澳大利亚音乐节上的新型减毒措施:澳大利亚维多利亚州新兴毒品网络毒性监测方法的试点实施。

IF 3 3区 医学 Q2 SUBSTANCE ABUSE Drug and alcohol review Pub Date : 2024-08-19 DOI:10.1111/dar.13922
Rebekka Syrjanen, Martin Dutch, Shaun L. Greene, Tom Lyons, Ginny McKinnon, Dimitri Gerostamoulos, Jennifer L. Schumann, the EDNAV Project Research Group
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引用次数: 0

摘要

导言:音乐节的减害策略旨在为观众创造一个更安全的环境。澳大利亚维多利亚州新兴毒品网络(EDNAV)项目是一个全州范围的毒物监测网络,它从因非法药物相关中毒而入院的患者样本中获取毒品情报。本刊物介绍了在现场医疗设施内对身体状况严重不适的节日观众进行毒物监测的初步结果:方法:从三个音乐节(2022/2023 年)中出现严重非法药物相关中毒症状的观众身上采集血液样本。通过液相色谱-串联质谱法对血液样本中的 700 多种药物和违禁药物进行分析:结果:在这三个节日中,共有 1603 人次就诊,其中 228 人次与违禁药物有关。为 24 名患者采集了血液样本,中位年龄为 22 岁(18-39 岁不等)。每位患者报告的毒品数量中位数为 2 种(范围为 1-5 种),经分析确认的毒品数量中位数为 4 种(范围为 0-8 种)。报告暴露最多的毒品与分析结果一致:3,4-亚甲二氧基甲基苯丙胺(报告人数=17,检测人数=20)、氯胺酮(报告人数=9,检测人数=13)和可卡因(报告人数=9,检测人数=12)。在18名患者中检测出了一种未报告的非法药物和/或新型精神活性物质(NPS),包括甲基苯丙胺(10人)、卡西酮(7人)、苯二氮卓类NPS(6人)、N-乙基苯丙胺(1人)、3-羟基苯环利定(1人)和/或4-羟基-N-甲基-N-异丙基色胺(1人):EDNAV 毒物监测是节日减低危害的多方面方法中的另一种工具。持续的数据收集将有助于确定高风险药物使用模式的特征,从而为音乐节观众和主要利益相关者提供以证据为基础的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Novel harm reduction measures at music festivals in Australia: Pilot implementation of the Emerging Drugs Network of Australia–Victoria toxicosurveillance methodology

Introduction

Harm reduction strategies at music festivals seek to create a safer environment for patrons. The Emerging Drugs Network of Australia–Victoria (EDNAV) project is a state-wide toxicosurveillance network that derives drug intelligence from a sample of patients presenting to hospital with illicit drug-related toxicity. This publication describes the preliminary outcomes of conducting toxicosurveillance for critically unwell festival patrons within on-site medical facilities.

Methods

Blood samples were collected from patrons who presented with severe illicit drug-related toxicity across three festivals (2022/2023). Blood samples were analysed via liquid chromatography–tandem mass spectrometry for over 700 pharmaceutical and illicit drugs.

Results

There were 1603 individual medical encounters across the festivals, 228 of which were illicit drug related. A blood sample was collected for 24 patients, with a median age of 22 years (range 18–39 years). A median of two drugs (range 1–5 drugs) were reported and four drugs (range 0–8 drugs) were analytically confirmed per patient. The most frequently reported exposures were congruent with analytical results, 3,4-methylenedioxymethamphetamine (reported n = 17, detected n = 20), ketamine (reported n = 9, detected n = 13) and cocaine (reported n = 9, detected n = 12). An unreported illicit drug and/or new psychoactive substance (NPS) was detected in 18 patients, including methylamphetamine (n = 10), a cathinone (n = 7), benzodiazepine-type NPS (n = 6), N-ethylamphetamine (n = 1), 3-hydroxyphencyclidine (n = 1) and/or 4-hydroxy-N-methyl-N-isopropyltryptamine (n = 1).

Discussion and Conclusions

EDNAV toxicosurveillance serves as an additional tool within a multi-faceted approach to harm reduction at festivals. Continued data collection will allow for the characterisation of high-risk drug use patterns to provide evidence-based messaging to festival patrons and key stakeholders.

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来源期刊
Drug and alcohol review
Drug and alcohol review SUBSTANCE ABUSE-
CiteScore
4.80
自引率
10.50%
发文量
151
期刊介绍: Drug and Alcohol Review is an international meeting ground for the views, expertise and experience of all those involved in studying alcohol, tobacco and drug problems. Contributors to the Journal examine and report on alcohol and drug use from a wide range of clinical, biomedical, epidemiological, psychological and sociological perspectives. Drug and Alcohol Review particularly encourages the submission of papers which have a harm reduction perspective. However, all philosophies will find a place in the Journal: the principal criterion for publication of papers is their quality.
期刊最新文献
Correction to 'Alcohol-related injury hospitalisations in relation to alcohol policy changes, Northern Territory, Australia, 2007-2022: A joinpoint regression analysis'. Does parental cohort increase the likelihood of underage alcohol consumption in Australia? Protecting children from tobacco products in retail environments: A review of Australian tobacco control laws. Issue Information Thank you to our independent reviewers for 2024
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