股骨内侧髁OCD(骨软骨炎):影像学检查和关节镜检查之间的相关性。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-13 DOI:10.1007/s00256-024-04749-6
Jie C Nguyen, Vandan Patel, Liya Gendler, Donna G Blankenbaker, Kevin G Shea, Eric J Wall, James L Carey, Carl W Nissen, Diego Jaramillo, Theodore J Ganley
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引用次数: 0

摘要

骨软骨炎(Osteochondritis dissecans,OCD)是一种以骨软骨交界处为中心的病理状态,可能导致不稳定的软骨下碎片(后代)、上覆软骨的破坏,并可能与下层母骨分离。这是导致儿童和青少年慢性膝关节疼痛的原因之一。目前有关 OCD 病变的文献主要集中在股骨内侧髁 (MFC),但术语的使用并不一致,尤其是在区分骨骼未成熟和成熟患者的 OCD 病变时,造成了影像学检查、治疗和长期预后方面的不确定性。本文回顾了MFC OCD病变的病理生理学,强调了未成熟股骨髁次生生长板软骨内骨化的作用、影像学检查的基本原理以及可区分稳定病变、不稳定病变和生理学变异的关键影像学发现。本概述还以病例为基础,介绍了影像学与 ROCK(膝关节骨软骨炎研究)关节镜分类的相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Medial femoral condyle OCD (osteochondritis dissecans): correlation between imaging and arthroscopy.

Osteochondritis dissecans (OCD) describes a pathologic condition centered at the osteochondral junction that may result in an unstable subchondral fragment (progeny), disruption of the overlying cartilage, which may separate from the underlying parent bone. It is one of the causes of chronic knee pain in children and young adults. The current literature on OCD lesions focuses primarily on the medial femoral condyle (MFC), but inconsistent use of terminology, particularly in the distinction of OCD lesions between skeletally immature and mature patients has created uncertainty regarding imaging workup, treatment, and long-term prognosis. This article reviews the pathophysiology of MFC OCD lesions, highlighting the role of endochondral ossification at the secondary growth plate of the immature femoral condyles, the rationale behind the imaging work-up, and key imaging findings that can distinguish between stable lesions, unstable lesions, and physiologic variants. This overview also provides a case-based review to introduce imaging correlates with the ROCK (Research in Osteochondritis of the Knee) arthroscopic classification.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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