year students had adequate knowledge scores (8.39 ± 2.4) compared to 2nd-year (5.71 ± 3.0) and 1st-year students (3.95 ± 3.4).

Conclusions: Students had deficient knowledge of certain aspects of ocular prosthesis, indicating a need for education in the subject. The study also highlights how students' knowledge and attitude can influence the future of prosthetic rehabilitation.

背景:对于有明显眼部畸形的患者,眼假体是一种必不可少的治疗方法。医学院的学生可以发挥重要作用,使有需要的病人对矫正眼睛畸形的假体装置的可用性敏感。要做到这一点,他们必须合理地了解和了解眼部假肢的可用性、功能和一般方面。本研究的目的是评估联合健康科学(AHS)、医学和护理专业学生对眼修复术的认知、知识和态度。材料和方法:采用自我管理的封闭式结构化问卷进行横断面描述性研究,收集果阿邦AHS、医学和护理专业学生对眼假体的认知、知识和态度信息。结果:共有322名学生参加了这项研究。信息的主要来源包括课堂讲座、研讨会和会议(46.0%),其次是互联网资源和社交媒体(33.5%)。AHS学生、医学生和护学生的知识和态度存在显著差异。总体而言,三年级学生的知识得分(8.39±2.4)高于二年级(5.71±3.0)和一年级(3.95±3.4)。结论:学生对眼假体的某些方面的知识不足,表明需要进行这方面的教育。研究也强调了学生的知识和态度如何影响假肢康复的未来。
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引用次数: 0
Lenticular injury due to inadvertent intravitreal injection. 由于玻璃体内不小心注射造成的晶状体损伤。
Q3 Medicine Pub Date : 2025-10-28 eCollection Date: 2025-09-01 DOI: 10.4103/ojo.ojo_394_24
Sonali Prataprao Lomte, Prajakta Paritekar
{"title":"Lenticular injury due to inadvertent intravitreal injection.","authors":"Sonali Prataprao Lomte, Prajakta Paritekar","doi":"10.4103/ojo.ojo_394_24","DOIUrl":"10.4103/ojo.ojo_394_24","url":null,"abstract":"","PeriodicalId":19461,"journal":{"name":"Oman Journal of Ophthalmology","volume":"18 3","pages":"412-413"},"PeriodicalIF":0.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145505905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Oman Journal of Ophthalmology
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