综述了碳点的绿色合成以及在药物输送、生物传感器和生物成像领域的生物应用。

IF 3.2 4区 化学 Q2 CHEMISTRY, ANALYTICAL Luminescence Pub Date : 2024-08-18 DOI:10.1002/bio.4870
Arshdeep Chopra, Yogindra Kumari, Ajay Pal Singh, Yash Sharma
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引用次数: 0

摘要

自纳米科学和纳米技术诞生以来,碳点(CD)一直是纳米领域的基础概念,并主导着纳米领域的发展。由于碳点具有众多独特的结构、物理化学和光化学特性,因此是一个可用于生物、技术、催化和其他领域的引人入胜的平台。目前已经有多种碳点问世,并根据其合成过程和发光特性对其进行了评估。与其他碳纳米结构相比,碳点具有生物相容性、毒性较低以及最重要的荧光特性等优点。本综述将重点介绍从天然资源中提取的 CD 在表征、应用和合成技术方面的最新进展。它还将指导科学家们创造一种更实用、更有效、更环保的可调碳点合成技术。碳点具有低毒性和低成本的特点,在生物材料传感、酶、化学污染和温度传感等各种事物的检测和传感方面满足了新时代对更高选择性和灵敏度的要求。它的各种特性,如光学特性、化学发光和形态分析等,使其成为生物成像、药物输送、生物传感器和癌症诊断的良好选择。
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A review on green synthesis, biological applications of carbon dots in the field of drug delivery, biosensors, and bioimaging

Since the beginning of nanoscience and nanotechnology, carbon dots (CDs) have been the foundational idea and have dominated the growth of the nano-field. CDs are an intriguing platform for utilization in biology, technology, catalysis, and other fields thanks to their numerous distinctive structural, physicochemical, and photochemical characteristics. Since several carbon dots have already been created, they have been assessed based on their synthesis process, and luminescence characteristics. Due to their biocompatibility, less toxic effects, and most significantly their fluorescent features in contrast to other carbon nanostructures, CDs have several benefits. This review focuses on the most recent advancements in the characterization, applications, and synthesis techniques used for CDs made from natural sources. It will also direct scientists in the creation of a synthesis technique for adjustable carbon dots that is more practical, effective, and environmentally benign. With low toxicity and low cost, CDs are meeting the new era's requirements for more selectivity and sensitivity in the detection and sensing of various things, such as biomaterial sensing, enzymes, chemical contamination, and temperature sensing. Its variety of properties, such as optical properties, chemiluminescence, and morphological analysis, make it a good option to use in bioimaging, drug delivery, biosensors, and cancer diagnosis.

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来源期刊
Luminescence
Luminescence 生物-生化与分子生物学
CiteScore
5.10
自引率
13.80%
发文量
248
审稿时长
3.5 months
期刊介绍: Luminescence provides a forum for the publication of original scientific papers, short communications, technical notes and reviews on fundamental and applied aspects of all forms of luminescence, including bioluminescence, chemiluminescence, electrochemiluminescence, sonoluminescence, triboluminescence, fluorescence, time-resolved fluorescence and phosphorescence. Luminescence publishes papers on assays and analytical methods, instrumentation, mechanistic and synthetic studies, basic biology and chemistry. Luminescence also publishes details of forthcoming meetings, information on new products, and book reviews. A special feature of the Journal is surveys of the recent literature on selected topics in luminescence.
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