{"title":"SARS-CoV-2 严重急性呼吸窘迫综合征中的减压气道通气和俯卧位:病例报告","authors":"Rita Pino-Pino , Emilia Guajardo-Moyano , Felipe Castillo-Merino , Sebastián Ugarte-Ubiergo","doi":"10.1016/j.rmclc.2024.07.006","DOIUrl":null,"url":null,"abstract":"<div><p>COVID-19 had a wide spectrum of clinical manifestations, from asymptomatic to severe forms. A significant percentage of infected subjects develop acute respiratory distress syndrome (ARDS).</p></div><div><h3>Objective</h3><p>Use of prone position and airway pressure release ventilation (APRV) to improve oxygenation in a patient with COVID-19 ARDS.</p></div><div><h3>Clinical case</h3><p>73-year-old patient, with diabetes and high blood pressure, presented with a diagnosis of severe COVID-19 pneumonia, which required the use of invasive mechanical ventilation (IMV). In the context of poor oxygenation, difficult sedation and blood gas deterioration, APRV is started. With the progression of pulmonary involvement, ventilatory strategies were not very fruitful, so it was decided to use prone<!--> <!-->+<!--> <!-->APRV.</p></div><div><h3>Results</h3><p>a total of 574<!--> <!-->hours in IMV and 274<!--> <!-->hours in prone divided into 3 cycles of duration. The first cycles of prone<!--> <!-->+<!--> <!-->APRV were relevant in terms of improvements in PaO<sub>2</sub>/FiO<sub>2</sub> (PaFi), however, from the third prone event, there were no significant changes.</p></div><div><h3>Conclusions</h3><p>prone<!--> <!-->+<!--> <!-->APRV was adequate to the patient's requirements, however, the clinical course of the disease produced irreversible deterioration.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 330-335"},"PeriodicalIF":0.2000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0716864024000555/pdfft?md5=319171c443d73212dbe15056104d5ed0&pid=1-s2.0-S0716864024000555-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Ventilación con liberación de presión en la vía aérea y posición prono en el síndrome de distrés respiratorio agudo grave por SARS-CoV-2: reporte de caso\",\"authors\":\"Rita Pino-Pino , Emilia Guajardo-Moyano , Felipe Castillo-Merino , Sebastián Ugarte-Ubiergo\",\"doi\":\"10.1016/j.rmclc.2024.07.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>COVID-19 had a wide spectrum of clinical manifestations, from asymptomatic to severe forms. A significant percentage of infected subjects develop acute respiratory distress syndrome (ARDS).</p></div><div><h3>Objective</h3><p>Use of prone position and airway pressure release ventilation (APRV) to improve oxygenation in a patient with COVID-19 ARDS.</p></div><div><h3>Clinical case</h3><p>73-year-old patient, with diabetes and high blood pressure, presented with a diagnosis of severe COVID-19 pneumonia, which required the use of invasive mechanical ventilation (IMV). In the context of poor oxygenation, difficult sedation and blood gas deterioration, APRV is started. With the progression of pulmonary involvement, ventilatory strategies were not very fruitful, so it was decided to use prone<!--> <!-->+<!--> <!-->APRV.</p></div><div><h3>Results</h3><p>a total of 574<!--> <!-->hours in IMV and 274<!--> <!-->hours in prone divided into 3 cycles of duration. The first cycles of prone<!--> <!-->+<!--> <!-->APRV were relevant in terms of improvements in PaO<sub>2</sub>/FiO<sub>2</sub> (PaFi), however, from the third prone event, there were no significant changes.</p></div><div><h3>Conclusions</h3><p>prone<!--> <!-->+<!--> <!-->APRV was adequate to the patient's requirements, however, the clinical course of the disease produced irreversible deterioration.</p></div>\",\"PeriodicalId\":31544,\"journal\":{\"name\":\"Revista Medica Clinica Las Condes\",\"volume\":\"35 3\",\"pages\":\"Pages 330-335\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S0716864024000555/pdfft?md5=319171c443d73212dbe15056104d5ed0&pid=1-s2.0-S0716864024000555-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica Clinica Las Condes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0716864024000555\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0716864024000555","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Ventilación con liberación de presión en la vía aérea y posición prono en el síndrome de distrés respiratorio agudo grave por SARS-CoV-2: reporte de caso
COVID-19 had a wide spectrum of clinical manifestations, from asymptomatic to severe forms. A significant percentage of infected subjects develop acute respiratory distress syndrome (ARDS).
Objective
Use of prone position and airway pressure release ventilation (APRV) to improve oxygenation in a patient with COVID-19 ARDS.
Clinical case
73-year-old patient, with diabetes and high blood pressure, presented with a diagnosis of severe COVID-19 pneumonia, which required the use of invasive mechanical ventilation (IMV). In the context of poor oxygenation, difficult sedation and blood gas deterioration, APRV is started. With the progression of pulmonary involvement, ventilatory strategies were not very fruitful, so it was decided to use prone + APRV.
Results
a total of 574 hours in IMV and 274 hours in prone divided into 3 cycles of duration. The first cycles of prone + APRV were relevant in terms of improvements in PaO2/FiO2 (PaFi), however, from the third prone event, there were no significant changes.
Conclusions
prone + APRV was adequate to the patient's requirements, however, the clinical course of the disease produced irreversible deterioration.