[人类呼吸道合胞病毒检测方法研究进展]。

N Wang, H Li, J J Song, J H Song, Y Zhang
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引用次数: 0

摘要

人类呼吸道合胞病毒(HRSV)可感染所有年龄段的人,五岁以下儿童、老年人和免疫力低下者是主要的高危人群。虽然年长儿童和成年人通常表现出轻微或无症状,但他们仍可能是病毒的潜在携带者。因此,采用高效、准确、快速的检测方法,及时发现传染源并迅速阻止传播,是遏制疫情可能蔓延的重要手段。然而,HRSV 感染的临床表现很难与其他呼吸道病毒引起的急性呼吸道感染区分开来,其鉴别主要依赖于病原体检测的结果。本文根据检测原理总结了四种常用的 HRSV 检测方法:抗原检测、核酸检测、抗体检测和病毒分离。总结并比较了这四种方法的优缺点、原理和适用范围。此外,还综述了 HRSV 检测方法的研究进展和前景。
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[Research progress on detection methods for human respiratory syncytial virus].

Human respiratory syncytial virus (HRSV) can infect individuals of all ages, with children under five years old, the elderly, and immunocompromised persons as the main high-risk groups. Although older children and adults often exhibit mild or no symptoms, they may still be potential carriers of the virus. Therefore, employing efficient, accurate, and rapid detection methods to timely identify infection sources and quickly halt transmission is an important means to curb the potential spread of the epidemic. However, the clinical manifestations of HRSV infection are difficult to distinguish from acute respiratory infections caused by other respiratory viruses, and the identification relies on the results of pathogen testing. This article summarizes four commonly used detection methods for HRSV based on detection principles: antigen detection, nucleic acid testing, antibody detection, and virus isolation. The advantages, disadvantages, principles, and applicable scenarios of these four methods are summarized and compared. Furthermore, the research progress and prospects of HRSV detection methods are reviewed.

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来源期刊
中华预防医学杂志
中华预防医学杂志 Medicine-Medicine (all)
CiteScore
1.20
自引率
0.00%
发文量
12678
期刊介绍: Chinese Journal of Preventive Medicine (CJPM), the successor to Chinese Health Journal , was initiated on October 1, 1953. In 1960, it was amalgamated with the Chinese Medical Journal and the Journal of Medical History and Health Care , and thereafter, was renamed as People’s Care . On November 25, 1978, the publication was denominated as Chinese Journal of Preventive Medicine . The contents of CJPM deal with a wide range of disciplines and technologies including epidemiology, environmental health, nutrition and food hygiene, occupational health, hygiene for children and adolescents, radiological health, toxicology, biostatistics, social medicine, pathogenic and epidemiological research in malignant tumor, surveillance and immunization.
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