在体外动脉瘤模型中,输送技术对 Woven EndoBridge 部署和分离的影响。

IF 1.7 4区 医学 Q3 Medicine Interventional Neuroradiology Pub Date : 2024-08-22 DOI:10.1177/15910199241273984
Muhammed Amir Essibayi, David J Altschul
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引用次数: 0

摘要

背景:Woven EndoBridge(WEB)装置越来越多地被用于治疗宽颈分叉动脉瘤。在使用较新的 17 系统时,WEB 部署与一种称为不完全或 "粘连 "脱离输送导线的现象有关,这种现象可能导致放置不精确。目前尚未明确避免这一问题的最佳 WEB 操作和输送技术。本研究旨在评估标准的 WEB 置入技术,并确定置入技术和 WEB 粘性对手术成功率的影响:一项使用相同硅胶大脑中动脉瘤模型(n = 32)的体外研究评估了通过 VIA 17 微导管以三种技术部署 WEB(6 × 2 毫米)的情况:推线的 "加载"、"中立 "和 "张力"。微导管的位置与 WEB 设备的位置不同。在尝试分离过程中,对编织 EndoBridge 的粘性进行分级。主要结果是剥离粘性和尝试次数,使用费雪精确检验对不同技术进行比较:结果:与正向加载或中性技术相比,张力技术导致的粘连脱落和脱落尝试次数明显较少(P 结论:张力技术可减少不完全粘连:张力技术减少了 WEB 的不完全剥离,实现了精确的单次尝试剥离,优化了递送精度。需要进行活体确认。
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The impact of delivery technique on Woven EndoBridge deployment and detachment in an in vitro aneurysm model.

Background: The Woven EndoBridge (WEB) device is increasingly used for treatment of wide-neck bifurcation aneurysms. With the newer 17 system, WEB deployment has been associated with a phenomenon known as incomplete or "sticky" detachment from the delivery wire, which may lead to imprecise placement. Optimal techniques for WEB manipulation and delivery to avoid this problem are poorly defined. This study aimed to evaluate standard WEB deployment techniques and determine the impact of delivery techniques and WEB stickiness on procedural success.

Methods: An in vitro study using identical silicone middle cerebral artery aneurysm models (n = 32) assessed WEB (6 × 2 mm) deployment through a VIA 17 microcatheter via three techniques that involved: "loading," "neutral," and "tension" on the pusher wire. Microcatheter position was placed in varied positions from the WEB device. Woven EndoBridge stickiness was graded during detachment attempts. Primary outcomes were detachment stickiness and attempt number, compared between techniques using Fisher's exact test.

Results: The tension technique resulted in significantly fewer sticky detachments and detachment attempts compared to forward load or neutral techniques (p < 0.001). Sticky detachment was lower with tension (0% sticky) versus forward load (42% sticky, 8% very sticky) (p < 0.001). Forward load had a 50% rate of stickiness versus 0% with tension and neutral (p < 0.001). Forward load required multiple attempts in 100%, compared to 57% with neutral and 8% with tension (p < 0.001). Higher stickiness grades increased the need for multiple attempts (p < 0.001).

Conclusion: The tension technique reduces incomplete WEB detachment and enables precise single-attempt detachment, optimizing delivery precision. In vivo confirmation is needed.

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来源期刊
CiteScore
2.80
自引率
11.80%
发文量
192
审稿时长
6-12 weeks
期刊介绍: Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...
期刊最新文献
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