Pub Date : 2025-02-18DOI: 10.1016/j.matt.2025.102004
Fangchao Gu, Wu Wang, Hong Meng, Yiwen Liu, Lei Zhuang, Hulei Yu, Yanhui Chu
Electromagnetic pollution has emerged as a severe global issue due to the widespread use of wireless communication, which strongly requires high-performance electromagnetic wave absorbents. Here, we realize exceptional electromagnetic wave absorption performance with an effective absorption bandwidth of 7.2 GHz at an ultralow thickness of 1.5 mm in high-entropy diborides through a lattice distortion engineering strategy. Particularly, we rationally tailor the lattice distortion of high-entropy diborides by manipulating constituent metal elements, and the resultant metal vacancies and chemical nanoclusters are verified to result in enriched electromagnetic wave absorption mechanisms, including (1) metal vacancy-induced dipole polarization loss, (2) metal vacancy-induced conduction loss, and (3) chemical nanocluster-induced interfacial polarization loss. Our work provides a simple and universal approach for effectively enhancing the electromagnetic wave absorption performance of ceramic absorbents.
{"title":"Lattice distortion boosted exceptional electromagnetic wave absorption in high-entropy diborides","authors":"Fangchao Gu, Wu Wang, Hong Meng, Yiwen Liu, Lei Zhuang, Hulei Yu, Yanhui Chu","doi":"10.1016/j.matt.2025.102004","DOIUrl":"https://doi.org/10.1016/j.matt.2025.102004","url":null,"abstract":"Electromagnetic pollution has emerged as a severe global issue due to the widespread use of wireless communication, which strongly requires high-performance electromagnetic wave absorbents. Here, we realize exceptional electromagnetic wave absorption performance with an effective absorption bandwidth of 7.2 GHz at an ultralow thickness of 1.5 mm in high-entropy diborides through a lattice distortion engineering strategy. Particularly, we rationally tailor the lattice distortion of high-entropy diborides by manipulating constituent metal elements, and the resultant metal vacancies and chemical nanoclusters are verified to result in enriched electromagnetic wave absorption mechanisms, including (1) metal vacancy-induced dipole polarization loss, (2) metal vacancy-induced conduction loss, and (3) chemical nanocluster-induced interfacial polarization loss. Our work provides a simple and universal approach for effectively enhancing the electromagnetic wave absorption performance of ceramic absorbents.","PeriodicalId":388,"journal":{"name":"Matter","volume":"13 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143435562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-17DOI: 10.1016/j.matt.2025.101990
Justin P. Chen, Thomas W. Colburn, Juliet Risner-Jamtgaard, Arturas Vailionis, Andrew Barnum, Margarita Golding, Abigail Carbone, Austin C. Flick, Reinhold H. Dauskardt
A [6,6]-phenyl C61 butyric acid methyl ester (PCBM) and bathocuproine (BCP) electron transport layer (ETL) is spray deposited in open air directly on top of a perovskite at linear speeds of 9 m/min. The PCBM precursor ink contains a binary mixture of 1:1 chlorobenzene:chloroform, which optimizes spray wettability on the perovskite surface and allows quick solvent evaporation. A near-infrared heating module additionally provides a flash cure (<5 s) for the formation of smooth, large-area PCBM films (∼20 cm2). A BCP solution in isopropanol is subsequently sprayed to form an ultrathin (<5 nm) film and characterized with a suite of high-resolution metrologies. The spray-deposition processing and near-infrared treatment do not damage the underlying perovskite. Inverted architecture devices containing the sprayed ETL achieve a champion efficiency of 20.3% and demonstrate stable performance without additional interlayers or surface treatments. The technoeconomic cost of the open-air spray process is compared against traditional vacuum-based evaporation, resulting in a decrease in manufacturing costs by 26%.
{"title":"Open-air spray deposition of PCBM/BCP electron transport layer for inverted perovskite solar cells","authors":"Justin P. Chen, Thomas W. Colburn, Juliet Risner-Jamtgaard, Arturas Vailionis, Andrew Barnum, Margarita Golding, Abigail Carbone, Austin C. Flick, Reinhold H. Dauskardt","doi":"10.1016/j.matt.2025.101990","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101990","url":null,"abstract":"A [6,6]-phenyl C<sub>61</sub> butyric acid methyl ester (PCBM) and bathocuproine (BCP) electron transport layer (ETL) is spray deposited in open air directly on top of a perovskite at linear speeds of 9 m/min. The PCBM precursor ink contains a binary mixture of 1:1 chlorobenzene:chloroform, which optimizes spray wettability on the perovskite surface and allows quick solvent evaporation. A near-infrared heating module additionally provides a flash cure (<5 s) for the formation of smooth, large-area PCBM films (∼20 cm<sup>2</sup>). A BCP solution in isopropanol is subsequently sprayed to form an ultrathin (<5 nm) film and characterized with a suite of high-resolution metrologies. The spray-deposition processing and near-infrared treatment do not damage the underlying perovskite. Inverted architecture devices containing the sprayed ETL achieve a champion efficiency of 20.3% and demonstrate stable performance without additional interlayers or surface treatments. The technoeconomic cost of the open-air spray process is compared against traditional vacuum-based evaporation, resulting in a decrease in manufacturing costs by 26%.","PeriodicalId":388,"journal":{"name":"Matter","volume":"35 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natural plants provide a wealth of valuable materials for healthcare, with much of their potential often overlooked in what is commonly considered waste. This study focuses on the Malva nut tree (Sterculia lychnophora Hance), whose fruit, Pangdahai (PDH), has long been used in traditional Chinese medicine. By investigating the swelling behavior of PDH husk, we efficiently extracted its polysaccharides without harsh chemicals. Using micro-compression, we developed a viscoelastic hydrogel, and through electrostatic crosslinking with chitosan, we further enhanced its mechanical properties. The hydrogel exhibited biocompatibility and accelerated wound healing by promoting keratinocyte migration. Additionally, it outperformed commercial patches as a skin-attached interfacial material for electrocardiography (ECG), demonstrating superior signal-to-noise ratios. Integrated into a 16-channel mesh electronic device, the hydrogel provided stable performance for in vivo epicardial ECG recording on a beating heart. This research highlights the potential of rigid polysaccharide waste, presenting a sustainable approach to converting plant waste into valuable healthcare materials.
{"title":"Sustainable conversion of husk into viscoelastic hydrogels for value-added biomedical applications","authors":"Changxu Sun, Jiping Yue, Pengju Li, Wen Li, Jingcheng Ma, Chuanwang Yang, Saehyun Kim, Bozhi Tian","doi":"10.1016/j.matt.2025.102002","DOIUrl":"https://doi.org/10.1016/j.matt.2025.102002","url":null,"abstract":"Natural plants provide a wealth of valuable materials for healthcare, with much of their potential often overlooked in what is commonly considered waste. This study focuses on the Malva nut tree (<em>Sterculia lychnophora</em> Hance), whose fruit, <em>Pangdahai</em> (PDH), has long been used in traditional Chinese medicine. By investigating the swelling behavior of PDH husk, we efficiently extracted its polysaccharides without harsh chemicals. Using micro-compression, we developed a viscoelastic hydrogel, and through electrostatic crosslinking with chitosan, we further enhanced its mechanical properties. The hydrogel exhibited biocompatibility and accelerated wound healing by promoting keratinocyte migration. Additionally, it outperformed commercial patches as a skin-attached interfacial material for electrocardiography (ECG), demonstrating superior signal-to-noise ratios. Integrated into a 16-channel mesh electronic device, the hydrogel provided stable performance for <em>in vivo</em> epicardial ECG recording on a beating heart. This research highlights the potential of rigid polysaccharide waste, presenting a sustainable approach to converting plant waste into valuable healthcare materials.","PeriodicalId":388,"journal":{"name":"Matter","volume":"47 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flexible optical wireless communication is significant for major strategic needs due to its safety, portability, and precision. As a core component in optical communication systems, photodetectors (PDs) are plagued by stringent requirements, including high detectivity, stability, and flexibility. Herein, an optical wireless communication system based on flexible two-dimensional (2D) Ruddlesden-Popper (RP) perovskite PDs is presented. The thickness-optimized PD with outstanding thermal stability and flexibility has a high responsivity over the visible light range with two peaks at 488 and 532 nm. Based on these advancements, a multiplexing encrypted communication system is presented by exploiting the 488 and 532 nm light as independent information transmission channels to improve information security. Moreover, the flexible PD is integrated into the integrated circuit to simulate an optical wireless communication system for visible light positioning and bidirectional information transmission, which realizes the real-time positioning of the vehicle and the real-time presentation of the user interface.
{"title":"High-performance 2D perovskite-based flexible photodetectors for optical communication and information encryption","authors":"Kaijia Feng, Ying Li, Yancheng Chen, Zhongming Wei, Guozhen Shen","doi":"10.1016/j.matt.2025.101998","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101998","url":null,"abstract":"Flexible optical wireless communication is significant for major strategic needs due to its safety, portability, and precision. As a core component in optical communication systems, photodetectors (PDs) are plagued by stringent requirements, including high detectivity, stability, and flexibility. Herein, an optical wireless communication system based on flexible two-dimensional (2D) Ruddlesden-Popper (RP) perovskite PDs is presented. The thickness-optimized PD with outstanding thermal stability and flexibility has a high responsivity over the visible light range with two peaks at 488 and 532 nm. Based on these advancements, a multiplexing encrypted communication system is presented by exploiting the 488 and 532 nm light as independent information transmission channels to improve information security. Moreover, the flexible PD is integrated into the integrated circuit to simulate an optical wireless communication system for visible light positioning and bidirectional information transmission, which realizes the real-time positioning of the vehicle and the real-time presentation of the user interface.","PeriodicalId":388,"journal":{"name":"Matter","volume":"23 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LiMXCl4, a recently discovered lithium superionic conductor, achieves Li conductivity up to 12.4 mS/cm at room temperature. Notably, LiNbOCl4 features flexible, rotating polyhedra, potentially explaining its high ionic conductivity. However, the generalizability of these findings across different chemistries and the direct link between polyhedra rotations and Li-ion mobility remain unclear. In this study, we explore various M-cation and X-anion substitutions in the LiMXCl4 system, identifying fluoro-chlorides as promising for enhancing electrochemical stability while maintaining high ionic conductivity. Meyer-Neldel analysis on ab initio simulations reveals that LiMXCl4 outperforms existing halide conductors, with projected conductivities of 10–100 mS/cm. Our probabilistic analysis of lithium-ion hops and small-angle tilting events reveals a “soft cradle effect,” where weakly bound M-octahedra tilt in conjunction with Li-ion hops, optimizing the energy landscape. This work provides fundamental insights into the factors driving high ionic conductivity in non-close-packed oxyhalide systems and suggests exciting directions for further improving these materials.
{"title":"Exploring the soft cradle effect and ionic transport mechanisms in the LiMXCl4 superionic conductor family","authors":"KyuJung Jun, Grace Wei, Xiaochen Yang, Yu Chen, Gerbrand Ceder","doi":"10.1016/j.matt.2025.102001","DOIUrl":"https://doi.org/10.1016/j.matt.2025.102001","url":null,"abstract":"LiMXCl<sub>4</sub>, a recently discovered lithium superionic conductor, achieves Li conductivity up to 12.4 mS/cm at room temperature. Notably, LiNbOCl<sub>4</sub> features flexible, rotating polyhedra, potentially explaining its high ionic conductivity. However, the generalizability of these findings across different chemistries and the direct link between polyhedra rotations and Li-ion mobility remain unclear. In this study, we explore various M-cation and X-anion substitutions in the LiMXCl<sub>4</sub> system, identifying fluoro-chlorides as promising for enhancing electrochemical stability while maintaining high ionic conductivity. Meyer-Neldel analysis on <em>ab initio</em> simulations reveals that LiMXCl<sub>4</sub> outperforms existing halide conductors, with projected conductivities of 10–100 mS/cm. Our probabilistic analysis of lithium-ion hops and small-angle tilting events reveals a “soft cradle effect,” where weakly bound M-octahedra tilt in conjunction with Li-ion hops, optimizing the energy landscape. This work provides fundamental insights into the factors driving high ionic conductivity in non-close-packed oxyhalide systems and suggests exciting directions for further improving these materials.","PeriodicalId":388,"journal":{"name":"Matter","volume":"30 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1016/j.matt.2025.101999
Weicheng Kong, Yuling Lu, Ximin Yuan, Meng Zhu, Qilin Wu, Ke Yao, Tao Fu, Yong He
The traditional three-dimensional (3D) printing technique requires high energy to break and re-form the metal bonds. Here, we present the latest discovery of the metal polymerization reaction at room temperature with the non-breaking and re-forming bond method, which is similar to the polymerization phenomenon of the AB reaction. The A and B in the AB reaction represent the eutectic gallium–indium liquid metal and transition metal alloy, respectively, and their same atomic structures generate the aggregation to form the new alloy phases, showing that the printed Ga–In–Cu alloy has superior mechanical properties. Moreover, the AB reaction model is established to elucidate the reaction mechanism between the A and the B, which exhibits excellent printable performance. This polymerization reaction of the alloys pioneers a novel approach to the formation of alloys, which has become one of the important trends in future manufacturing industries.
{"title":"3D printing of alloys with AB reaction at room temperature","authors":"Weicheng Kong, Yuling Lu, Ximin Yuan, Meng Zhu, Qilin Wu, Ke Yao, Tao Fu, Yong He","doi":"10.1016/j.matt.2025.101999","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101999","url":null,"abstract":"The traditional three-dimensional (3D) printing technique requires high energy to break and re-form the metal bonds. Here, we present the latest discovery of the metal polymerization reaction at room temperature with the non-breaking and re-forming bond method, which is similar to the polymerization phenomenon of the AB reaction. The A and B in the AB reaction represent the eutectic gallium–indium liquid metal and transition metal alloy, respectively, and their same atomic structures generate the aggregation to form the new alloy phases, showing that the printed Ga–In–Cu alloy has superior mechanical properties. Moreover, the AB reaction model is established to elucidate the reaction mechanism between the A and the B, which exhibits excellent printable performance. This polymerization reaction of the alloys pioneers a novel approach to the formation of alloys, which has become one of the important trends in future manufacturing industries.","PeriodicalId":388,"journal":{"name":"Matter","volume":"2 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1016/j.matt.2025.102000
Bongki Shin, Bo Ni, Chee-Tat Toh, Doug Steinbach, Zhenze Yang, Lucas M. Sassi, Qing Ai, Kangdi Niu, Junhao Lin, Kazu Suenaga, Yimo Han, Markus J. Buehler, Barbaros Özyilmaz, Jun Lou
Two-dimensional (2D) materials have immense potential to advance flexible electronics, yet they are limited by low fracture toughness. This study addresses the intrinsic toughening of monolayer amorphous carbon (MAC), a 2D nanocomposite, to overcome this challenge. By incorporating both amorphous and nanocrystalline phases, MAC significantly enhances energy absorption during fracture propagation, as evidenced by crack blunting, deflecting, and bridging. Using in situ tensile tests under a scanning electron microscope, our results indicate an 8-fold increase in the energy release rate compared to monolayer graphene, along with improved fracture strain and crack stability. Molecular dynamics simulations demonstrate the impact of phase composition on fracture energy. Our results present a scalable toughening strategy for 2D materials, potentially broadening their applications in fields requiring robust fracture resistance.
{"title":"Intrinsic toughening in monolayer amorphous carbon nanocomposites","authors":"Bongki Shin, Bo Ni, Chee-Tat Toh, Doug Steinbach, Zhenze Yang, Lucas M. Sassi, Qing Ai, Kangdi Niu, Junhao Lin, Kazu Suenaga, Yimo Han, Markus J. Buehler, Barbaros Özyilmaz, Jun Lou","doi":"10.1016/j.matt.2025.102000","DOIUrl":"https://doi.org/10.1016/j.matt.2025.102000","url":null,"abstract":"Two-dimensional (2D) materials have immense potential to advance flexible electronics, yet they are limited by low fracture toughness. This study addresses the intrinsic toughening of monolayer amorphous carbon (MAC), a 2D nanocomposite, to overcome this challenge. By incorporating both amorphous and nanocrystalline phases, MAC significantly enhances energy absorption during fracture propagation, as evidenced by crack blunting, deflecting, and bridging. Using <em>in situ</em> tensile tests under a scanning electron microscope, our results indicate an 8-fold increase in the energy release rate compared to monolayer graphene, along with improved fracture strain and crack stability. Molecular dynamics simulations demonstrate the impact of phase composition on fracture energy. Our results present a scalable toughening strategy for 2D materials, potentially broadening their applications in fields requiring robust fracture resistance.","PeriodicalId":388,"journal":{"name":"Matter","volume":"4 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-12DOI: 10.1016/j.matt.2025.101989
Shang Chi, Yaping Li, Tingting Ye, Jiawei Kang, Zhihui Xiang, Xiaoqing Kuang, Chenggang Yi, Yiying Qi, Wei Wang
This work developed a de novo sonosensitizer based on carnosine_zinc piezoelectric metal-organic frameworks (PMOFs) that possesses a prominent reactive oxygen species (ROS)-generating function, biocompatibility, and degradability. Further, the PMOF was modified by a carbon monoxide (CO) donor through a metal complexation reaction to result in a multifunctional CO-PMOF to launch CO/ROS-mediated antimicrobial under ultrasound (US). However, the heat generated during sonodynamic therapy (SDT) may harm wounds. To minimize the waste energy and promote wound self-closure rate, a strong adhesive, and rapid thermal-responsive contraction (52.4%, 4 min), injectable hydrogel was designed to load CO-PMOF. The resulting ultrasonic triple-responsive hydrogel (UTGel) exhibits an effective biofilm destruction capability based on a CO/ROS-mediated antimicrobial therapy. After administration in an infected diabetic skin wound model in mice, UTGel can efficiently harvest the thermal energy by the CO-PMOF under US to trigger a centripetal shrinkage of the hydrogel and guide rapid wound self-closure.
{"title":"Energy reconversion of ultrasound on a piezoelectric hydrogel promotes ROS/CO generation and wound self-closure for infected chronic wound healing","authors":"Shang Chi, Yaping Li, Tingting Ye, Jiawei Kang, Zhihui Xiang, Xiaoqing Kuang, Chenggang Yi, Yiying Qi, Wei Wang","doi":"10.1016/j.matt.2025.101989","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101989","url":null,"abstract":"This work developed a <em>de novo</em> sonosensitizer based on carnosine_zinc piezoelectric metal-organic frameworks (PMOFs) that possesses a prominent reactive oxygen species (ROS)-generating function, biocompatibility, and degradability. Further, the PMOF was modified by a carbon monoxide (CO) donor through a metal complexation reaction to result in a multifunctional CO-PMOF to launch CO/ROS-mediated antimicrobial under ultrasound (US). However, the heat generated during sonodynamic therapy (SDT) may harm wounds. To minimize the waste energy and promote wound self-closure rate, a strong adhesive, and rapid thermal-responsive contraction (52.4%, 4 min), injectable hydrogel was designed to load CO-PMOF. The resulting ultrasonic triple-responsive hydrogel (UTGel) exhibits an effective biofilm destruction capability based on a CO/ROS-mediated antimicrobial therapy. After administration in an infected diabetic skin wound model in mice, UTGel can efficiently harvest the thermal energy by the CO-PMOF under US to trigger a centripetal shrinkage of the hydrogel and guide rapid wound self-closure.","PeriodicalId":388,"journal":{"name":"Matter","volume":"129 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-11DOI: 10.1016/j.matt.2025.101997
Yang An, Jihua Liu, Xiaoyu Cheng, Zhenzhen Dong, Yubiao Huang, Ge Sun, Jiarui Du, Guangjun Nie, Yinlong Zhang
Antiplatelet agents (APAs) are crucial for the clinical prevention and treatment of thrombotic diseases, but their long-term use has serious bleeding risk. In emergency situations, it is essential to rapidly reverse the effect of APAs and restore the hemostatic function of platelets. However, there are currently no specific antiplatelet reversal agents approved for clinical use. Here, we describe a click chemistry-functionalized gold nanoplatform for the reversal of APAs. The gold nanoparticles (AuNPs), modified with dibenzocyclooctyne or maleimide on their surface, are able to neutralize the antiplatelet activity of azido-modified ticagrelor and clopidogrel, respectively. The in vitro platelet aggregation assays and in vivo tail bleeding or liver injury experiments validate the effectiveness of the gold nanoplatform. In summary, our study introduces a gold nanoplatform that can be easily prepared through a simple method and has great potential to be used for the functional reversal of various APAs.
{"title":"Click chemistry-functionalized gold nanoparticles for the functional reversal of P2Y12 inhibitors","authors":"Yang An, Jihua Liu, Xiaoyu Cheng, Zhenzhen Dong, Yubiao Huang, Ge Sun, Jiarui Du, Guangjun Nie, Yinlong Zhang","doi":"10.1016/j.matt.2025.101997","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101997","url":null,"abstract":"Antiplatelet agents (APAs) are crucial for the clinical prevention and treatment of thrombotic diseases, but their long-term use has serious bleeding risk. In emergency situations, it is essential to rapidly reverse the effect of APAs and restore the hemostatic function of platelets. However, there are currently no specific antiplatelet reversal agents approved for clinical use. Here, we describe a click chemistry-functionalized gold nanoplatform for the reversal of APAs. The gold nanoparticles (AuNPs), modified with dibenzocyclooctyne or maleimide on their surface, are able to neutralize the antiplatelet activity of azido-modified ticagrelor and clopidogrel, respectively. The <em>in vitro</em> platelet aggregation assays and <em>in vivo</em> tail bleeding or liver injury experiments validate the effectiveness of the gold nanoplatform. In summary, our study introduces a gold nanoplatform that can be easily prepared through a simple method and has great potential to be used for the functional reversal of various APAs.","PeriodicalId":388,"journal":{"name":"Matter","volume":"47 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143385230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-10DOI: 10.1016/j.matt.2025.101988
Weiyao Zhao, Yao Zhang, Yuefeng Yin, Kaijian Xing, Shengqiang Zhou, Abdulhakim Bake, Golrokh Akhgar, David Cortie, Lei Chen, Xiaolin Wang, Kirrily C. Rule, Nikhil V. Medkehar, Simon Granville, Julie Karel
In amorphous materials, long-range translational order breaks down, and k is no longer a good quantum number; however, some of the phenomena, for instance ferromagnetic interactions and a mechanism similar to the Berry curvature, can be preserved. Here, we demonstrate a giant Berry-curvature-induced anomalous Hall effect and anomalous Hall angle in amorphous Co2MnGa (a-CMG) thin films. Remarkably, the effect presents the same magnitude as high-quality crystalline CMG with the L21 structure. The elastic neutron scattering peak in a-CMG is centered close to the crystalline phase, indicating that the amorphous material presents similar local atomic environments and magnetic interactions. First-principles density functional theory calculations further show that the anomalous Hall conductivity arises only when the local environments in the amorphous structure are similar to the L21 phase. Our work strongly points to the application of low-cost, industry-compatible, and thermally stable amorphous topological materials in emerging electronic and spintronic applications.
{"title":"Giant berry curvature in amorphous ferromagnet Co2MnGa","authors":"Weiyao Zhao, Yao Zhang, Yuefeng Yin, Kaijian Xing, Shengqiang Zhou, Abdulhakim Bake, Golrokh Akhgar, David Cortie, Lei Chen, Xiaolin Wang, Kirrily C. Rule, Nikhil V. Medkehar, Simon Granville, Julie Karel","doi":"10.1016/j.matt.2025.101988","DOIUrl":"https://doi.org/10.1016/j.matt.2025.101988","url":null,"abstract":"In amorphous materials, long-range translational order breaks down, and <em>k</em> is no longer a good quantum number; however, some of the phenomena, for instance ferromagnetic interactions and a mechanism similar to the Berry curvature, can be preserved. Here, we demonstrate a giant Berry-curvature-induced anomalous Hall effect and anomalous Hall angle in amorphous Co<sub>2</sub>MnGa (a-CMG) thin films. Remarkably, the effect presents the same magnitude as high-quality crystalline CMG with the L2<sub>1</sub> structure. The elastic neutron scattering peak in a-CMG is centered close to the crystalline phase, indicating that the amorphous material presents similar local atomic environments and magnetic interactions. First-principles density functional theory calculations further show that the anomalous Hall conductivity arises only when the local environments in the amorphous structure are similar to the L2<sub>1</sub> phase. Our work strongly points to the application of low-cost, industry-compatible, and thermally stable amorphous topological materials in emerging electronic and spintronic applications.","PeriodicalId":388,"journal":{"name":"Matter","volume":"51 1","pages":""},"PeriodicalIF":18.9,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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