Oman Journal of Ophthalmology最新文献

Aim: The aim of this study was to compare the sedative and analgesic effects of ketorolac and diclofenac eye drops among patients with cataract surgery (CS) who received tetracaine.

Methods: This double-blind randomized clinical trial was conducted in 2022. Participants were the candidates for CS consecutively selected from Amirkabir hospital, Arak, Iran, and were assigned to an artificial tear group, a ketorolac group, and a diclofenac group through block randomization. Pain, sedation status, heart rate, blood pressure, and arterial oxygen saturation were assessed during and after surgery. Complications prevalence and intraoperative propofol use were also documented. Data were analyzed using the SPSS software (v. 20.0) at a significance level of <0.05.

Results: There were no significant differences among the study groups respecting participants' age, gender, body mass index, blood pressure, heart rate, arterial oxygen saturation, CS duration, and Aldrete score (P > 0.05). From 5 min after CS onward, the mean score of pain in the ketorolac group was significantly less than the other groups (P < 0.05). The mean score of sedation from recovery to 1 h after surgery in the artificial tear group was significantly more than the other groups, whereas the mean score of sedation 2 and 4 h after CS in the ketorolac group was significantly more than the other groups (P < 0.05). Propofol use in the artificial tear group was significantly more than in other groups (P = 0.001) and patient and surgeon satisfaction in this group was significantly less than in other groups (P < 0.05). The ketorolac and the diclofenac groups did not significantly differ from each other respecting surgeon and patient satisfaction and the prevalence of complications (P > 0.05).

Conclusion: Ketorolac eye drops are more effective than diclofenac eye drops in significantly reducing intraoperative pain among the candidates for CS with topical anesthesia. Therefore, ketorolac eye drops can be used with tetracaine eye drops in CS with topical anesthesia to produce greater perioperative analgesia and sedation.

Retinal vascular occlusions are rare in young people, and any occlusion warrants an extensive clinical evaluation to establish the etiology. Cardiac malformations are a source of embolism. We present a case of atrial septal defect (ASD) in a patient with type II Mayer-Rokitansky-Küster-Hauser syndrome, leading to unilateral branch retinal arterial occlusion (BRAO) in a young woman. A 21-year-old woman presented with sudden, painless, blurring of vision, and a superior visual field defect in her right eye. A fundus examination confirmed the BRAO diagnosis. Ocular and systemic evaluation revealed primary amenorrhea, ASD, ectopic kidneys, and pelvic cyst. Any vascular occlusion in a young patient must be thoroughly evaluated, including a detailed systemic history.

Aim: The aim of the study was to correlate the optic nerve dimensions at various locations on magnetic resonance imaging (MRI) with the visual acuity of children with cerebral visual impairment (CVI).

Materials and methods: A 1-year cross-sectional study was conducted in a tertiary care hospital involving 60 children aged 1 to 12 years diagnosed with CVI but without ocular pathologies. Visual acuity was evaluated using teller acuity cards (TACs). MRI of the brain and orbit was performed using three-dimensional high-resolution, volumetric heavily T2-weighted sequences to screen for brain pathologies and measure optic nerve dimensions at two locations. The correlation between visual acuity and optic nerve dimensions was analyzed. The Chi-square test was employed to assess significance using SPSS software.

Results: In our study, 64% (n = 38) of the participants were children under 3 years of age. The severity and characteristics of CVI influenced visual functioning at different ages. As children with CVI grew older and moved from Phase I to Phase III, the proportion with very low visual acuity significantly decreased from 85.2% in Phase I to 22.2% in Phase III and from 63.2% in the <3-year age group to 18.2% in more than 5-year age group. No direct correlation was found between optic nerve dimensions and visual acuity but optic disc changes such as optic disc pallor significantly correlated with low visual acuity.

Conclusion: Our findings suggest that there may not be a direct correlation between optic nerve dimensions and visual acuity in children with CVI. However, optic disc changes do correlate with visual acuity, but optic disc changes alone are not a criterion for assessing visual function. Additionally, our study highlights the significance of a combined assessment by a neuro- ophthalmologist and neuro-pedaitrician in children with CVI.

Purpose: The purpose of this study was to compare early visual outcomes, epithelial healing, and stromal haze between transepithelial photorefractive keratectomy (Trans-PRK) using smart pulse technology (SPT) with traditional Trans-PRK.

Methodology: This study is a retrospective, comparative study conducted at a private eye center in "Riyadh, Saudi Arabia," investigating myopic patients who underwent either Trans-PRK with SPT (study group) or traditional Trans-PRK (control group). The patients were assessed preoperatively and followed up at 1 week and 2 months postoperatively. The main outcomes included uncorrected distance visual acuity (UDVA), corneal haze, and corneal epithelial defect.

Results: This study included 501 eyes, of them, 222 eyes (44.3%) underwent Trans-PRK with SPT. The UDVA in the study group was significantly better 1 week postoperatively (P < 0.05). For the 2-month follow-up visits, there was no significant difference between the groups. Epithelium healing and stromal haze were comparable in the two groups without significant differences between them.

Conclusion: Transepithelial photorefractive keratectomy with SPT yielded better short-term visual outcomes than traditional Transepithelial photorefractive keratectomy.

Background: This study aims to evaluate the knowledge levels of chat generative pretrained transformer (ChatGPT), Bing, and Bard programs, which are three different artificial intelligence chatbots offered to the market free of charge by various manufacturers, regarding neuro-ophthalmological diseases, to examine their usability, and to investigate the existence of their superiority to each other.

Materials and methods: Forty questions related to neuro-ophthalmological diseases were obtained from the study questions' section of the American Academy and Ophthalmology 2022-2023 Basic and Clinical Science Course Neuro-ophthalmology Book. The questions were posed to the ChatGPT, Bing, and Bard artificial intelligence chatbots. The answers were evaluated as correct or incorrect. The statistical relationship between the correct and incorrect answer rates offered by the artificial intelligence programs was tested.

Results: The correct answer rates were given by the artificial intelligence programs to the questions asked: ChatGPT - 52.5%; Bing - 55%; and Bard - 65%. There was no statistically significant difference between the correct answer rates of the three artificial intelligence programs (P = 0.489, Pearson's Chi-square test).

Conclusion: Although information about neuro-ophthalmological diseases can be accessed quickly and accurately using up-to-date artificial intelligence programs, the answers given may not always be correct. Care should always be taken when evaluating the answers to the questions.

Objective: The objective of the study was to determine the incidence, patterns, and risk factors for the development of retinopathy of prematurity (ROP) in infants weighing >1500 g at birth.

Materials and methods: A retrospective analysis was done of the ROP screening records between April 2019 and March 2022. All the infants with birth weight >1500 g who underwent ROP screening were included. Data collected included demographic details, details of the risk factors (respiratory distress syndrome [RDS], hypoxia, anemia, septicemia, patent ductus arteriosus, congenital heart disease [CHD], i.e., atrial septal defects or ventricular septal defects, and multiple gestations), and ocular examination findings. Statistical analyses included calculation of mean, range, Chi-square test, and bivariate logistic regression for associations of risk factors with ROP.

Results: ROP was noted in 16.6% of the 336 eyes of 168 infants. The mean birth weight and mean gestational age (GA) of the infants were 1850 ± 33 g and 33.33 weeks ± 1.71 weeks, respectively. Eighteen eyes (32.1%) had Stage I, 17 eyes (30.35%) had Stage II, and 11 eyes (19.64%) had Stage III ROP in Zone II. Aggressive ROP was seen in 8 eyes (14.28%) and stage 5 ROP in two eyes (0.59%). Male gender, GA, CHD, and RDS showed a statistically significant association with the development of ROP in these infants.

Conclusion: ROP was seen in 16.66% of our subjects. Treatment was required in 6.25% of infants. Risk factors for the development of ROP were low gestational age, male gender, the presence of RDS, and congenital heart disease.