周边视网膜屈光的特征及其在不同屈光状态儿童中的作用。

IF 1.8 4区 医学 Q3 OPHTHALMOLOGY Journal of Ophthalmology Pub Date : 2024-08-08 eCollection Date: 2024-01-01 DOI:10.1155/2024/7712516
Qi Zhao, Yanhua Wang, Tiangang Liang, Weixiang Nie, Pei Xue, Jie Cheng
{"title":"周边视网膜屈光的特征及其在不同屈光状态儿童中的作用。","authors":"Qi Zhao, Yanhua Wang, Tiangang Liang, Weixiang Nie, Pei Xue, Jie Cheng","doi":"10.1155/2024/7712516","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Peripheral retinal refraction plays a crucial role in myopia, but the specific mechanism is not clear. We refined the retinal partitions to explore the characteristics of peripheral retinal refraction and its role in emmetropic, low, and moderate myopic children aged 6 to 12 years.</p><p><strong>Methods: </strong>A total of 814 subjects (814 eyes) were enrolled in the study. The participants were divided into three groups according to the central spherical equivalent refraction (SER), which were emmetropia group (E), low myopia group (LM) and moderate myopia group (MM). Multispectral refractive topography (MRT) was used to measure the retinal absolute and relative refractive difference value (RDV) in different regions. The range was divided into superior, inferior, temporal, and nasal RDV (SRDV, IRDV, TRDV, and NRDV) on the basis of several concentric circles extending outward from the macular fovea (RDV15, RDV30, RDV45, RDV30-15, RDV45-30, and RDV-45). Kruskal-Wallis test was used to analyze the differences of peripheral refraction for all the regions among the three groups. Spearman rank correlation was performed to explore correlations between SER and RDV, axial length (AL) and RDV.</p><p><strong>Results: </strong>The absolute value of RDV decreased with increasing degree of myopia in all regions (<i>P</i> < 0.01). Subjects with different refractive degrees had different relative value of RDV. In nasal position within 45° and temporal position within 30°, the peripheral retina exhibited significantly different relative hyperopic refractive status among Group <i>E</i>, Group LM, and Group MM (<i>P</i> < 0.05). SER was negatively correlated with NRDV within 30° (especially in the range of NRDV30-15) (<i>r</i> = -0.141, <i>P</i> < 0.01), positively correlated with TRDV within 15° (<i>r</i> = 0.080, <i>P</i> = 0.023), and not significantly correlated with SRDV and IRDV when the retina was divided into four parts. AL was positively correlated with NRDV within 30° (especially in the range of NRDV30-15) (<i>r</i> = 0.109, <i>P</i> = 0.002), negatively correlated with TRDV within 15° (<i>r</i> = -0.095, <i>P</i> = 0.007).</p><p><strong>Conclusions: </strong>The peripheral defocus has significant implications for the genesis of myopia. The peripheral defocus of the horizontal direction, especially within the range of NRDV30, has greater effect on the development of myopia in children. Higher NRDV30 is associated with lower SER and longer AL.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2024 ","pages":"7712516"},"PeriodicalIF":1.8000,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326877/pdf/","citationCount":"0","resultStr":"{\"title\":\"Characteristics of Peripheral Retinal Refraction and Its Role in Children with Different Refractive States.\",\"authors\":\"Qi Zhao, Yanhua Wang, Tiangang Liang, Weixiang Nie, Pei Xue, Jie Cheng\",\"doi\":\"10.1155/2024/7712516\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Peripheral retinal refraction plays a crucial role in myopia, but the specific mechanism is not clear. We refined the retinal partitions to explore the characteristics of peripheral retinal refraction and its role in emmetropic, low, and moderate myopic children aged 6 to 12 years.</p><p><strong>Methods: </strong>A total of 814 subjects (814 eyes) were enrolled in the study. The participants were divided into three groups according to the central spherical equivalent refraction (SER), which were emmetropia group (E), low myopia group (LM) and moderate myopia group (MM). Multispectral refractive topography (MRT) was used to measure the retinal absolute and relative refractive difference value (RDV) in different regions. The range was divided into superior, inferior, temporal, and nasal RDV (SRDV, IRDV, TRDV, and NRDV) on the basis of several concentric circles extending outward from the macular fovea (RDV15, RDV30, RDV45, RDV30-15, RDV45-30, and RDV-45). Kruskal-Wallis test was used to analyze the differences of peripheral refraction for all the regions among the three groups. Spearman rank correlation was performed to explore correlations between SER and RDV, axial length (AL) and RDV.</p><p><strong>Results: </strong>The absolute value of RDV decreased with increasing degree of myopia in all regions (<i>P</i> < 0.01). Subjects with different refractive degrees had different relative value of RDV. In nasal position within 45° and temporal position within 30°, the peripheral retina exhibited significantly different relative hyperopic refractive status among Group <i>E</i>, Group LM, and Group MM (<i>P</i> < 0.05). SER was negatively correlated with NRDV within 30° (especially in the range of NRDV30-15) (<i>r</i> = -0.141, <i>P</i> < 0.01), positively correlated with TRDV within 15° (<i>r</i> = 0.080, <i>P</i> = 0.023), and not significantly correlated with SRDV and IRDV when the retina was divided into four parts. AL was positively correlated with NRDV within 30° (especially in the range of NRDV30-15) (<i>r</i> = 0.109, <i>P</i> = 0.002), negatively correlated with TRDV within 15° (<i>r</i> = -0.095, <i>P</i> = 0.007).</p><p><strong>Conclusions: </strong>The peripheral defocus has significant implications for the genesis of myopia. The peripheral defocus of the horizontal direction, especially within the range of NRDV30, has greater effect on the development of myopia in children. Higher NRDV30 is associated with lower SER and longer AL.</p>\",\"PeriodicalId\":16674,\"journal\":{\"name\":\"Journal of Ophthalmology\",\"volume\":\"2024 \",\"pages\":\"7712516\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326877/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2024/7712516\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2024/7712516","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

导言:周边视网膜屈光在近视中起着至关重要的作用,但具体机制尚不清楚。我们对视网膜分区进行了改进,以探究6至12岁散光、低度和中度近视儿童视网膜周边屈光的特征及其作用:研究共招募了 814 名受试者(814 只眼睛)。根据中心球面等效屈光度(SER)将受试者分为三组,即屈光不正组(E)、低度近视组(LM)和中度近视组(MM)。多光谱屈光地形图(MRT)用于测量不同区域的视网膜绝对和相对屈光差值(RDV)。根据从黄斑窝向外延伸的几个同心圆(RDV15、RDV30、RDV45、RDV30-15、RDV45-30 和 RDV-45),将范围分为上、下、颞和鼻 RDV(SRDV、IRDV、TRDV 和 NRDV)。Kruskal-Wallis 检验用于分析三组之间所有区域周边屈光度的差异。斯皮尔曼秩相关检验探讨了 SER 与 RDV、轴向长度(AL)与 RDV 之间的相关性:所有区域的 RDV 绝对值都随着近视度数的增加而降低(P < 0.01)。不同屈光度的受试者有不同的 RDV 相对值。在45°以内的鼻侧位置和30°以内的颞侧位置,E组、LM组和MM组的周边视网膜表现出显著不同的相对远视屈光状态(P < 0.05)。SER 与 30°以内的 NRDV 呈负相关(尤其是在 NRDV30-15 范围内)(r = -0.141,P < 0.01),与 15°以内的 TRDV 呈正相关(r = 0.080,P = 0.023),而将视网膜分为四部分时,SER 与 SRDV 和 IRDV 的相关性不明显。AL 与 30° 内的 NRDV 呈正相关(尤其是在 NRDV30-15 范围内)(r = 0.109,P = 0.002),与 15° 内的 TRDV 呈负相关(r = -0.095,P = 0.007):结论:周边离焦对近视的形成有重要影响。水平方向的周边离焦,尤其是在 NRDV30 范围内,对儿童近视的发展影响更大。NRDV30 越高,SER 越低,AL 越长。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Characteristics of Peripheral Retinal Refraction and Its Role in Children with Different Refractive States.

Introduction: Peripheral retinal refraction plays a crucial role in myopia, but the specific mechanism is not clear. We refined the retinal partitions to explore the characteristics of peripheral retinal refraction and its role in emmetropic, low, and moderate myopic children aged 6 to 12 years.

Methods: A total of 814 subjects (814 eyes) were enrolled in the study. The participants were divided into three groups according to the central spherical equivalent refraction (SER), which were emmetropia group (E), low myopia group (LM) and moderate myopia group (MM). Multispectral refractive topography (MRT) was used to measure the retinal absolute and relative refractive difference value (RDV) in different regions. The range was divided into superior, inferior, temporal, and nasal RDV (SRDV, IRDV, TRDV, and NRDV) on the basis of several concentric circles extending outward from the macular fovea (RDV15, RDV30, RDV45, RDV30-15, RDV45-30, and RDV-45). Kruskal-Wallis test was used to analyze the differences of peripheral refraction for all the regions among the three groups. Spearman rank correlation was performed to explore correlations between SER and RDV, axial length (AL) and RDV.

Results: The absolute value of RDV decreased with increasing degree of myopia in all regions (P < 0.01). Subjects with different refractive degrees had different relative value of RDV. In nasal position within 45° and temporal position within 30°, the peripheral retina exhibited significantly different relative hyperopic refractive status among Group E, Group LM, and Group MM (P < 0.05). SER was negatively correlated with NRDV within 30° (especially in the range of NRDV30-15) (r = -0.141, P < 0.01), positively correlated with TRDV within 15° (r = 0.080, P = 0.023), and not significantly correlated with SRDV and IRDV when the retina was divided into four parts. AL was positively correlated with NRDV within 30° (especially in the range of NRDV30-15) (r = 0.109, P = 0.002), negatively correlated with TRDV within 15° (r = -0.095, P = 0.007).

Conclusions: The peripheral defocus has significant implications for the genesis of myopia. The peripheral defocus of the horizontal direction, especially within the range of NRDV30, has greater effect on the development of myopia in children. Higher NRDV30 is associated with lower SER and longer AL.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Ophthalmology
Journal of Ophthalmology MEDICINE, RESEARCH & EXPERIMENTAL-OPHTHALMOLOGY
CiteScore
4.30
自引率
5.30%
发文量
194
审稿时长
6-12 weeks
期刊介绍: Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.
期刊最新文献
Retinal Layer and Choroidal Changes in Deep and Scuba Divers: Evidence of Pachychoroid Spectrum-Like Findings. Pilot Study on Postoperative Toric Intraocular Lens Alignment: Comparing Casia2 and Photoshop Imaging Techniques. StreamLight Single-Step Transepithelial Photorefractive Keratectomy (PRK) for Myopia and Myopic Astigmatism. Comparison of Phacoemulsification Alone and With Trabecular Microbypass Stent in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma: An 18-Month Outcome Study. Exploring the Role of ROCK Inhibition in Corneal Edema Through Crosstalk Between Epithelial and Endothelial Cells.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1