作为脑血管风险标志物的颈动脉周围脂肪

Riccardo Cau, Nicoletta Anzalone, Lorenzo Mannelli, Myriam Edjlali, Antonella Balestrieri, Valentina Nardi, Giuseppe Lanzino, Amir Lerman, Jasjit S Suri, Luca Saba
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引用次数: 0

摘要

血管炎症被广泛认为是动脉粥样硬化过程中的一个重要因素,尤其是在斑块的形成和发展方面。传统的检测方法,如测量循环炎症生物标志物,缺乏精确性,无法确定血管炎症的具体部位。在这种情况下,无创成像模式可以检测血管周围脂肪的变化,作为血管炎症的标志物。本综述旨在全面概述与颈动脉周围脂肪及其病理生理学相关的关键概念。此外,我们还研究了有关颈动脉周围脂肪与斑块易损性特征和脑血管事件相关性的现有文献。最后,我们仔细研究了颈动脉周围脂肪无创评估的优势和局限性。
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Pericarotid Fat as a Marker of Cerebrovascular Risk.

Vascular inflammation is widely recognized as an important factor in the atherosclerotic process, particularly in terms of plaque development and progression. Conventional tests, such as measuring circulating inflammatory biomarkers, lack the precision to identify specific areas of vascular inflammation. In this context, noninvasive imaging modalities can detect perivascular fat changes, serving as a marker of vascular inflammation. This review aims to provide a comprehensive overview of the key concepts related to perivascular carotid fat and its pathophysiology. Additionally, we examine the existing literature on the association of pericarotid fat with features of plaque vulnerability and cerebrovascular events. Finally, we scrutinize the advantages and limitations of the noninvasive assessment of pericarotid fat.

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