利用免疫染色法诊断卵巢转移手术后伴有子宫转移的小肠癌罕见病例

IF 0.6 Q4 ONCOLOGY Case Reports in Oncological Medicine Pub Date : 2024-08-10 eCollection Date: 2024-01-01 DOI:10.1155/2024/8551816
Sachiko Nagao, Motoki Matsuura, Shoko Kurokawa, Masato Tamate, Taishi Akimoto, Tsuyoshi Saito
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引用次数: 0

摘要

从生殖器外部位转移到子宫的情况非常罕见。我们介绍了一例女性病例,她曾接受过小肠癌手术,随后出现左侧卵巢和子宫转移。一名 50 多岁的无子宫妇女因患小肠癌接受了腹腔镜小肠部分切除术和淋巴结清扫术。五个月后,计算机断层扫描(CT)发现左侧卵巢肿瘤和腹水。她接受了双侧附件切除术和辅助化疗,卵巢肿瘤被诊断为小肠癌转移。小肠癌手术两年后,正电子发射断层扫描(PET)-CT 扫描发现子宫积液。宫颈细胞学检查未发现上皮内病变或恶性肿瘤。子宫内膜组织学检查显示为子宫腺癌。患者接受了全腹子宫切除术,随后接受了辅助化疗。子宫肿瘤的组织病理学和免疫组化结果显示,这是一种小肠癌转移瘤(细胞角蛋白7 [CK7] [-]、细胞角蛋白20 [CK20] [+]、特殊AT-富序列结合蛋白2 [SATB2] [+]、配对盒基因2 [PAX2] [-]和雌激素受体[ER] [-])。对于癌症患者来说,组织病理学和免疫组化对于区分原发性和转移性肿瘤以及指导治疗方案的选择非常重要。
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A Rare Case of Small Intestinal Cancer With Uterine Metastasis After Surgery for Ovarian Metastasis, Diagnosed Using Immunostaining.

Uterine metastases from extragenital sites are rare. We present a case of a woman who had undergone surgery for small intestinal cancer and subsequently developed metastases in her left ovary and uterus. A nulliparous woman in her 50s underwent laparoscopic partial small bowel resection with lymph node dissection for small intestinal cancer. Five months later, computed tomography (CT) revealed a left ovarian tumor and ascites. She underwent bilateral adnexectomy and adjuvant chemotherapy, and the ovarian tumor was diagnosed as a small intestinal cancer metastasis. Two years after the small intestinal cancer surgery, a positron emission tomography (PET)-CT scan revealed a uterine accumulation. Cervical cytology was negative for intraepithelial lesion or malignancy. Endometrial histology showed an adenocarcinoma of the uterus. The patient underwent total abdominal hysterectomy followed by adjuvant chemotherapy. Histopathology and immunohistochemistry of the uterine tumor revealed that it was a metastasis of small intestinal cancer (Cytokeratin 7 [CK7] [-], Cytokeratin 20 [CK20] [+], Special AT-Rich Sequence-Binding Protein 2 [SATB2] [+], Paired Box Gene 2 [PAX2] [-], and estrogen receptor [ER] [-]). In patients with cancer, histopathology and immunohistochemistry are important for distinguishing between primary and metastatic tumors and for guiding the choice of treatment.

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来源期刊
自引率
0.00%
发文量
11
审稿时长
16 weeks
期刊介绍: Case Reports in Oncological Medicine is a peer-reviewed, Open Access journal that publishes case reports and case series related to breast cancer, lung cancer, gastrointestinal cancer, skin cancer, head and neck cancer, paediatric oncology, neurooncology as well as genitourinary cancer.
期刊最新文献
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