Yi Su, Guoguang Rong, Sumin Bian, Pengbo Wang, Lingfei Li, Yun-Hsuan Chen, Chao Huang, Hongyong Zhang, Mohamad Sawan
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Dark-Field Resonance Rayleigh Scattering Biosensor to Monitor Small Molecules and Determine the Secretory Ability of Single Neuron (Adv. Mater. Technol. 15/2024)
Resonance Rayleigh Scattering
Accurate monitoring of neurotransmitters and precise characterization of the secretory ability of neurons are essential for effective treatment of neurological diseases. In article number 2301701, Mohamad Sawan and co-workers discover that the binding of small neurotransmitters to aptamers induces a conformational change that alters the effective radius of Au nanoclusters-aptamer complexes. This change can be detected in the resonance Rayleigh scattering intensity.
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