机器人心脏跳动全内窥镜冠状动脉搭桥术中的双侧胸内动脉移植术:10年疗效。

IF 3.3 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Annals of cardiothoracic surgery Pub Date : 2024-07-31 Epub Date: 2024-07-18 DOI:10.21037/acs-2024-rcabg-0016
Sarah Nisivaco, Riya Bhasin, Hiroto Kitahara, Brooke Patel, Charocka Coleman, Kaitlyn Grady, Won Hee Oh, Husam H Balkhy
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引用次数: 0

摘要

背景:使用双侧胸内动脉(BITA)的多动脉移植术(MAG)优于单侧胸内动脉(ITA)和静脉移植术,但是胸骨伤口感染(SWI)是使用双侧胸内动脉移植术的一个障碍,尤其是糖尿病和肥胖患者。包括机器人全内镜冠状动脉搭桥术(TECAB)在内的保留胸骨的方法可以降低这种风险。我们回顾了机器人TECAB与BITA移植术的效果:从2013年7月7日至2024年4月4日,共有871名患者在我院接受了机器人TECAB手术。方法:2013 年 7 月至 2024 年 4 月期间,我院共有 871 名患者接受了机器人 TECAB,其中 406 名患者接受了 BITA 移植,是本次回顾的对象。我们回顾了TECAB术后接受经皮冠状动脉介入(PCI)混合血管重建术的患者的早期和中期临床结果以及血管造影的通畅情况。所有病例均通过心脏跳动机器人方法进行,并放置了标准的TECAB端口:结果:患者平均年龄(67±9)岁,16%为女性。胸外科医师协会(STS)平均风险为 1.47%±2.2%。39%的人患有糖尿病(15%为胰岛素依赖型),39%的人体重指数(BMI)≥30 kg/m2。20%的患者射血分数(EF)≤40%。98%的病例在非泵下完成,没有转为胸骨切开术的病例。每位患者的平均移植物数量为(2.2±0.4)个。平均重症监护室(ICU)和住院时间(LOS)分别为(1.22±0.62)天和(2.44±0.83)天。术后并发症包括13%的心房颤动、3.4%的急性肾损伤(AKI)、0.7%因出血返回手术室、0.2%的术后心肌梗死(MI)和0.2%的中风。30天死亡率为1.2%[观察/预期(O/E):0.89]。恢复全面活动和工作的平均时间分别为 14±8.6 天和 17±13 天。222 名患者(50%)进行了 "高级 "混合血管重建(至少有两个动脉移植物和支架)。在这批患者中,ITA早期移植物的通畅率为271/278(98%),其中左ITA至左前降支动脉(LITA-LAD)的通畅率为100%。所有患者的中期随访平均为 51±36 个月(最长随访时间为 10 年)。全因死亡率为 13%,心脏死亡率为 2.5%。96%的患者无心绞痛,94%的患者无重复血管重建:结论:使用心脏跳动机器人 TECAB 方法有助于通过 BITA 移植实现左冠状动脉系统的多血管动脉血管再通,10 年疗效极佳。
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Bilateral internal thoracic artery grafting in robotic beating-heart totally endoscopic coronary artery bypass: 10-year outcomes.

Background: Multi-arterial grafting (MAG) with bilateral internal thoracic arteries (BITAs) is superior to single internal thoracic artery (ITA) and veins, however, sternal wound infection (SWI) is a deterrent to using BITA, especially in diabetic and obese patients. Sternal-sparing approaches, including robotic totally endoscopic coronary artery bypass (TECAB), may mitigate this risk. We reviewed outcomes of robotic TECAB with BITA grafting.

Methods: A total of 871 patients underwent robotic TECAB at our institution from 7/2013 to 4/2024. Of these, 406 patients received BITA grafts and are the subject of this review. Early and mid-term clinical outcomes were reviewed and angiographic patency in those undergoing hybrid revascularization with percutaneous coronary intervention (PCI) after TECAB. All cases were performed via a beating-heart robotic approach, with standard TECAB port placement.

Results: The mean age of the cohort was 67±9 years and 16% were female. The mean Society of Thoracic Surgeons (STS) risk was 1.47%±2.2%. Thirty-nine percent were diabetic (15% insulin-dependent) and 39% had a body mass index (BMI) ≥30 kg/m2. Twenty percent had an ejection fraction (EF) ≤40%. Ninety-eight percent of cases were completed off-pump and there were no conversions to sternotomy. The mean number of grafts per patient was 2.2±0.4. The mean intensive care unit (ICU) and hospital length of stay (LOS) were 1.22±0.62 and 2.44±0.83 days, respectively. Postoperative complications included atrial fibrillation in 13%, acute kidney injury (AKI) in 3.4%, return to theatre for bleeding in 0.7%, postoperative myocardial infarction (MI) in 0.2%, and stroke in 0.2%. Thirty-day mortality was 1.2% [observed/expected (O/E): 0.89]. Return to full activities and work occurred at mean of 14±8.6 and 17±13 days, respectively. Two hundred and two patients (50%) had 'advanced' hybrid revascularization (with at least two arterial grafts and stents). ITA early graft patency in this cohort of patients was 271/278 (98%) with 100% left ITA to left anterior descending artery (LITA-LAD) patency. Mid-term follow-up was complete in all patients at mean of 51±36 months (longest follow-up at 10 years). All-cause mortality was 13% and cardiac-mortality was 2.5%. Freedom from angina was 96%, and freedom from repeat revascularization was 94%.

Conclusions: Use of the beating-heart robotic TECAB approach facilitates BITA grafting to achieve multi-vessel arterial revascularization of the left coronary system, with excellent 10-year outcomes.

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