{"title":"通过纳米孔电穿孔技术进行 DNA 增强型细胞内蛋白质输送","authors":"Matthew Lee Manion , Albert Tianxiang Liu","doi":"10.1016/j.matt.2024.06.009","DOIUrl":null,"url":null,"abstract":"<div><p>Core to the prospects of cellular engineering are methods to load cells with a range of exogenous cargo that maintain cargo faculties upon delivery. An interdisciplinary team at Northwestern University presents a localized version of electroporation, using nanopore membranes, that can deliver large proteins efficiently with preserved functionality.</p></div>","PeriodicalId":388,"journal":{"name":"Matter","volume":"7 8","pages":"Pages 2727-2729"},"PeriodicalIF":17.5000,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"DNA augmented intracellular protein delivery via nanopore electroporation\",\"authors\":\"Matthew Lee Manion , Albert Tianxiang Liu\",\"doi\":\"10.1016/j.matt.2024.06.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Core to the prospects of cellular engineering are methods to load cells with a range of exogenous cargo that maintain cargo faculties upon delivery. An interdisciplinary team at Northwestern University presents a localized version of electroporation, using nanopore membranes, that can deliver large proteins efficiently with preserved functionality.</p></div>\",\"PeriodicalId\":388,\"journal\":{\"name\":\"Matter\",\"volume\":\"7 8\",\"pages\":\"Pages 2727-2729\"},\"PeriodicalIF\":17.5000,\"publicationDate\":\"2024-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Matter\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S259023852400328X\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Matter","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S259023852400328X","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
DNA augmented intracellular protein delivery via nanopore electroporation
Core to the prospects of cellular engineering are methods to load cells with a range of exogenous cargo that maintain cargo faculties upon delivery. An interdisciplinary team at Northwestern University presents a localized version of electroporation, using nanopore membranes, that can deliver large proteins efficiently with preserved functionality.
期刊介绍：
Matter, a monthly journal affiliated with Cell, spans the broad field of materials science from nano to macro levels,covering fundamentals to applications. Embracing groundbreaking technologies,it includes full-length research articles,reviews, perspectives,previews, opinions, personnel stories, and general editorial content.
Matter aims to be the primary resource for researchers in academia and industry, inspiring the next generation of materials scientists.
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