{"title":"MCI 患者口语表达中言语和手势功能的异质性","authors":"","doi":"10.1016/j.jneuroling.2024.101227","DOIUrl":null,"url":null,"abstract":"<div><h3>Context</h3><p>Previous research has identified a homogeneous language behavior among women speakers with a progressive mild cognitive impairment (MCI). These speakers primarily utilize verbal and non-verbal pragmatic markers with interactive functions to maintain communication with the interlocutor, and this function significantly increases in time. However, the speakers have observed variations, prompting the development of an individualized analysis of the participants' discursive productions considering neurolinguistic models.</p></div><div><h3>Methods</h3><p>A multimodal and individualized analysis was conducted on five women over 75, diagnosed with progressive MCI, using longitudinal and natural language corpora. The data were processed using transcription tools (i.e., verbal discourse) and annotation tools (i.e., gestures), then subjected to Principal Component Analyses due to the diverse data set and discursive modalities to analyze for each individual.</p></div><div><h3>Results & conclusion</h3><p>The results reveal variations, even specialization, in verbal and gestural pragmatic markers based on cognitive and empathic profiles, as well as certain resilience factors among study participants. Three behavioral patterns emerge among the profiles of amnestic MCI with standard progression, multidomain MCI profiles, and MCI profiles occurring at a very advanced age in the context of good cognitive reserve. These findings encourage further research to characterize MCI as a dynamic and variable diagnostic entity from one individual to another. Additionally, corpus analysis could enable clinicians to assess the discourse of individuals with MCI for diagnostic purposes and evaluate treatments' effectiveness, especially speech therapy.</p></div>","PeriodicalId":50118,"journal":{"name":"Journal of Neurolinguistics","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Heterogeneity of verbal and gestural functions in spoken discourse with MCI\",\"authors\":\"\",\"doi\":\"10.1016/j.jneuroling.2024.101227\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Context</h3><p>Previous research has identified a homogeneous language behavior among women speakers with a progressive mild cognitive impairment (MCI). These speakers primarily utilize verbal and non-verbal pragmatic markers with interactive functions to maintain communication with the interlocutor, and this function significantly increases in time. However, the speakers have observed variations, prompting the development of an individualized analysis of the participants' discursive productions considering neurolinguistic models.</p></div><div><h3>Methods</h3><p>A multimodal and individualized analysis was conducted on five women over 75, diagnosed with progressive MCI, using longitudinal and natural language corpora. The data were processed using transcription tools (i.e., verbal discourse) and annotation tools (i.e., gestures), then subjected to Principal Component Analyses due to the diverse data set and discursive modalities to analyze for each individual.</p></div><div><h3>Results & conclusion</h3><p>The results reveal variations, even specialization, in verbal and gestural pragmatic markers based on cognitive and empathic profiles, as well as certain resilience factors among study participants. Three behavioral patterns emerge among the profiles of amnestic MCI with standard progression, multidomain MCI profiles, and MCI profiles occurring at a very advanced age in the context of good cognitive reserve. These findings encourage further research to characterize MCI as a dynamic and variable diagnostic entity from one individual to another. Additionally, corpus analysis could enable clinicians to assess the discourse of individuals with MCI for diagnostic purposes and evaluate treatments' effectiveness, especially speech therapy.</p></div>\",\"PeriodicalId\":50118,\"journal\":{\"name\":\"Journal of Neurolinguistics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-08-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurolinguistics\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S091160442400037X\",\"RegionNum\":3,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"LINGUISTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurolinguistics","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S091160442400037X","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"LINGUISTICS","Score":null,"Total":0}
Heterogeneity of verbal and gestural functions in spoken discourse with MCI
Context
Previous research has identified a homogeneous language behavior among women speakers with a progressive mild cognitive impairment (MCI). These speakers primarily utilize verbal and non-verbal pragmatic markers with interactive functions to maintain communication with the interlocutor, and this function significantly increases in time. However, the speakers have observed variations, prompting the development of an individualized analysis of the participants' discursive productions considering neurolinguistic models.
Methods
A multimodal and individualized analysis was conducted on five women over 75, diagnosed with progressive MCI, using longitudinal and natural language corpora. The data were processed using transcription tools (i.e., verbal discourse) and annotation tools (i.e., gestures), then subjected to Principal Component Analyses due to the diverse data set and discursive modalities to analyze for each individual.
Results & conclusion
The results reveal variations, even specialization, in verbal and gestural pragmatic markers based on cognitive and empathic profiles, as well as certain resilience factors among study participants. Three behavioral patterns emerge among the profiles of amnestic MCI with standard progression, multidomain MCI profiles, and MCI profiles occurring at a very advanced age in the context of good cognitive reserve. These findings encourage further research to characterize MCI as a dynamic and variable diagnostic entity from one individual to another. Additionally, corpus analysis could enable clinicians to assess the discourse of individuals with MCI for diagnostic purposes and evaluate treatments' effectiveness, especially speech therapy.
期刊介绍:
The Journal of Neurolinguistics is an international forum for the integration of the neurosciences and language sciences. JNL provides for rapid publication of novel, peer-reviewed research into the interaction between language, communication and brain processes. The focus is on rigorous studies of an empirical or theoretical nature and which make an original contribution to our knowledge about the involvement of the nervous system in communication and its breakdowns. Contributions from neurology, communication disorders, linguistics, neuropsychology and cognitive science in general are welcome. Published articles will typically address issues relating some aspect of language or speech function to its neurological substrates with clear theoretical import. Interdisciplinary work on any aspect of the biological foundations of language and its disorders resulting from brain damage is encouraged. Studies of normal subjects, with clear reference to brain functions, are appropriate. Group-studies on well defined samples and case studies with well documented lesion or nervous system dysfunction are acceptable. The journal is open to empirical reports and review articles. Special issues on aspects of the relation between language and the structure and function of the nervous system are also welcome.